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Tenascin

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Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.

Below are the list of possible Tenascin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Tenascin

 Tenascin ELISA Kit
 Tenascin Recombinant
 Tenascin Antibody
Also known as Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (P230) (Tenascin-C) (TN-C).
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortic
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al neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
 TNC ELISA Kit
 TNC Recombinant
 TNC Antibody
 HXB ELISA Kit
 HXB Recombinant
 HXB Antibody
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Tenascin-N

 Tenascin-N ELISA Kit
 Tenascin-N Recombinant
 Tenascin-N Antibody
Also known as Tenascin-N (TN-N).
TNN: Involved in neurite outgrowth and cell migration in hippocampal explants. Belongs to the tenascin family.

Protein type: Extracellular matrix; Secreted; Secreted, signal peptide

Cellular Component: cell surface; proteinaceous extracellular matrix

Molecular Function: identical protein binding; integrin binding

Biological Process: a
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xonogenesis; cell growth; cell migration; cell-matrix adhesion
 Tnn ELISA Kit
 Tnn Recombinant
 Tnn Antibody
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Tenascin-R

 Tenascin-R ELISA Kit
 Tenascin-R Recombinant
 Tenascin-R Antibody
Also known as Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin).
TNR: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangl
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iosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance. Belongs to the tenascin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: cell surface; cytoplasm; lipid raft; nucleoplasm; nucleus; proteinaceous extracellular matrix

Molecular Function: integrin binding

Biological Process: associative learning; extracellular matrix organization and biogenesis; negative regulation of axon extension; negative regulation of axon extension involved in regeneration; negative regulation of cell adhesion; negative regulation of cell-cell adhesion; negative regulation of synaptic transmission; nervous system development; neuromuscular process controlling balance; neuron adhesion; positive regulation of synaptic transmission, glutamatergic; positive regulation of transmission of nerve impulse; regulation of synaptic transmission; synapse organization and biogenesis; telencephalon cell migration
 Tnr ELISA Kit
 Tnr Recombinant
 Tnr Antibody
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Tenascin-X

 Tenascin-X ELISA Kit
 Tenascin-X Recombinant
 Tenascin-X Antibody
Also known as Tenascin-X (TN-X) (Hexabrachion-like protein).
TNXB: Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. Defects in TNXB are the cause of tenascin-X deficiency (TNXD). TNXD leads to an Ehlers-Danlos-like syndrome characterized by hyperextensible skin, hypermobile joints, and tissue fragility. Tenascin-X-deficient patients, however, lack atrophic scars, a major diagnostic criteria for cl
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assic Ehlers- Danlos. Delayed wound healing, which is also common in classic EDS, is only present in a subset of patients. Belongs to the tenascin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: extracellular matrix; extracellular space; fibrillar collagen; intracellular

Molecular Function: heparin binding; integrin binding; protein binding

Biological Process: actin cytoskeleton organization and biogenesis; cell adhesion; collagen metabolic process; elastic fiber assembly

Disease: Ehlers-danlos-like Syndrome Due To Tenascin-x Deficiency; Vesicoureteral Reflux 8
 TNXB ELISA Kit
 TNXB Recombinant
 TNXB Antibody
 HXBL ELISA Kit
 HXBL Recombinant
 HXBL Antibody
 TNX ELISA Kit
 TNX Recombinant
 TNX Antibody
 TNXB1 ELISA Kit
 TNXB1 Recombinant
 TNXB1 Antibody
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Proteins Root Name Listing
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