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Three-finger muscarinic toxin

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Shows a non-competitive interaction with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC(50)=2.3 nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B), and alpha-2c (ADRA2C) adrenergic receptors. Reversibly binds to M1 (CHRM1) muscarinic acetylcholine receptors, probably by interacting with the orthosteric site .

Below are the list of possible Three-finger muscarinic toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Three-finger muscarinic toxin 1

 Three-finger muscarinic toxin 1 ELISA Kit
 Three-finger muscarinic toxin 1 Recombinant
 Three-finger muscarinic toxin 1 Antibody
Also known as Three-finger muscarinic toxin 1 (MT1) (MTx1).
Shows a non-competitive interaction with adrenergic and muscarinic receptors. Binds to alpha-2b (ADRA2B) (IC50=2.3 nM), alpha-1a (ADRA1A)
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, alpha-1b (ADRA1B), and alpha-2c (ADRA2C) adrenergic receptors. Reversibly binds to M1 (CHRM1) muscarinic acetylcholine receptors, probably by interacting with the orthosteric site (PubMed:7778123, PubMed:12488533, PubMed:24793485). Also reveals a slightly weaker effect at M3 (CHRM3) (PubMed:7778123) and M4 (CHRM4) receptors (PubMed:12488533, PubMed:24793485). The order of potency is ADRA2B>>CHRM1>ADRA1A>ADRA1B>ADRA2C/CHRM4 (PubMed:24793485).
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Three-finger muscarinic toxin 7

 Three-finger muscarinic toxin 7 ELISA Kit
 Three-finger muscarinic toxin 7 Recombinant
 Three-finger muscarinic toxin 7 Antibody
Also known as Three-finger muscarinic toxin 7 (MT-7) (MT7) (Muscarinic m1-toxin 1).
Binds irreversibly and specifically to an allosteric site of the muscarinic acetylcholine M1 receptor (CHRM1).
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