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THO complex

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Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export. Contributes to the integrity of the endogenous trans-acting small interfering RNA (ta-siRNA) pathway. May process or transport a long RNA molecule so that it can be a template for secondary siRNA production. May participate in the trafficking of siRNA precursors to the ARGONAUTE catalytic center. Required for the generation of functional messenger ribonucleoproteins (mRNPs). Plays an important roles in plant innate immunity.

Below are the list of possible THO complex products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

THO complex subunit 1

 THO complex subunit 1 ELISA Kit
 THO complex subunit 1 Recombinant
 THO complex subunit 1 Antibody
Also known as THO complex subunit 1 (AtTHO1) (HPR1 homolog) (AtHPR1).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO1 ELISA Kit
 THO1 Recombinant
 THO1 Antibody
 EMU ELISA Kit
 EMU Recombinant
 EMU Antibody
 HPR1 ELISA Kit
 HPR1 Recombinant
 HPR1 Antibody
 At5g09860 ELISA Kit
 At5g09860 Recombinant
 At5g09860 Antibody
Table BarTOPTable Bar
 

THO complex subunit 2

 THO complex subunit 2 ELISA Kit
 THO complex subunit 2 Recombinant
 THO complex subunit 2 Antibody
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase.
 tho2 ELISA Kit
 tho2 Recombinant
 tho2 Antibody
 SPAC1D4.14 ELISA Kit
 SPAC1D4.14 Recombinant
 SPAC1D4.14 Antibody
 SPAC22F3.14c ELISA Kit
 SPAC22F3.14c Recombinant
 SPAC22F3.14c Antibody
Table BarTOPTable Bar
 

THO complex subunit 3

 THO complex subunit 3 ELISA Kit
 THO complex subunit 3 Recombinant
 THO complex subunit 3 Antibody
Also known as THO complex subunit 3 (TEX1 homolog) (AtTEX1).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO3 ELISA Kit
 THO3 Recombinant
 THO3 Antibody
 TEX1 ELISA Kit
 TEX1 Recombinant
 TEX1 Antibody
 At5g56130 ELISA Kit
 At5g56130 Recombinant
 At5g56130 Antibody
 MDA7.19 ELISA Kit
 MDA7.19 Recombinant
 MDA7.19 Antibody
Table BarTOPTable Bar
 

THO complex subunit 4

 THO complex subunit 4 ELISA Kit
 THO complex subunit 4 Recombinant
 THO complex subunit 4 Antibody
Also known as THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (REF1-I) (RNA and export factor-binding protein 1) (Transcriptional coactivator Aly/REF).
THOC4: a chaperone protein that promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains thus promoting transcriptional activation. Plays a role in mRNA processing and export. May function as scaffold that mediates interactions between proteins and/or RNA. Integral part of the THO/TREX complex that is recruited to transcribed genes and travels with the RNA polymerase dur
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ing elongation. Is part of the exon junction complex that remains associated with spliced mRNA and plays an important role in mRNA export and nonsense-mediated RNA decay. Nuclear localization, translocates to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Two differentially spliced isoforms have been described.

Protein type: Chaperone; RNA-binding; Spliceosome; Transcription, coactivator/corepressor

Cellular Component: nucleus

Molecular Function: RNA binding; single-stranded DNA binding
 Alyref ELISA Kit
 Alyref Recombinant
 Alyref Antibody
 Aly ELISA Kit
 Aly Recombinant
 Aly Antibody
 Ref1 ELISA Kit
 Ref1 Recombinant
 Ref1 Antibody
 Refbp1 ELISA Kit
 Refbp1 Recombinant
 Refbp1 Antibody
Table BarTOPTable Bar
 

THO complex subunit 4A

 THO complex subunit 4A ELISA Kit
 THO complex subunit 4A Recombinant
 THO complex subunit 4A Antibody
Also known as THO complex subunit 4A (ALYREF homolog 1) (AtALY1).
Export adapter involved in nuclear export of spliced and unspliced mRNA.
 ALY1 ELISA Kit
 ALY1 Recombinant
 ALY1 Antibody
 THO4A ELISA Kit
 THO4A Recombinant
 THO4A Antibody
 At5g59950 ELISA Kit
 At5g59950 Recombinant
 At5g59950 Antibody
 MMN10.26 ELISA Kit
 MMN10.26 Recombinant
 MMN10.26 Antibody
Table BarTOPTable Bar
 

THO complex subunit 4-A

 THO complex subunit 4-A ELISA Kit
 THO complex subunit 4-A Recombinant
 THO complex subunit 4-A Antibody
Also known as THO complex subunit 4-A (Tho4-A) (Aly/REF export factor-A).
Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spl
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iced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. Involved in the nuclear export of intronless mRNA. Involved in transcription elongation and genome stability ().
 alyref-a ELISA Kit
 alyref-a Recombinant
 alyref-a Antibody
 thoc4-a ELISA Kit
 thoc4-a Recombinant
 thoc4-a Antibody
Table BarTOPTable Bar
 

THO complex subunit 4B

 THO complex subunit 4B ELISA Kit
 THO complex subunit 4B Recombinant
 THO complex subunit 4B Antibody
Also known as THO complex subunit 4B (ALYREF homolog 2) (AtALY2).
Export adapter involved in nuclear export of spliced and unspliced mRNA.
 ALY2 ELISA Kit
 ALY2 Recombinant
 ALY2 Antibody
 THO4B ELISA Kit
 THO4B Recombinant
 THO4B Antibody
 At5g02530 ELISA Kit
 At5g02530 Recombinant
 At5g02530 Antibody
Table BarTOPTable Bar
 

THO complex subunit 4-B

 THO complex subunit 4-B ELISA Kit
 THO complex subunit 4-B Recombinant
 THO complex subunit 4-B Antibody
Also known as THO complex subunit 4-B (Tho4-B) (Aly/REF export factor-B).
Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spl
>>>
iced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. Involved in the nuclear export of intronless mRNA. Involved in transcription elongation and genome stability ().
 alyref-b ELISA Kit
 alyref-b Recombinant
 alyref-b Antibody
 thoc4-b ELISA Kit
 thoc4-b Recombinant
 thoc4-b Antibody
Table BarTOPTable Bar
 

THO complex subunit 4C

 THO complex subunit 4C ELISA Kit
 THO complex subunit 4C Recombinant
 THO complex subunit 4C Antibody
Also known as THO complex subunit 4C (ALYREF homolog 3) (AtALY3).
Export adapter involved in nuclear export of spliced and unspliced mRNA.
 ALY3 ELISA Kit
 ALY3 Recombinant
 ALY3 Antibody
 DIP1 ELISA Kit
 DIP1 Recombinant
 DIP1 Antibody
 THO4C ELISA Kit
 THO4C Recombinant
 THO4C Antibody
 At1g66260 ELISA Kit
 At1g66260 Recombinant
 At1g66260 Antibody
Table BarTOPTable Bar
 

THO complex subunit 4D

 THO complex subunit 4D ELISA Kit
 THO complex subunit 4D Recombinant
 THO complex subunit 4D Antibody
Also known as THO complex subunit 4D (ALYREF homolog 4) (AtALY4).
Export adapter involved in nuclear export of spliced and unspliced mRNA.
 ALY4 ELISA Kit
 ALY4 Recombinant
 ALY4 Antibody
 DIP2 ELISA Kit
 DIP2 Recombinant
 DIP2 Antibody
 THO4D ELISA Kit
 THO4D Recombinant
 THO4D Antibody
 At5g37720 ELISA Kit
 At5g37720 Recombinant
 At5g37720 Antibody
Table BarTOPTable Bar
 

THO complex subunit 5

 THO complex subunit 5 ELISA Kit
 THO complex subunit 5 Recombinant
 THO complex subunit 5 Antibody
The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress.
 thoc5 ELISA Kit
 thoc5 Recombinant
 thoc5 Antibody
 CG2980 ELISA Kit
 CG2980 Recombinant
 CG2980 Antibody
Table BarTOPTable Bar
 

THO complex subunit 5 homolog

 THO complex subunit 5 homolog ELISA Kit
 THO complex subunit 5 homolog Recombinant
 THO complex subunit 5 homolog Antibody
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-de
>>>
pendent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway ().
 THOC5 ELISA Kit
 THOC5 Recombinant
 THOC5 Antibody
 RCJMB04_17i18 ELISA Kit
 RCJMB04_17i18 Recombinant
 RCJMB04_17i18 Antibody
Table BarTOPTable Bar
 

THO complex subunit 5 homolog A

 THO complex subunit 5 homolog A ELISA Kit
 THO complex subunit 5 homolog A Recombinant
 THO complex subunit 5 homolog A Antibody
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-de
>>>
pendent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway ().
 thoc5-a ELISA Kit
 thoc5-a Recombinant
 thoc5-a Antibody
Table BarTOPTable Bar
 

THO complex subunit 5 homolog B

 THO complex subunit 5 homolog B ELISA Kit
 THO complex subunit 5 homolog B Recombinant
 THO complex subunit 5 homolog B Antibody
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-de
>>>
pendent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway ().
 thoc5-b ELISA Kit
 thoc5-b Recombinant
 thoc5-b Antibody
Table BarTOPTable Bar
 

THO complex subunit 5A

 THO complex subunit 5A ELISA Kit
 THO complex subunit 5A Recombinant
 THO complex subunit 5A Antibody
Also known as THO complex subunit 5A (THO complex subunit 5) (AtTHO5).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO5A ELISA Kit
 THO5A Recombinant
 THO5A Antibody
 THO5 ELISA Kit
 THO5 Recombinant
 THO5 Antibody
 THOC5B ELISA Kit
 THOC5B Recombinant
 THOC5B Antibody
 At1g45233 ELISA Kit
 At1g45233 Recombinant
 At1g45233 Antibody
Table BarTOPTable Bar
 

THO complex subunit 5B

 THO complex subunit 5B ELISA Kit
 THO complex subunit 5B Recombinant
 THO complex subunit 5B Antibody
Also known as THO complex subunit 5B (THO complex subunit 5) (AtTHO5).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO5B ELISA Kit
 THO5B Recombinant
 THO5B Antibody
 THO5 ELISA Kit
 THO5 Recombinant
 THO5 Antibody
 THOC5A ELISA Kit
 THOC5A Recombinant
 THOC5A Antibody
 At5g42920 ELISA Kit
 At5g42920 Recombinant
 At5g42920 Antibody
Table BarTOPTable Bar
 

THO complex subunit 6

 THO complex subunit 6 ELISA Kit
 THO complex subunit 6 Recombinant
 THO complex subunit 6 Antibody
The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress.
 thoc6 ELISA Kit
 thoc6 Recombinant
 thoc6 Antibody
 CG5632 ELISA Kit
 CG5632 Recombinant
 CG5632 Antibody
Table BarTOPTable Bar
 

THO complex subunit 6 homolog

 THO complex subunit 6 homolog ELISA Kit
 THO complex subunit 6 homolog Recombinant
 THO complex subunit 6 homolog Antibody
Also known as THO complex subunit 6 homolog (Functional spliceosome-associated protein 35) (fSAP35) (WD repeat-containing protein 58).
THOC6: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction bet
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ween ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4. Belongs to the WD repeat THOC6 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nuclear chromosome, telomeric region; nucleoplasm; nucleus

Biological Process: central nervous system development; intronless viral mRNA export from host nucleus; mRNA 3'-end processing; mRNA export from nucleus; negative regulation of apoptosis; RNA export from nucleus; termination of RNA polymerase II transcription

Disease: Beaulieu-boycott-innes Syndrome
 THOC6 ELISA Kit
 THOC6 Recombinant
 THOC6 Antibody
 WDR58 ELISA Kit
 WDR58 Recombinant
 WDR58 Antibody
 PSEC0006 ELISA Kit
 PSEC0006 Recombinant
 PSEC0006 Antibody
Table BarTOPTable Bar
 

THO complex subunit 7 homolog

 THO complex subunit 7 homolog ELISA Kit
 THO complex subunit 7 homolog Recombinant
 THO complex subunit 7 homolog Antibody
Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction com
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plex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.
 thoc7 ELISA Kit
 thoc7 Recombinant
 thoc7 Antibody
Table BarTOPTable Bar
 

THO complex subunit 7A

 THO complex subunit 7A ELISA Kit
 THO complex subunit 7A Recombinant
 THO complex subunit 7A Antibody
Also known as THO complex subunit 7A (THO complex subunit 7) (AtTHO7).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO7A ELISA Kit
 THO7A Recombinant
 THO7A Antibody
 THOC7B ELISA Kit
 THOC7B Recombinant
 THOC7B Antibody
 At5g16790 ELISA Kit
 At5g16790 Recombinant
 At5g16790 Antibody
 F5E19.130 ELISA Kit
 F5E19.130 Recombinant
 F5E19.130 Antibody
Table BarTOPTable Bar
 

THO complex subunit 7B

 THO complex subunit 7B ELISA Kit
 THO complex subunit 7B Recombinant
 THO complex subunit 7B Antibody
Also known as THO complex subunit 7B (THO complex subunit 7) (AtTHO7).
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
 THO7B ELISA Kit
 THO7B Recombinant
 THO7B Antibody
 THOC7A ELISA Kit
 THOC7A Recombinant
 THOC7A Antibody
 At3g02950 ELISA Kit
 At3g02950 Recombinant
 At3g02950 Antibody
 F13E7.10 ELISA Kit
 F13E7.10 Recombinant
 F13E7.10 Antibody
Table BarTOPTable Bar
 

THO complex subunit HPR1

 THO complex subunit HPR1 ELISA Kit
 THO complex subunit HPR1 Recombinant
 THO complex subunit HPR1 Antibody
Also known as THO complex subunit HPR1 (Hyperrecombination protein 1).
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by
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facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
 HPR1 ELISA Kit
 HPR1 Recombinant
 HPR1 Antibody
 YDR138W ELISA Kit
 YDR138W Recombinant
 YDR138W Antibody
 YD9302.14 ELISA Kit
 YD9302.14 Recombinant
 YD9302.14 Antibody
Table BarTOPTable Bar
 

THO complex subunit mft1

 THO complex subunit mft1 ELISA Kit
 THO complex subunit mft1 Recombinant
 THO complex subunit mft1 Antibody
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating
>>>
polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA ().
 mft1 ELISA Kit
 mft1 Recombinant
 mft1 Antibody
 SPCC24B10.11c ELISA Kit
 SPCC24B10.11c Recombinant
 SPCC24B10.11c Antibody
Table BarTOPTable Bar
 

THO complex subunit THP2

 THO complex subunit THP2 ELISA Kit
 THO complex subunit THP2 Recombinant
 THO complex subunit THP2 Antibody
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating
>>>
polymerase. It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
 THP2 ELISA Kit
 THP2 Recombinant
 THP2 Antibody
 YHR167W ELISA Kit
 YHR167W Recombinant
 YHR167W Antibody
Table BarTOPTable Bar
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