Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow TNFAIP3-interacting protein  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Growth Differentiation Factor 6 (GDF6) ELISA Kit
 • IgG Antibody
 • AVPR1A Antibody
 • 3-oxoacyl-[acyl-carrier-pro tein] reductase FabG (fabG) Recombinant Protein
 • G Protein Coupled Receptor, Family C, Group 5, Member A (GPR... ELISA Kit
 • Peptide YY (PYY) Antibody
 • Vaccinia Virus (Lister Strain) Antibody
 • INPP5E Antibody
 • A disintegrin and metalloproteinase with thrombospondin moti... ELISA Kit
 • AP2 alpha (TFAP2A) Antibody
 • selenoprotein N, 1 (SEPN1) ELISA Kit
 • B-cell antigen receptor complex-associated protein alpha cha... Recombinant Protein
 • AREG Antibody
 • CD45 - LCA (PTPRC) Antibody
 downarrow more ...
separator

TNFAIP3-interacting protein

separator
Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases.

Below are the list of possible TNFAIP3-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

TNFAIP3-interacting protein 1

 TNFAIP3-interacting protein 1 ELISA Kit
 TNFAIP3-interacting protein 1 Recombinant
 TNFAIP3-interacting protein 1 Antibody
Also known as TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN) (ABIN-1) (Nef-associated factor 1) (Naf1) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).
TNIP1: Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal; however, binding to A20/TNFAIP3 seems not to be required for this function. Inhibits NF-kappa-B activation by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiqui
>>>
tinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcricption. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflamation; this function is mediated by association with SELPLG and dependent on phosohorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection. Interacts with TNFAIP3 and IKBKG; facilitates TNFAIP3- mediated de-ubiquitination of NEMO/IKBKG. Interacts with HIV-1 matrix protein. Interacts with Shigella flexneri ipah9.8; the interaction promotes polyubiquitination of IKBKG. Interacts with polyubiquitin. Interacts with MAPK1, SELPLG and PIK3CD. Interacts with IKBKG (polyubiquitinated). Interacts with IRAK1 (polyubiquitinated). Interacts with MYD88; the interaction is indicative for participation in an activated TLR-signaling complex. Ubiquitous. Strongly expressed in peripheral blood lymphocytes, spleen and skeletal muscle, and is weakly expressed in the brain. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: mitogen-activated protein kinase binding; polyubiquitin binding; ubiquitin-specific protease activity

Biological Process: glycoprotein biosynthetic process; leukocyte adhesion; MyD88-dependent toll-like receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of inflammatory response; positive regulation of transcription from RNA polymerase II promoter
 Tnip1 ELISA Kit
 Tnip1 Recombinant
 Tnip1 Antibody
 Abin ELISA Kit
 Abin Recombinant
 Abin Antibody
 Naf1 ELISA Kit
 Naf1 Recombinant
 Naf1 Antibody
Table BarTOPTable Bar
 

TNFAIP3-interacting protein 2

 TNFAIP3-interacting protein 2 ELISA Kit
 TNFAIP3-interacting protein 2 Recombinant
 TNFAIP3-interacting protein 2 Antibody
Also known as TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2).
TNIP2: Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation
>>>
of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: polyubiquitin binding; protein binding; protein kinase binding

Biological Process: I-kappaB kinase/NF-kappaB cascade; positive regulation of B cell activation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of macrophage activation; positive regulation of transcription from RNA polymerase II promoter; protein stabilization; toll-like receptor 2 signaling pathway; toll-like receptor 3 signaling pathway; toll-like receptor 9 signaling pathway
 Tnip2 ELISA Kit
 Tnip2 Recombinant
 Tnip2 Antibody
 Abin2 ELISA Kit
 Abin2 Recombinant
 Abin2 Antibody
Table BarTOPTable Bar
 

TNFAIP3-interacting protein 3

 TNFAIP3-interacting protein 3 ELISA Kit
 TNFAIP3-interacting protein 3 Recombinant
 TNFAIP3-interacting protein 3 Antibody
Also known as TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein).
TNIP3: Binds to zinc finger protein TNFAIP3 and inhibits NF- kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13- acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Protein type: Inhibitor

Chromosomal Loca
>>>
tion of Human Ortholog: 4q27

Molecular Function: polyubiquitin binding; protein binding

Biological Process: MyD88-independent toll-like receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 4 signaling pathway
 TNIP3 ELISA Kit
 TNIP3 Recombinant
 TNIP3 Antibody
 ABIN3 ELISA Kit
 ABIN3 Recombinant
 ABIN3 Antibody
 LIND ELISA Kit
 LIND Recombinant
 LIND Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions