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Tissue-resident T-cell transcription regulator protein

Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Plays also a role in the differentiation of both thymic and peripheral NKT cells. Negatively regulates the accumulation of interferon-gamma (IFN-gamma) in NKT cells at steady state or after antigenic stimulation. Positively regulates granzyme B production in NKT cells after innate stimulation. Associates with the transcriptional repressor PRDM1/BLIMP1 to chromatin at gene promoter regions.

Below are the list of possible Tissue-resident T-cell transcription regulator protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Tissue-resident T-cell transcription regulator protein ZNF683

 Tissue-resident T-cell transcription regulator protein ZNF683 ELISA Kit
 Tissue-resident T-cell transcription regulator protein ZNF683 Recombinant
 Tissue-resident T-cell transcription regulator protein ZNF683 Antibody
Also known as Tissue-resident T-cell transcription regulator protein ZNF683 (Homolog of Blimp-1 in T-cell) (Hobit) (Zinc finger protein 683).
ZNF683: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

l Location of Human Ortholog: 1p36.11

Biological Process: regulation of extrathymic T cell differentiation; regulation of gene expression; regulation of natural killer cell differentiation; regulation of natural killer cell differentiation during immune response; regulation of NK T cell differentiation
 ZNF683 Recombinant
 ZNF683 Antibody
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