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Thyroid receptor-interacting protein

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Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.

Below are the list of possible Thyroid receptor-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Thyroid receptor-interacting protein 11

 Thyroid receptor-interacting protein 11 ELISA Kit
 Thyroid receptor-interacting protein 11 Recombinant
 Thyroid receptor-interacting protein 11 Antibody
Also known as Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230).
TRIP11: Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB- modulated transcription. Golgi auto-antigen; prob
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ably involved in maintaining cis-Golgi structure. A chromosomal aberration involving TRIP11 may be a cause of acute myelogenous leukemia. Translocation t(5;14)(q33;q32) with PDGFRB. The fusion protein may be involved in clonal evolution of leukemia and eosinophilia. Defects in TRIP11 are the cause of achondrogenesis type 1A (ACG1A). A form of achondrogenesis type 1, a lethal form of chondrodysplasia characterized by deficient ossification in the lumbar vertebrae and absent ossification in the sacral, pubic and ischial bones and clinically by stillbirth or early death. In addition to severe micromelia, there is a disproportionately large cranium due to marked edema of soft tissues.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 14q31-q32

Cellular Component: Golgi apparatus; Golgi membrane; nucleus; transport vesicle

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter

Disease: Achondrogenesis, Type Ia
 TRIP11 ELISA Kit
 TRIP11 Recombinant
 TRIP11 Antibody
 CEV14 ELISA Kit
 CEV14 Recombinant
 CEV14 Antibody
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Thyroid receptor-interacting protein 6

 Thyroid receptor-interacting protein 6 ELISA Kit
 Thyroid receptor-interacting protein 6 Recombinant
 Thyroid receptor-interacting protein 6 Antibody
Also known as Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6).
Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrep
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ression of these transcription factors induced by glucocorticoid receptor ().
 TRIP6 ELISA Kit
 TRIP6 Recombinant
 TRIP6 Antibody
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