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Thrombospondin

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Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).

Below are the list of possible Thrombospondin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Thrombospondin-1

 Thrombospondin-1 ELISA Kit
 Thrombospondin-1 Recombinant
 Thrombospondin-1 Antibody
THBS1: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties. Belongs to the thrombospondin family.

Protein type: Inhibitor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q15

Cellular Component: cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; external side of plasma membrane; extracellular matrix; extracellular region; extracellular space; fibrinogen complex;
>>>
sarcoplasmic reticulum; secretory granule

Molecular Function: fibroblast growth factor binding; fibronectin binding; heparin binding; integrin binding; laminin binding; low-density lipoprotein binding; phosphatidylserine binding; protein binding; proteoglycan binding; transforming growth factor beta binding

Biological Process: activation of MAPK activity; behavioral response to pain; cell cycle arrest; cell migration; chronic inflammatory response; engulfment of apoptotic cell; extracellular matrix organization and biogenesis; immune response; inflammatory response; negative regulation of angiogenesis; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; negative regulation of apoptosis; negative regulation of blood vessel endothelial cell migration; negative regulation of caspase activity; negative regulation of cell-matrix adhesion; negative regulation of dendritic cell antigen processing and presentation; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of focal adhesion formation; negative regulation of interleukin-12 production; peptide cross-linking; platelet degranulation; positive regulation of angiogenesis; positive regulation of blood coagulation; positive regulation of blood vessel endothelial cell migration; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of chemotaxis; positive regulation of macrophage activation; positive regulation of phosphorylation; positive regulation of protein kinase B signaling cascade; positive regulation of smooth muscle cell proliferation; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of transforming growth factor-beta1 production; positive regulation of translation; positive regulation of tumor necrosis factor biosynthetic process; regulation of cGMP metabolic process; response to calcium ion; response to drug; response to glucose stimulus; response to magnesium ion; response to progesterone stimulus; sprouting angiogenesis
 THBS1 ELISA Kit
 THBS1 Recombinant
 THBS1 Antibody
 TSP ELISA Kit
 TSP Recombinant
 TSP Antibody
 TSP1 ELISA Kit
 TSP1 Recombinant
 TSP1 Antibody
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Thrombospondin-2

 Thrombospondin-2 ELISA Kit
 Thrombospondin-2 Recombinant
 Thrombospondin-2 Antibody
THBS2: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD); also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral
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leg pain. Belongs to the thrombospondin family.

Protein type: Motility/polarity/chemotaxis

Cellular Component: basement membrane; proteinaceous extracellular matrix

Molecular Function: protein binding

Biological Process: negative regulation of angiogenesis; positive regulation of synaptogenesis
 Thbs2 ELISA Kit
 Thbs2 Recombinant
 Thbs2 Antibody
 Tsp2 ELISA Kit
 Tsp2 Recombinant
 Tsp2 Antibody
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Thrombospondin-3

 Thrombospondin-3 ELISA Kit
 Thrombospondin-3 Recombinant
 Thrombospondin-3 Antibody
THBS3: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Belongs to the thrombospondin family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extracellular region; perinuclear region of cytoplasm

Molecular Functio
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n: heparin binding
 THBS3 ELISA Kit
 THBS3 Recombinant
 THBS3 Antibody
 TSP3 ELISA Kit
 TSP3 Recombinant
 TSP3 Antibody
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Thrombospondin-3a

 Thrombospondin-3a ELISA Kit
 Thrombospondin-3a Recombinant
 Thrombospondin-3a Antibody
Also known as Thrombospondin-3a (Thbs3a).
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen ().
 thbs3a ELISA Kit
 thbs3a Recombinant
 thbs3a Antibody
 thbs3 ELISA Kit
 thbs3 Recombinant
 thbs3 Antibody
 tsp3 ELISA Kit
 tsp3 Recombinant
 tsp3 Antibody
 zgc:103461 ELISA Kit
 zgc:103461 Recombinant
 zgc:103461 Antibody
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Thrombospondin-3b

 Thrombospondin-3b ELISA Kit
 Thrombospondin-3b Recombinant
 Thrombospondin-3b Antibody
Also known as Thrombospondin-3b (Thbs3b).
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen ().
 thbs3b ELISA Kit
 thbs3b Recombinant
 thbs3b Antibody
 si:dkey-81h8.2 ELISA Kit
 si:dkey-81h8.2 Recombinant
 si:dkey-81h8.2 Antibody
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Thrombospondin-4

 Thrombospondin-4 ELISA Kit
 Thrombospondin-4 Recombinant
 Thrombospondin-4 Antibody
THBS4: Acts as an extracellular mitogen and stimulates early erythroid progenitors proliferation in presence of EPO. Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Belongs to the thrombospondin family.

Protein type: Motility/polarity/chemotaxis

Cellular Component: basement membrane; endoplasmic reticulum; extracellular matrix; extracellular space; neuromuscular junction; proteinaceous extracellular matrix; sarcoplasmic reticulum

Molecular Function: calcium ion binding; coll
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agen binding; fibronectin binding; heparin binding; integrin binding; laminin-1 binding

Biological Process: behavioral response to pain; myoblast migration; negative regulation of angiogenesis; nervous system development; neurite morphogenesis; positive regulation of endothelial cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; protein homooligomerization; regulation of tissue remodeling
 Thbs4 ELISA Kit
 Thbs4 Recombinant
 Thbs4 Antibody
 Tsp-4 ELISA Kit
 Tsp-4 Recombinant
 Tsp-4 Antibody
 Tsp4 ELISA Kit
 Tsp4 Recombinant
 Tsp4 Antibody
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Thrombospondin-4-B

 Thrombospondin-4-B ELISA Kit
 Thrombospondin-4-B Recombinant
 Thrombospondin-4-B Antibody
Also known as Thrombospondin-4-B (Thbs4-B).
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and may be involved in various processes including cellular proliferation, migration, adhesion and attachment. May play a role in ER stress response ().
 thbs4b ELISA Kit
 thbs4b Recombinant
 thbs4b Antibody
 thbs4 ELISA Kit
 thbs4 Recombinant
 thbs4 Antibody
 tsp4 ELISA Kit
 tsp4 Recombinant
 tsp4 Antibody
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