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Thrombopoietin

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Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

Below are the list of possible Thrombopoietin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Thrombopoietin

 Thrombopoietin ELISA Kit
 Thrombopoietin Recombinant
 Thrombopoietin Antibody
THPO: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. Defects in THPO are the cause of thrombocythemia type 1 (THCYT1). A myeloproliferative disorder characterized by elevated platelet levels due to
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sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications. Belongs to the EPO/TPO family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide

Cellular Component: extracellular region

Molecular Function: receptor binding

Biological Process: myeloid cell differentiation; positive regulation of cell proliferation; positive regulation of megakaryocyte differentiation; positive regulation of protein amino acid phosphorylation; positive regulation of protein kinase B signaling cascade; response to lipopolysaccharide
 Thpo ELISA Kit
 Thpo Recombinant
 Thpo Antibody
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