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TFIIH basal transcription factor complex helicase

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Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex to the core-TFIIH complex.

Below are the list of possible TFIIH basal transcription factor complex helicase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

TFIIH basal transcription factor complex helicase repB subunit

 TFIIH basal transcription factor complex helicase repB subunit ELISA Kit
 TFIIH basal transcription factor complex helicase repB subunit Recombinant
 TFIIH basal transcription factor complex helicase repB subunit Antibody
Also known as TFIIH basal transcription factor complex helicase repB subunit (DNA excision repair cross-complementing protein-3 homolog) (DNA repair helicase repB) (DNA repair protein B).
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex to the core-TFIIH complex.
 repB ELISA Kit
 repB Recombinant
 repB Antibody
 ercc3 ELISA Kit
 ercc3 Recombinant
 ercc3 Antibody
 DDB_G0278729 ELISA Kit
 DDB_G0278729 Recombinant
 DDB_G0278729 Antibody
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TFIIH basal transcription factor complex helicase repD subunit

 TFIIH basal transcription factor complex helicase repD subunit ELISA Kit
 TFIIH basal transcription factor complex helicase repD subunit Recombinant
 TFIIH basal transcription factor complex helicase repD subunit Antibody
Also known as TFIIH basal transcription factor complex helicase repD subunit (DNA excision repair cross-complementing protein-2 homolog) (DNA repair protein D).
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex to the core-TFIIH complex ().
 repD ELISA Kit
 repD Recombinant
 repD Antibody
 ercc2 ELISA Kit
 ercc2 Recombinant
 ercc2 Antibody
 DDB_G0267414 ELISA Kit
 DDB_G0267414 Recombinant
 DDB_G0267414 Antibody
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TFIIH basal transcription factor complex helicase XPB subunit

 TFIIH basal transcription factor complex helicase XPB subunit ELISA Kit
 TFIIH basal transcription factor complex helicase XPB subunit Recombinant
 TFIIH basal transcription factor complex helicase XPB subunit Antibody
Also known as TFIIH basal transcription factor complex helicase XPB subunit (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH 89 kDa subunit) (Xeroderma pigme.
XPB: ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. One of the 6 subunits forming the c
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ore-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. Interacts with PUF60. Interacts with ATF7IP. Interacts with Epstein-Barr virus EBNA2. Belongs to the helicase family. RAD25/XPB subfamily.

Protein type: DNA repair, damage; EC 3.6.4.12; Helicase; Transcription factor

Cellular Component: holo TFIIH complex; nucleoplasm; nucleus

Molecular Function: 3'-5' DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATPase activity; dATP binding; DNA-dependent ATPase activity; GTP binding; peptide binding; protein C-terminus binding; protein kinase activity; protein N-terminus binding; RNA polymerase subunit kinase activity

Biological Process: apoptosis; DNA repair; DNA topological change; hair cell differentiation; nucleotide-excision repair; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; positive regulation of apoptosis; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; protein localization; response to oxidative stress; response to UV; transcription from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; UV protection
 Ercc3 ELISA Kit
 Ercc3 Recombinant
 Ercc3 Antibody
 Xpb ELISA Kit
 Xpb Recombinant
 Xpb Antibody
 Xpbc ELISA Kit
 Xpbc Recombinant
 Xpbc Antibody
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TFIIH basal transcription factor complex helicase XPD subunit

 TFIIH basal transcription factor complex helicase XPD subunit ELISA Kit
 TFIIH basal transcription factor complex helicase XPD subunit Recombinant
 TFIIH basal transcription factor complex helicase XPD subunit Antibody
Also known as TFIIH basal transcription factor complex helicase XPD subunit (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription facto.
ERCC2: ATP-dependent 5'-3' DNA helicase, component of the core- TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH c
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omplex. Involved in the regulation of vitamin-D receptor activity. Might also have a role in aging process and could play a causative role in the generation of skin cancers. Belongs to the helicase family. RAD3/XPD subfamily. One of the six subunits forming the core-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. The interaction with GTF2H2 results in the stimulation of the 5'-->3' helicase activity. Interacts with Epstein-Barr virus EBNA2.

Protein type: EC 3.6.4.12; Helicase

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: cyclin-dependent protein kinase activating kinase holoenzyme complex; cytoplasm; holo TFIIH complex; nucleoplasm; nucleus; spindle; transcription factor TFIID complex

Molecular Function: 5'-3' DNA helicase activity; DNA-dependent ATPase activity; protein binding; protein C-terminus binding; protein kinase activity; protein N-terminus binding; RNA polymerase subunit kinase activity

Biological Process: apoptosis; chromosome segregation; hair cell differentiation; mRNA capping; nucleotide-excision repair; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, preincision complex stabilization; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; response to oxidative stress; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair; UV protection

Disease: Cerebrooculofacioskeletal Syndrome 2; Trichothiodystrophy, Photosensitive; Xeroderma Pigmentosum, Complementation Group D
 ERCC2 ELISA Kit
 ERCC2 Recombinant
 ERCC2 Antibody
 XPD ELISA Kit
 XPD Recombinant
 XPD Antibody
 XPDC ELISA Kit
 XPDC Recombinant
 XPDC Antibody
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