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Torsin

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Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In the nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues (By similarity).

Below are the list of possible Torsin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Torsin-1A

 Torsin-1A ELISA Kit
 Torsin-1A Recombinant
 Torsin-1A Antibody
Also known as Torsin-1A (Dystonia 1 protein) (Torsin ATPase 1).
Protein with chaperone functions important for the control of protein folding, processing, stability and localization as well as for the reduction of misfolded protein aggregates. Involved in the regulation of synaptic vesicle recycling, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN). In t
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he nucleus, may link the cytoskeleton with the nuclear envelope, this mechanism seems to be crucial for the control of nuclear polarity, cell movement and, specifically in neurons, nuclear envelope integrity. Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, leading to the modulation of dopamine neurotransmission. In the endoplasmic reticulum, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding. May have a redundant function with TOR1B in non-neural tissues ().
 Tor1a ELISA Kit
 Tor1a Recombinant
 Tor1a Antibody
 Dyt1 ELISA Kit
 Dyt1 Recombinant
 Dyt1 Antibody
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Torsin-1B

 Torsin-1B ELISA Kit
 Torsin-1B Recombinant
 Torsin-1B Antibody
Also known as Torsin-1B (Torsin ATPase-1B) (Torsin family 1 member B).
TOR1B: May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Belongs to the clpA/clpB family. Torsin subfamily.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; nuclear envelope

Molecular Function: ATPase activity; protein binding

Biological Process: endoplasmic reticulum organization and biogenesis; protein homooligomeri
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zation; response to unfolded protein
 TOR1B ELISA Kit
 TOR1B Recombinant
 TOR1B Antibody
 DQ1 ELISA Kit
 DQ1 Recombinant
 DQ1 Antibody
 FKSG18 ELISA Kit
 FKSG18 Recombinant
 FKSG18 Antibody
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Torsin-2A

 Torsin-2A ELISA Kit
 Torsin-2A Recombinant
 Torsin-2A Antibody
Also known as Torsin-2A (Torsin family 2 member A).
 TOR2A ELISA Kit
 TOR2A Recombinant
 TOR2A Antibody
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Torsin-3A

 Torsin-3A ELISA Kit
 Torsin-3A Recombinant
 Torsin-3A Antibody
Also known as Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A).
TOR3A: Belongs to the clpA/clpB family. Torsin subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen

Molecular Function: ATPase activity; protein binding
 Tor3a ELISA Kit
 Tor3a Recombinant
 Tor3a Antibody
 Adir ELISA Kit
 Adir Recombinant
 Adir Antibody
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Torsin-4A

 Torsin-4A ELISA Kit
 Torsin-4A Recombinant
 Torsin-4A Antibody
Also known as Torsin-4A (Torsin family 4 member A).
 tor4a ELISA Kit
 tor4a Recombinant
 tor4a Antibody
 zgc:110567 ELISA Kit
 zgc:110567 Recombinant
 zgc:110567 Antibody
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Torsin-4A-A

 Torsin-4A-A ELISA Kit
 Torsin-4A-A Recombinant
 Torsin-4A-A Antibody
Also known as Torsin-4A-A (Torsin family 4 member A-A).
 tor4a-a ELISA Kit
 tor4a-a Recombinant
 tor4a-a Antibody
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Torsin-4A-B

 Torsin-4A-B ELISA Kit
 Torsin-4A-B Recombinant
 Torsin-4A-B Antibody
Also known as Torsin-4A-B (Torsin family 4 member A-B).
 tor4a-b ELISA Kit
 tor4a-b Recombinant
 tor4a-b Antibody
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Proteins Root Name Listing
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