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Thrombopoietin receptor

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Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses.

Below are the list of possible Thrombopoietin receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Thrombopoietin receptor

 Thrombopoietin receptor ELISA Kit
 Thrombopoietin receptor Recombinant
 Thrombopoietin receptor Antibody
Also known as Thrombopoietin receptor (TPO-R) (Myeloproliferative leukemia protein) (Proto-oncogene c-Mpl) (CD antigen CD110).
MPL: a hematopoietic receptor for thrombopoietin. Thrombopoietin is the major regulator of megakaryocytopoiesis and platelet formation. Dimerizes upon binding of thrombopoietin, leading to its phosphorylation and activation of JAKs and STATs. May represent a regulato
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ry molecule specific for TPO-R-dependent immune responses. Two splice-variant isoforms have been described.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 1p34

Cellular Component: cell surface; Golgi apparatus; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; transmembrane receptor activity

Biological Process: cell proliferation; cell surface receptor linked signal transduction

Disease: Amegakaryocytic Thrombocytopenia, Congenital; Myelofibrosis; Thrombocythemia 2
 MPL ELISA Kit
 MPL Recombinant
 MPL Antibody
 TPOR ELISA Kit
 TPOR Recombinant
 TPOR Antibody
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