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Toxin

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Below are the list of possible Toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Toxin 3FTx-Dis4

 Toxin 3FTx-Dis4 ELISA Kit
 Toxin 3FTx-Dis4 Recombinant
 Toxin 3FTx-Dis4 Antibody
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Toxin 3FTx-Lei1

 Toxin 3FTx-Lei1 ELISA Kit
 Toxin 3FTx-Lei1 Recombinant
 Toxin 3FTx-Lei1 Antibody
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Toxin 3FTx-Oxy5

 Toxin 3FTx-Oxy5 ELISA Kit
 Toxin 3FTx-Oxy5 Recombinant
 Toxin 3FTx-Oxy5 Antibody
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Toxin 3FTx-Oxy6

 Toxin 3FTx-Oxy6 ELISA Kit
 Toxin 3FTx-Oxy6 Recombinant
 Toxin 3FTx-Oxy6 Antibody
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Toxin 3FTx-Psa1

 Toxin 3FTx-Psa1 ELISA Kit
 Toxin 3FTx-Psa1 Recombinant
 Toxin 3FTx-Psa1 Antibody
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Toxin 3FTx-Tel4

 Toxin 3FTx-Tel4 ELISA Kit
 Toxin 3FTx-Tel4 Recombinant
 Toxin 3FTx-Tel4 Antibody
Potent postsynaptic neurotoxin. Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
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Toxin 3FTx-Thr5

 Toxin 3FTx-Thr5 ELISA Kit
 Toxin 3FTx-Thr5 Recombinant
 Toxin 3FTx-Thr5 Antibody
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Toxin 3FTx-Tri2

 Toxin 3FTx-Tri2 ELISA Kit
 Toxin 3FTx-Tri2 Recombinant
 Toxin 3FTx-Tri2 Antibody
Potent postsynaptic neurotoxin. Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
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Toxin 3FTx-Tri3

 Toxin 3FTx-Tri3 ELISA Kit
 Toxin 3FTx-Tri3 Recombinant
 Toxin 3FTx-Tri3 Antibody
Potent postsynaptic neurotoxin. Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
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Toxin 4.9.6

 Toxin 4.9.6 ELISA Kit
 Toxin 4.9.6 Recombinant
 Toxin 4.9.6 Antibody
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Toxin 5

 Toxin 5 ELISA Kit
 Toxin 5 Recombinant
 Toxin 5 Antibody
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
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Toxin a

 Toxin a ELISA Kit
 Toxin a Recombinant
 Toxin a Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Aah4

 Toxin Aah4 ELISA Kit
 Toxin Aah4 Recombinant
 Toxin Aah4 Antibody
Also known as Toxin Aah4 (AaH IV) (AaHIV) (Neurotoxin 4) (Neurotoxin IV).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated ch
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annels, thereby blocking neuronal transmission.
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Toxin Aah6

 Toxin Aah6 ELISA Kit
 Toxin Aah6 Recombinant
 Toxin Aah6 Antibody
Also known as Toxin Aah6 (AaH VI) (AaHVI) (Neurotoxin 6) (Neurotoxin VI).
Beta toxins bind voltage-independently at site-4 of sodium channels and shift the voltage of activation toward more negativ
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e potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on insects (). This toxin has very low anti-insect activity.
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Toxin AaHIT4

 Toxin AaHIT4 ELISA Kit
 Toxin AaHIT4 Recombinant
 Toxin AaHIT4 Antibody
Also known as Toxin AaHIT4 (AaH IT4) (AaIT4) (Insect toxin 4).
Has a toxic effect on insects and mammals and is capable of competing with anti-insect scorpion toxins for binding to the sodium chann
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el (Nav) of insects. It also modulates the binding of alpha-type and beta-type anti-mammal scorpion toxins to the mammal sodium channel.
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Toxin AahP1005

 Toxin AahP1005 ELISA Kit
 Toxin AahP1005 Recombinant
 Toxin AahP1005 Antibody
Also known as Toxin AahP1005 (Neurotoxin pcD-1005).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocki
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ng neuronal transmission.
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Toxin AahP985

 Toxin AahP985 ELISA Kit
 Toxin AahP985 Recombinant
 Toxin AahP985 Antibody
Also known as Toxin AahP985 (Neurotoxin pcD-985).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal t
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ransmission.
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Toxin Aam1

 Toxin Aam1 ELISA Kit
 Toxin Aam1 Recombinant
 Toxin Aam1 Antibody
Also known as Toxin Aam1 (AamH1) (Alpha-neurotoxin 1).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
 H1 ELISA Kit
 H1 Recombinant
 H1 Antibody
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Toxin Aam2

 Toxin Aam2 ELISA Kit
 Toxin Aam2 Recombinant
 Toxin Aam2 Antibody
Also known as Toxin Aam2 (AamH2) (Alpha-neurotoxin 2).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blo
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cking neuronal transmission.
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Toxin Aam3

 Toxin Aam3 ELISA Kit
 Toxin Aam3 Recombinant
 Toxin Aam3 Antibody
Also known as Toxin Aam3 (AamH3) (Alpha-neurotoxin 3).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
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Toxin Acra I-2

 Toxin Acra I-2 ELISA Kit
 Toxin Acra I-2 Recombinant
 Toxin Acra I-2 Antibody
Also known as Toxin Acra I-2 (Acra1).
Probable neurotoxin that inhibits ion channels (). Is toxic to mice. Is about 2.8% of the total protein in the venom.
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Toxin Acra I-3

 Toxin Acra I-3 ELISA Kit
 Toxin Acra I-3 Recombinant
 Toxin Acra I-3 Antibody
Probable neurotoxin that inhibits ion channels (). Is toxic to mice.
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Toxin Acra II-1

 Toxin Acra II-1 ELISA Kit
 Toxin Acra II-1 Recombinant
 Toxin Acra II-1 Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Acra II-2

 Toxin Acra II-2 ELISA Kit
 Toxin Acra II-2 Recombinant
 Toxin Acra II-2 Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Acra II-3

 Toxin Acra II-3 ELISA Kit
 Toxin Acra II-3 Recombinant
 Toxin Acra II-3 Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Acra III-1

 Toxin Acra III-1 ELISA Kit
 Toxin Acra III-1 Recombinant
 Toxin Acra III-1 Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Acra III-2

 Toxin Acra III-2 ELISA Kit
 Toxin Acra III-2 Recombinant
 Toxin Acra III-2 Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Acra1

 Toxin Acra1 ELISA Kit
 Toxin Acra1 Recombinant
 Toxin Acra1 Antibody
Also known as Toxin Acra1 (Acra I-1).
Probable neurotoxin that inhibits ion channels (). Is toxic to mice. Is about 2.8% of the total protein in the venom.
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Toxin Acra2

 Toxin Acra2 ELISA Kit
 Toxin Acra2 Recombinant
 Toxin Acra2 Antibody
Excitatory insect toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affe
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cting sodium channel activation and promoting spontaneous and repetitive firing (). Is lethal to mice. Is about 1% of the total protein in the venom.
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Toxin Acra3

 Toxin Acra3 ELISA Kit
 Toxin Acra3 Recombinant
 Toxin Acra3 Antibody
The molecular target of Acra3 remains undiscovered. In vivo, induces severe neurotoxic events in mice such as excitability and convulsions, leading to the death of the animals within a few minutes aft
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er injection. Does not show toxicity in insects and crustaceans (PubMed:22819772). Exerts very strong cytotoxic effect on a mouse brain tumor cell line (BC3H1) with an IC50 value of 5 mg/ml. It exerts its effects by inducing a stronger necrosis than apoptosis in BC3H1 cells (PubMed:24055552).
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Toxin Ado1

 Toxin Ado1 ELISA Kit
 Toxin Ado1 Recombinant
 Toxin Ado1 Antibody
Binds reversibly and blocks P/Q-type voltage-gated calcium channels (Cav).
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Toxin AdTx1

 Toxin AdTx1 ELISA Kit
 Toxin AdTx1 Recombinant
 Toxin AdTx1 Antibody
Also known as Toxin AdTx1 (Rho-elapitoxin-Da1a) (Rho-EPTX-Da1a).
Orthosteric antagonist of the alpha-1A adrenergic receptor (ADRA1A) with an affinity of 0.35 nM (PubMed:20015090). Has also affinity
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for ADRA1B > ADRA2C > ADRA1D (PubMed:23935897). Acts as a relaxant of smooth muscle. Reduces prostatic muscle tone as efficiently as tamsulosin (an antagonist presently used), but with fewer cardiovascular side effects (PubMed:23005263).
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Toxin Afp18

 Toxin Afp18 ELISA Kit
 Toxin Afp18 Recombinant
 Toxin Afp18 Antibody
Also known as Toxin Afp18 (Antifeeding prophage 18) (Antifeeding protein 18).
Toxin component of the prophage tail-derived protein translocation system Afp, which is the causative agent of enteric redmouth disease in salmonid fish species. Mono-O-GlcNAcylates the small GTPase RhoA in eukaryotic host cells at Tyr-34, using UDP-N-acetylglucosamine (UDP-GlcNAc) as the sugar donor. Glycosylation of RhoA results in impaired effector and regulator interaction and inactivation of downstream RhoA signaling which leads to actin filament depolymerization and blocks cytokinesis and gastrulation during
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zebrafish embryo development. To a lesser extent, is also able to glycosylate other Rho family GTPases (RhoB, RhoC, Rac1, Rac2, Rac3, and Cdc42) in vitro at a switch I tyrosine residue, but not Ras proteins.
 afp18 ELISA Kit
 afp18 Recombinant
 afp18 Antibody
 DJ39_2720 ELISA Kit
 DJ39_2720 Recombinant
 DJ39_2720 Antibody
 yruck0001_1570 ELISA Kit
 yruck0001_1570 Recombinant
 yruck0001_1570 Antibody
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Toxin B

 Toxin B ELISA Kit
 Toxin B Recombinant
 Toxin B Antibody
Cytotoxin.
 toxB ELISA Kit
 toxB Recombinant
 toxB Antibody
 tcdB ELISA Kit
 tcdB Recombinant
 tcdB Antibody
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Toxin b subunit alpha

 Toxin b subunit alpha ELISA Kit
 Toxin b subunit alpha Recombinant
 Toxin b subunit alpha Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin b subunit beta

 Toxin b subunit beta ELISA Kit
 Toxin b subunit beta Recombinant
 Toxin b subunit beta Antibody
Binds to sodium channels (Nav) and affects the channel activation process.
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Toxin Bcg III 15.67

 Toxin Bcg III 15.67 ELISA Kit
 Toxin Bcg III 15.67 Recombinant
 Toxin Bcg III 15.67 Antibody
Has both toxic and EGF activity.
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Toxin Bcg III 21.00

 Toxin Bcg III 21.00 ELISA Kit
 Toxin Bcg III 21.00 Recombinant
 Toxin Bcg III 21.00 Antibody
Also known as Toxin Bcg III 21.00 (Bcg 21.00) (AnmTX BC 9a-2).
Possible voltage-gated potassium channel (Kv) blocker.
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Toxin Bcg III 23.41

 Toxin Bcg III 23.41 ELISA Kit
 Toxin Bcg III 23.41 Recombinant
 Toxin Bcg III 23.41 Antibody
Also known as Toxin Bcg III 23.41 (Bcg 23.41) (AnmTX BC 9a-1).
Possible voltage-gated potassium channel (Kv) blocker. Increases amplitude and duration of crab leg nerve compound action potential.
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Toxin Bcg III 25.52

 Toxin Bcg III 25.52 ELISA Kit
 Toxin Bcg III 25.52 Recombinant
 Toxin Bcg III 25.52 Antibody
Also known as Toxin Bcg III 25.52 (Toxin Bcg 25.52).
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Toxin Bcg III 28.78

 Toxin Bcg III 28.78 ELISA Kit
 Toxin Bcg III 28.78 Recombinant
 Toxin Bcg III 28.78 Antibody
Also known as Toxin Bcg III 28.78 (Toxin Bcg 28.78).
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Toxin Bcg III 29.21

 Toxin Bcg III 29.21 ELISA Kit
 Toxin Bcg III 29.21 Recombinant
 Toxin Bcg III 29.21 Antibody
Also known as Toxin Bcg III 29.21 (Toxin Bcg 29.21).
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Toxin Bcg III 31.16

 Toxin Bcg III 31.16 ELISA Kit
 Toxin Bcg III 31.16 Recombinant
 Toxin Bcg III 31.16 Antibody
Also known as Toxin Bcg III 31.16 (Toxin Bcg 31.16).
Possible modulator of crustacean voltage-gated sodium channels (Nav).
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Toxin Bcs III 15.09

 Toxin Bcs III 15.09 ELISA Kit
 Toxin Bcs III 15.09 Recombinant
 Toxin Bcs III 15.09 Antibody
Has both toxic and EGF activity.
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Toxin BcV

 Toxin BcV ELISA Kit
 Toxin BcV Recombinant
 Toxin BcV Antibody
Potently and reversibly blocks mammalian Kv11/KCNH/ERG voltage-gated potassium channels. Acts as a gating-modifier toxin that shifts the voltage-dependence of ERG activation in the positive direction
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and suppresses its current amplitudes elicited by strong depolarizing pulses that maximally activate the channels.
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Toxin BeI2

 Toxin BeI2 ELISA Kit
 Toxin BeI2 Recombinant
 Toxin BeI2 Antibody
Also known as Toxin BeI2 (Insectotoxin I2).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active on i
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nsects.
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Toxin BeM14

 Toxin BeM14 ELISA Kit
 Toxin BeM14 Recombinant
 Toxin BeM14 Antibody
Also known as Toxin BeM14 (Neurotoxin M14).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuro
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nal transmission (). Has paralytic activity in mice.
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Toxin BmCa-1

 Toxin BmCa-1 ELISA Kit
 Toxin BmCa-1 Recombinant
 Toxin BmCa-1 Antibody
Also known as Toxin BmCa-1 (Calcium channel toxin BmCa1).
Putative ryanodine receptor inhibitor (RYR). May also inhibits potassium channels.
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Toxin BmKa1

 Toxin BmKa1 ELISA Kit
 Toxin BmKa1 Recombinant
 Toxin BmKa1 Antibody
Also known as Toxin BmKa1 (Alpha-toxin 1) (BmKalpha1).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blo
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cking neuronal transmission.
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Toxin BmKa3

 Toxin BmKa3 ELISA Kit
 Toxin BmKa3 Recombinant
 Toxin BmKa3 Antibody
Also known as Toxin BmKa3 (Alpha-toxin 3) (BmKalpha3).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blo
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cking neuronal transmission.
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Toxin BmKAEP

 Toxin BmKAEP ELISA Kit
 Toxin BmKAEP Recombinant
 Toxin BmKAEP Antibody
Also known as Toxin BmKAEP (Anti-epilepsy peptide) (BmK AEP).
Shows anti-epileptic activity. Shares high homology with depressant insect toxins, but shows very weak toxicity against mammals and ins
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ects and no obvious symptoms on insect larvae. May target voltage-gated sodium channel (Nav).
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Toxin BmKaIT1

 Toxin BmKaIT1 ELISA Kit
 Toxin BmKaIT1 Recombinant
 Toxin BmKaIT1 Antibody
Also known as Toxin BmKaIT1 (BmKalphaIT1) (Alpha-neurotoxin IT01) (Alpha-neurotoxin TX12) (BmKalphaIT01) (BmKalphaTx12).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) a
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nd inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (). Shows a high toxicity toward insects and moderate toxicity against mammals.
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Toxin BmKaTx10

 Toxin BmKaTx10 ELISA Kit
 Toxin BmKaTx10 Recombinant
 Toxin BmKaTx10 Antibody
Also known as Toxin BmKaTx10 (Alpha-neurotoxin Tx10) (BmKalphaTx10) (Toxin KT2).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal tr
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ansmission.
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Toxin BmKaTx13

 Toxin BmKaTx13 ELISA Kit
 Toxin BmKaTx13 Recombinant
 Toxin BmKaTx13 Antibody
Also known as Toxin BmKaTx13 (Alpha-neurotoxin Tx13) (BmKalphaTx13).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
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This toxin is active against mammals ().
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Toxin BmKaTX15

 Toxin BmKaTX15 ELISA Kit
 Toxin BmKaTX15 Recombinant
 Toxin BmKaTX15 Antibody
Also known as Toxin BmKaTX15 (Alpha-neurotoxin Tx15) (BmKalphaTx15) (KTc) (Na+ channel toxin BmKT').
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inact
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ivation of the activated channels, thereby blocking neuronal transmission.
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Toxin BmKaTx16

 Toxin BmKaTx16 ELISA Kit
 Toxin BmKaTx16 Recombinant
 Toxin BmKaTx16 Antibody
Also known as Toxin BmKaTx16 (Alpha-neurotoxin Tx16) (BmKalphaTx16).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby
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blocking neuronal transmission.
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Toxin BmKaTx17

 Toxin BmKaTx17 ELISA Kit
 Toxin BmKaTx17 Recombinant
 Toxin BmKaTx17 Antibody
Also known as Toxin BmKaTx17 (Alpha-neurotoxin Tx17) (BmKalphaTx17).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channel
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s, thereby blocking neuronal transmission.
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Toxin BmKBT

 Toxin BmKBT ELISA Kit
 Toxin BmKBT Recombinant
 Toxin BmKBT Antibody
Also known as Toxin BmKBT (BmK BT) (BmKabT) (BmK abT).
This toxin increases the peak sodium current, slows down the inactivation of sodium channels (Nav), and prolongs the action potential of dorsa
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l root ganglion neurons, which indicates that it behaves as a classical alpha-toxin. It binds to mammal brain and insect sodium channels, but with a different manner. This peptide may bind to a distinct receptor site on mammal brain sodium channels, which is unconnected with that for BmKAS (a beta-toxin), BmKIT2 (a beta-toxin) or BmK I (an alpha toxin). In contrast, the receptor site for BmKabT on insect sodium channels might be closely related to that for the beta-insect depressant toxin BmKIT2. Possess potent toxicity in mice but induces only paralysis in cotton bollworm.
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Toxin BmKIT3

 Toxin BmKIT3 ELISA Kit
 Toxin BmKIT3 Recombinant
 Toxin BmKIT3 Antibody
Also known as Toxin BmKIT3 (BmK IT3) (Insect toxin 3).
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at
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site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ().
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Toxin BmKITc

 Toxin BmKITc ELISA Kit
 Toxin BmKITc Recombinant
 Toxin BmKITc Antibody
Also known as Toxin BmKITc (BmK ITc).
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at site-4 of sodium
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channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ().
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Toxin BmKK12

 Toxin BmKK12 ELISA Kit
 Toxin BmKK12 Recombinant
 Toxin BmKK12 Antibody
Blocker of potassium channels (Kv).
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Toxin BmKK16

 Toxin BmKK16 ELISA Kit
 Toxin BmKK16 Recombinant
 Toxin BmKK16 Antibody
Blocker of potassium channels (Kv).
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Toxin BmKNJX11

 Toxin BmKNJX11 ELISA Kit
 Toxin BmKNJX11 Recombinant
 Toxin BmKNJX11 Antibody
Inhibits tetrodotoxin-sensitive voltage-gated sodium channels (TTX-S Nav) in rat dorsal root ganglion (DRG) neurons in a concentration- and voltage-dependent manner. Lowers the activation threshold an
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d produces negative shifting of TTX-S sodium current activation curve. Induces shifting of the steady-state inactivation curve to the left, delays the recovery of TTX-S I(Na) from inactivation.
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Toxin BmKT

 Toxin BmKT ELISA Kit
 Toxin BmKT Recombinant
 Toxin BmKT Antibody
Also known as Toxin BmKT (BmK T) (Antitumor-analgesic peptide) (AGAP) (AGSP).
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal trans
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mission (). Tested on mice, has antitumor effect and strong inhibitory effect on pain.
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Toxin BmTxKS4

 Toxin BmTxKS4 ELISA Kit
 Toxin BmTxKS4 Recombinant
 Toxin BmTxKS4 Antibody
Also known as Toxin BmTxKS4 (KS3 toxin).
Reversibly inhibits potassium channels.
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Toxin Boma6a

 Toxin Boma6a ELISA Kit
 Toxin Boma6a Recombinant
 Toxin Boma6a Antibody
Also known as Toxin Boma6a (Alpha-neurotoxin Bom alpha-6a).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
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neuronal transmission.
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Toxin Boma6b

 Toxin Boma6b ELISA Kit
 Toxin Boma6b Recombinant
 Toxin Boma6b Antibody
Also known as Toxin Boma6b (Alpha-neurotoxin Bom alpha-6b).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
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neuronal transmission.
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Toxin Boma6c

 Toxin Boma6c ELISA Kit
 Toxin Boma6c Recombinant
 Toxin Boma6c Antibody
Also known as Toxin Boma6c (Alpha-neurotoxin Bom alpha-6c).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
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neuronal transmission.
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Toxin Boma6d

 Toxin Boma6d ELISA Kit
 Toxin Boma6d Recombinant
 Toxin Boma6d Antibody
Also known as Toxin Boma6d (Alpha-neurotoxin Bom alpha-6d).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
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neuronal transmission.
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Toxin Boma6e

 Toxin Boma6e ELISA Kit
 Toxin Boma6e Recombinant
 Toxin Boma6e Antibody
Also known as Toxin Boma6e (Alpha-neurotoxin Bom alpha-6e).
Binds voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
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neuronal transmission.
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Toxin BomPI

 Toxin BomPI ELISA Kit
 Toxin BomPI Recombinant
 Toxin BomPI Antibody
Also known as Toxin BomPI (Neurotoxin PI).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuron
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al transmission.
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Toxin C10S2C2

 Toxin C10S2C2 ELISA Kit
 Toxin C10S2C2 Recombinant
 Toxin C10S2C2 Antibody
This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions.
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Toxin C13S1C1

 Toxin C13S1C1 ELISA Kit
 Toxin C13S1C1 Recombinant
 Toxin C13S1C1 Antibody
Is cytotoxic against human non-small cell lung adenocarcinoma A-549 cells (LC(50)=56 µg/ml), breast adenocarcinoma MDA-MBsy-231 cells (LC(50)=62 µg/ml) and colorectal adenocarcinoma HT-29 cells (LC(
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50)=110 µg/ml). Shows low hemolytic activity against human erythrocytes (LC(50)>600 µg/ml). Is also cytotoxic against human umbilical vein endothelial HUVEC cells (57 µg/ml) indicating no differential activity against cell lines derived from neoplastic tissues.
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Toxin CaTX-A

 Toxin CaTX-A ELISA Kit
 Toxin CaTX-A Recombinant
 Toxin CaTX-A Antibody
Also known as Toxin CaTX-A (Toxin A) (CAT-1).
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal trans
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membrane ion concentration gradients in susceptible cells.
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Toxin CbtA

 Toxin CbtA ELISA Kit
 Toxin CbtA Recombinant
 Toxin CbtA Antibody
Also known as Toxin CbtA (Toxin YeeV).
Toxic component of a toxin-antitoxin (TA) module. Interacts with cytoskeletal proteins FtsZ and MreB; inhibits FtsZ GTP-dependent polymerization and GTPase activity as well as MreB ATP-dependent polymerization ().
 cbtA ELISA Kit
 cbtA Recombinant
 cbtA Antibody
 yeeV ELISA Kit
 yeeV Recombinant
 yeeV Antibody
 c2532 ELISA Kit
 c2532 Recombinant
 c2532 Antibody
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Toxin CcdB

 Toxin CcdB ELISA Kit
 Toxin CcdB Recombinant
 Toxin CcdB Antibody
Also known as Toxin CcdB (Cytotoxic protein CcdB) (LynB) (Protein G) (Protein LetD).
Toxic component of a toxin-antitoxin (TA) module, functioning in plasmid maintainence. Responsible for the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system. Half-life of over 2 hours. Cell killing by CcdB is accompanied by filamentation, defects in chromosome and plasmid segregation, defects in cell division, formation of anucleate cells, decreased DNA synthesis and plasmid loss. Interferes with the activity of DNA gyrase, inducing it to form a covalent
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GyrA-DNA complex that cannot be resolved, thus promoting breakage of plasmid and chromosomal DNA. DNA breakage requires hydrolyzable ATP. Toxicity is inhibited by labile antitoxin CcdA, which blocks the activity of CcdB; CcdA also removes bound CcdB protein from the CcdB-GyrA complex by forming a CcdA-CcdB complex, a process termed rejuvenation. Also acts to inhibit partitioning of the chromosomal DNA. Functions as a transcriptional corepressor for the ccdAB operon, repression also requires CcdA.
 ccdB ELISA Kit
 ccdB Recombinant
 ccdB Antibody
 letB ELISA Kit
 letB Recombinant
 letB Antibody
 letD ELISA Kit
 letD Recombinant
 letD Antibody
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Toxin CdiA

 Toxin CdiA ELISA Kit
 Toxin CdiA Recombinant
 Toxin CdiA Antibody
Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria (about 1000-fold) in a contact-dependent fashion. Inhibitory cells must be in logarithmic (not stationary) phase to inhibit growth of their targets, but prote
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in synthesis is not necessary (PubMed:16109881, PubMed:25174572). The presence of P or S but not type 1 pili protects the target cells against growth inhibition. BamA on the target cells acts as a receptor for CdiA, while target cell AcrB acts downstream of BamA in CDI for this protein (PubMed:16109881). Receptor function is dependent on extracellular loops of BamA (PubMed:23882017). Cells undergoing CDI show a 2- to 5-fold reversible decrease in aerobic respiration, proton motive force and steady-state ATP levels, suggesting this CT module is an ionophore that disrupts the targets inner cell membrane. Growth recovery requires an energy source. Cells expressing this protein in the absence of CdiI initally form filaments some of which contain multiple nucleoids while others are devoid of nucleoids. CDI cells induce the phage shock response, but pspA is not required for recovery from CDI (PubMed:19124575). CDI is neutralized by its cognate immunity protein CdiI, but not by non-cognate CdiI from other bacteria with different CDI systems (PubMed:21085179).
 cdiA ELISA Kit
 cdiA Recombinant
 cdiA Antibody
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Toxin Cex12

 Toxin Cex12 ELISA Kit
 Toxin Cex12 Recombinant
 Toxin Cex12 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cex8

 Toxin Cex8 ELISA Kit
 Toxin Cex8 Recombinant
 Toxin Cex8 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin CfTX-1

 Toxin CfTX-1 ELISA Kit
 Toxin CfTX-1 Recombinant
 Toxin CfTX-1 Antibody
Also known as Toxin CfTX-1 (Toxin 1).
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal transmembrane
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ion concentration gradients in susceptible cells ().
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Toxin CfTX-2

 Toxin CfTX-2 ELISA Kit
 Toxin CfTX-2 Recombinant
 Toxin CfTX-2 Antibody
Also known as Toxin CfTX-2 (Toxin 2).
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal transmembrane
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ion concentration gradients in susceptible cells ().
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Toxin Cg2

 Toxin Cg2 ELISA Kit
 Toxin Cg2 Recombinant
 Toxin Cg2 Antibody
Binds to sodium channels (Nav) and inhibits them.
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Toxin Cll1

 Toxin Cll1 ELISA Kit
 Toxin Cll1 Recombinant
 Toxin Cll1 Antibody
Also known as Toxin Cll1 (Crustacean-specific toxin 1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials
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thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (). This toxin is only active on crustaceans.
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Toxin Cll2b

 Toxin Cll2b ELISA Kit
 Toxin Cll2b Recombinant
 Toxin Cll2b Antibody
Also known as Toxin Cll2b (Cll 2b) (Toxin II.6).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereb
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y affecting sodium channel activation and promoting spontaneous and repetitive firing (). This toxin had also a depressive action on the classical calcium current activated at high membrane potentials. This toxin is active on mammals.
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Toxin Cll3

 Toxin Cll3 ELISA Kit
 Toxin Cll3 Recombinant
 Toxin Cll3 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll4

 Toxin Cll4 ELISA Kit
 Toxin Cll4 Recombinant
 Toxin Cll4 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll5b

 Toxin Cll5b ELISA Kit
 Toxin Cll5b Recombinant
 Toxin Cll5b Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll5c

 Toxin Cll5c ELISA Kit
 Toxin Cll5c Recombinant
 Toxin Cll5c Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll5c*

 Toxin Cll5c* ELISA Kit
 Toxin Cll5c* Recombinant
 Toxin Cll5c* Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll6

 Toxin Cll6 ELISA Kit
 Toxin Cll6 Recombinant
 Toxin Cll6 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll7

 Toxin Cll7 ELISA Kit
 Toxin Cll7 Recombinant
 Toxin Cll7 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll8

 Toxin Cll8 ELISA Kit
 Toxin Cll8 Recombinant
 Toxin Cll8 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin Cll9

 Toxin Cll9 ELISA Kit
 Toxin Cll9 Recombinant
 Toxin Cll9 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing (). Has some action on peripheral ganglia, but not on other sodium channels such as those from cerebellum granular cells in culture. Induces sleep, suggesting a strong antiepileptic action.
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Toxin Cn1

 Toxin Cn1 ELISA Kit
 Toxin Cn1 Recombinant
 Toxin Cn1 Antibody
Also known as Toxin Cn1 (Toxin II.14) (Toxin 1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereb
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y affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Cn11

 Toxin Cn11 ELISA Kit
 Toxin Cn11 Recombinant
 Toxin Cn11 Antibody
First blocker of sodium channels (Nav) found in scorpions. Is lethal to crustaceans (Cambarellus montezumae), less toxic to insects (crickets) and non-toxic to mammals (mice) at the doses assayed.
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Toxin Cn3

 Toxin Cn3 ELISA Kit
 Toxin Cn3 Recombinant
 Toxin Cn3 Antibody
Also known as Toxin Cn3 (Toxin 3) (Toxin II.9.2.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials the
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reby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin CngtIII

 Toxin CngtIII ELISA Kit
 Toxin CngtIII Recombinant
 Toxin CngtIII Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin CngtIV

 Toxin CngtIV ELISA Kit
 Toxin CngtIV Recombinant
 Toxin CngtIV Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing.
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Toxin CptA

 Toxin CptA ELISA Kit
 Toxin CptA Recombinant
 Toxin CptA Antibody
Toxic component of a toxin-antitoxin (TA) module. Overexpression leads to growth arrest after 5 hours, with initial elongation of cells, followed by swelling. The toxic effects are abrogated by coexpression with antitoxin CptB. Interacts with cytoskeletal proteins FtsZ and MreB; inhibits FtsZ GTP-dependent polymerization as well as MreB ATP-dependent polymerization.
 cptA ELISA Kit
 cptA Recombinant
 cptA Antibody
 ygfX ELISA Kit
 ygfX Recombinant
 ygfX Antibody
 b2896 ELISA Kit
 b2896 Recombinant
 b2896 Antibody
 JW2864 ELISA Kit
 JW2864 Recombinant
 JW2864 Antibody
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Toxin CpTx1

 Toxin CpTx1 ELISA Kit
 Toxin CpTx1 Recombinant
 Toxin CpTx1 Antibody
Spider venom toxin that exhibits cytolytic activity by forming an alpha-helix across the membrane. Causes instant paralysis and death in the larvae of the flesh fly (S.carnaria) at doses of 20 µg/g,
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at doses of less than 10 µg/g causes reversible paralysis. Has cytolytic activity against insect Sf9 cells. Causes stable and irreversible depolarization of fly muscle fibers, leading to contracture at higher toxin concentrations. Destabilizes membranes.
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Toxin CqTX-A

 Toxin CqTX-A ELISA Kit
 Toxin CqTX-A Recombinant
 Toxin CqTX-A Antibody
Also known as Toxin CqTX-A (CQT-A) (Toxin A).
Has potent hemolytic activity. Is lethal to crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disrupting normal trans
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membrane ion concentration gradients in susceptible cells.
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Toxin CrTX-A

 Toxin CrTX-A ELISA Kit
 Toxin CrTX-A Recombinant
 Toxin CrTX-A Antibody
Also known as Toxin CrTX-A (CRT-1) (CrTX-B) (Toxin 1).
Has potent hemolytic activity. Is lethal to mice and crayfish. Causes cutaneous inflammation in humans. May act as a pore-forming toxin, disru
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pting normal transmembrane ion concentration gradients in susceptible cells.
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Toxin CsE8

 Toxin CsE8 ELISA Kit
 Toxin CsE8 Recombinant
 Toxin CsE8 Antibody
Also known as Toxin CsE8 (Neurotoxin 8).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affect
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ing sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin CsE9

 Toxin CsE9 ELISA Kit
 Toxin CsE9 Recombinant
 Toxin CsE9 Antibody
Also known as Toxin CsE9 (Neurotoxin 9).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affect
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ing sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin CsEM1

 Toxin CsEM1 ELISA Kit
 Toxin CsEM1 Recombinant
 Toxin CsEM1 Antibody
Also known as Toxin CsEM1 (CsE M1) (CsEIII).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing (). Highly potent.
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Toxin CsEv1

 Toxin CsEv1 ELISA Kit
 Toxin CsEv1 Recombinant
 Toxin CsEv1 Antibody
Also known as Toxin CsEv1 (CsE v1) (Neurotoxin 1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials ther
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eby affecting sodium channel activation and promoting spontaneous and repetitive firing (). Induces immediate paralysis in crickets after injection, with a total paralysis occurring within 15-30 minutes and lasting for 1-2 hours. Is also lethal to vertebrate (chicks) when injected in very high dosages (more than 100 mg/kg).
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Toxin CsEv2

 Toxin CsEv2 ELISA Kit
 Toxin CsEv2 Recombinant
 Toxin CsEv2 Antibody
Also known as Toxin CsEv2 (CsE v2) (Neurotoxin 2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials ther
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eby affecting sodium channel activation and promoting spontaneous and repetitive firing (). Induces immediate paralysis in crickets after injection, with a total paralysis occurring within 15-30 minutes and lasting for 1-2 hours. Is also lethal to vertebrate (chicks) when injected in very high dosages (more that 100 mg/kg).
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Toxin CsEv3

 Toxin CsEv3 ELISA Kit
 Toxin CsEv3 Recombinant
 Toxin CsEv3 Antibody
Also known as Toxin CsEv3 (CsE v3) (Neurotoxin 3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials ther
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eby affecting sodium channel activation and promoting spontaneous and repetitive firing (). Induces immediate paralysis in crickets after injection, with a total paralysis occurring within 15-30 minutes and lasting for 1-2 hours. Is also lethal to vertebrate (chicks) when injected in very high dosages (more that 100 mg/kg).
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Toxin CsEv4

 Toxin CsEv4 ELISA Kit
 Toxin CsEv4 Recombinant
 Toxin CsEv4 Antibody
Also known as Toxin CsEv4 (CsE v4) (Neurotoxin 4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials ther
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eby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Css39.8

 Toxin Css39.8 ELISA Kit
 Toxin Css39.8 Recombinant
 Toxin Css39.8 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
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spontaneous and repetitive firing. This toxin is lethal to crustaceans (freshwater crayfish (Cambarellus montezumae spp.)), it provokes a reversible paralysis to insects (crickets (Achaeta spp.)), but is not toxic to mice. At high concentrations, it does displace the (beta) mammal-specific toxin Cn2 from rat brain synaptosomes.
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Toxin CSTX-10

 Toxin CSTX-10 ELISA Kit
 Toxin CSTX-10 Recombinant
 Toxin CSTX-10 Antibody
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Toxin CSTX-11

 Toxin CSTX-11 ELISA Kit
 Toxin CSTX-11 Recombinant
 Toxin CSTX-11 Antibody
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Toxin CSTX-12

 Toxin CSTX-12 ELISA Kit
 Toxin CSTX-12 Recombinant
 Toxin CSTX-12 Antibody
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Toxin CSTX-14

 Toxin CSTX-14 ELISA Kit
 Toxin CSTX-14 Recombinant
 Toxin CSTX-14 Antibody
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Toxin CSTX-15

 Toxin CSTX-15 ELISA Kit
 Toxin CSTX-15 Recombinant
 Toxin CSTX-15 Antibody
Table BarTOPTable Bar
 

Toxin CSTX-16

 Toxin CSTX-16 ELISA Kit
 Toxin CSTX-16 Recombinant
 Toxin CSTX-16 Antibody
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Toxin CSTX-17

 Toxin CSTX-17 ELISA Kit
 Toxin CSTX-17 Recombinant
 Toxin CSTX-17 Antibody
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Toxin CSTX-18

 Toxin CSTX-18 ELISA Kit
 Toxin CSTX-18 Recombinant
 Toxin CSTX-18 Antibody
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Toxin CSTX-19

 Toxin CSTX-19 ELISA Kit
 Toxin CSTX-19 Recombinant
 Toxin CSTX-19 Antibody
Table BarTOPTable Bar
 

Toxin CSTX-20

 Toxin CSTX-20 ELISA Kit
 Toxin CSTX-20 Recombinant
 Toxin CSTX-20 Antibody
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Toxin CSTX-8

 Toxin CSTX-8 ELISA Kit
 Toxin CSTX-8 Recombinant
 Toxin CSTX-8 Antibody
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Toxin Doc

 Toxin Doc ELISA Kit
 Toxin Doc Recombinant
 Toxin Doc Antibody
Also known as Toxin Doc (Death on curing protein).
Toxic component of a toxin-antitoxin (TA) module. Upon overexpression causes bacteriostasis. Its effect is neutralized by coexpression with cognate antitoxin PhD. May bind the 30S ribosomal subunit. In M.smegmatis 3 TA modules (VapB-VapC, MazE-MazF and Phd-Doc) may be involved in monitoring the nutritional supply and physiological state of the cell, linking catabolic with anabolic reactions.
 doc ELISA Kit
 doc Recombinant
 doc Antibody
 MSMEG_1278 ELISA Kit
 MSMEG_1278 Recombinant
 MSMEG_1278 Antibody
 MSMEI_1240 ELISA Kit
 MSMEI_1240 Recombinant
 MSMEI_1240 Antibody
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Toxin FitB

 Toxin FitB ELISA Kit
 Toxin FitB Recombinant
 Toxin FitB Antibody
Also known as Toxin FitB (Ribonuclease FitB) (RNase FitB) (Trafficking protein B).
Toxic component of a toxin-antitoxin (TA) module. Plays a role in the speed with which bacteria traverse human epithelial cells; disruption of the locus increases the speed of trafficking about 2-4-fold. FitAB binds to its own promoter better than FitA alone. The expected nuclease activity was not observed for the FitAB complex, perhaps because FitA (the antitoxin) prevents metal binding and thus catalysis by FitB.
 fitB ELISA Kit
 fitB Recombinant
 fitB Antibody
 vapC ELISA Kit
 vapC Recombinant
 vapC Antibody
 NGO0907 ELISA Kit
 NGO0907 Recombinant
 NGO0907 Antibody
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Toxin FS-2

 Toxin FS-2 ELISA Kit
 Toxin FS-2 Recombinant
 Toxin FS-2 Antibody
Also known as Toxin FS-2 (FS2).
Specific blocker of the voltage-dependent L-type calcium channel (Cav1/CACNA1) (PubMed:8826098). Inhibits cardiac contractions ().
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Toxin F-VIII

 Toxin F-VIII ELISA Kit
 Toxin F-VIII Recombinant
 Toxin F-VIII Antibody
Also known as Toxin F-VIII (Toxin DaF8) (Toxin TA2).
Is cytotoxic against A549 cells (LC(50)=106 µg/ml).
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Toxin GaTx1

 Toxin GaTx1 ELISA Kit
 Toxin GaTx1 Recombinant
 Toxin GaTx1 Antibody
Chloride channel ligand. Potently and reversibly inhibits CFTR chloride channels when the channels are in the interburst closed state. May also interact with chloride channels (probably ClC-3/CLCN3) a
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nd MMP2 at the surface of glioma cells. This complex may be then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation.
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Toxin GhoT

 Toxin GhoT ELISA Kit
 Toxin GhoT Recombinant
 Toxin GhoT Antibody
Toxic component of a type V toxin-antitoxin (TA) module. Causes membrane damage when induced by MqsR, slowing cell growth and leading to the formation of dormant persister cells; involved with GhoS, its antitoxin, in reducing cell growth during antibacterial stress. Its toxic effects are neutralized by GhoS, which digests ghoT transcripts in a sequence-specific manner.
 ghoT ELISA Kit
 ghoT Recombinant
 ghoT Antibody
 c5136 ELISA Kit
 c5136 Recombinant
 c5136 Antibody
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Toxin HigB-1

 Toxin HigB-1 ELISA Kit
 Toxin HigB-1 Recombinant
 Toxin HigB-1 Antibody
Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA.
 higB-1 ELISA Kit
 higB-1 Recombinant
 higB-1 Antibody
 VC_A0391 ELISA Kit
 VC_A0391 Recombinant
 VC_A0391 Antibody
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Toxin HigB-2

 Toxin HigB-2 ELISA Kit
 Toxin HigB-2 Recombinant
 Toxin HigB-2 Antibody
Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA.
 higB-2 ELISA Kit
 higB-2 Recombinant
 higB-2 Antibody
 VC_A0468 ELISA Kit
 VC_A0468 Recombinant
 VC_A0468 Antibody
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Toxin HokB

 Toxin HokB ELISA Kit
 Toxin HokB Recombinant
 Toxin HokB Antibody
Toxic component of a type I toxin-antitoxin (TA) module. Its toxic effects are probably neutralized by sRNA antitoxin sokB, which is encoded in trans on the opposite DNA strand (Probable). Expression leads to membrane depolarization; when protein levels are high enough depolarization probably leads to lowered metabolic activity which in turn induces some cells to enter the persistent state in which they transiently survive antibiotic exposure.
 hokB ELISA Kit
 hokB Recombinant
 hokB Antibody
 ydcB ELISA Kit
 ydcB Recombinant
 ydcB Antibody
 b4428 ELISA Kit
 b4428 Recombinant
 b4428 Antibody
 JW5225 ELISA Kit
 JW5225 Recombinant
 JW5225 Antibody
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Toxin ICK-10

 Toxin ICK-10 ELISA Kit
 Toxin ICK-10 Recombinant
 Toxin ICK-10 Antibody
Ion channel inhibitor.
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Toxin ICK-11

 Toxin ICK-11 ELISA Kit
 Toxin ICK-11 Recombinant
 Toxin ICK-11 Antibody
Ion channel inhibitor.
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Toxin ICK-12

 Toxin ICK-12 ELISA Kit
 Toxin ICK-12 Recombinant
 Toxin ICK-12 Antibody
Ion channel inhibitor.
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Toxin ICK-13

 Toxin ICK-13 ELISA Kit
 Toxin ICK-13 Recombinant
 Toxin ICK-13 Antibody
Ion channel inhibitor.
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Toxin ICK-14

 Toxin ICK-14 ELISA Kit
 Toxin ICK-14 Recombinant
 Toxin ICK-14 Antibody
Ion channel inhibitor.
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Toxin ICK-15

 Toxin ICK-15 ELISA Kit
 Toxin ICK-15 Recombinant
 Toxin ICK-15 Antibody
Ion channel inhibitor.
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Toxin ICK-16

 Toxin ICK-16 ELISA Kit
 Toxin ICK-16 Recombinant
 Toxin ICK-16 Antibody
Ion channel inhibitor.
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Toxin ICK-17

 Toxin ICK-17 ELISA Kit
 Toxin ICK-17 Recombinant
 Toxin ICK-17 Antibody
Ion channel inhibitor.
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Toxin ICK-18

 Toxin ICK-18 ELISA Kit
 Toxin ICK-18 Recombinant
 Toxin ICK-18 Antibody
Ion channel inhibitor.
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Toxin ICK-19

 Toxin ICK-19 ELISA Kit
 Toxin ICK-19 Recombinant
 Toxin ICK-19 Antibody
Ion channel inhibitor.
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Toxin ICK-20

 Toxin ICK-20 ELISA Kit
 Toxin ICK-20 Recombinant
 Toxin ICK-20 Antibody
Ion channel inhibitor.
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Toxin ICK-21

 Toxin ICK-21 ELISA Kit
 Toxin ICK-21 Recombinant
 Toxin ICK-21 Antibody
Ion channel inhibitor.
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Toxin ICK-22

 Toxin ICK-22 ELISA Kit
 Toxin ICK-22 Recombinant
 Toxin ICK-22 Antibody
Ion channel inhibitor.
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Toxin ICK-23

 Toxin ICK-23 ELISA Kit
 Toxin ICK-23 Recombinant
 Toxin ICK-23 Antibody
Ion channel inhibitor.
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Toxin ICK-24

 Toxin ICK-24 ELISA Kit
 Toxin ICK-24 Recombinant
 Toxin ICK-24 Antibody
Ion channel inhibitor.
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Toxin ICK-41

 Toxin ICK-41 ELISA Kit
 Toxin ICK-41 Recombinant
 Toxin ICK-41 Antibody
Ion channel inhibitor.
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Toxin ICK-42

 Toxin ICK-42 ELISA Kit
 Toxin ICK-42 Recombinant
 Toxin ICK-42 Antibody
Ion channel inhibitor.
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Toxin ICK-8

 Toxin ICK-8 ELISA Kit
 Toxin ICK-8 Recombinant
 Toxin ICK-8 Antibody
Ion channel inhibitor.
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Toxin ICK-9

 Toxin ICK-9 ELISA Kit
 Toxin ICK-9 Recombinant
 Toxin ICK-9 Antibody
Ion channel inhibitor.
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Toxin II.9

 Toxin II.9 ELISA Kit
 Toxin II.9 Recombinant
 Toxin II.9 Antibody
Binds to sodium channels (Nav) and shift the voltage of activation toward more negative potentials (). This toxin is active on crustaceans.
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Toxin Iob1

 Toxin Iob1 ELISA Kit
 Toxin Iob1 Recombinant
 Toxin Iob1 Antibody
Binds reversibly and blocks N-type voltage-gated calcium channels (Cav).
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Toxin Isom2

 Toxin Isom2 ELISA Kit
 Toxin Isom2 Recombinant
 Toxin Isom2 Antibody
Also known as Toxin Isom2 (IsomTx2).
Excitatory insect beta-toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation
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toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ().
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Toxin KTx8

 Toxin KTx8 ELISA Kit
 Toxin KTx8 Recombinant
 Toxin KTx8 Antibody
Also known as Toxin KTx8 (LmKTx8).
This recombinant toxin inhibits the mammalian voltage-gated potassium channels Kv1.3/KCNA3 in vitro with an IC50 of 26.40 nM.
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Toxin Lc a

 Toxin Lc a ELISA Kit
 Toxin Lc a Recombinant
 Toxin Lc a Antibody
Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), whereas it binds with a low affinity to neuronal alpha-7/CHRNA7 nAChRs.
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Toxin Lc b

 Toxin Lc b ELISA Kit
 Toxin Lc b Recombinant
 Toxin Lc b Antibody
Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), whereas it binds with a low affinity to neuronal alpha-7/CHRNA7 nAChRs.
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Toxin Lqh4

 Toxin Lqh4 ELISA Kit
 Toxin Lqh4 Recombinant
 Toxin Lqh4 Antibody
Also known as Toxin Lqh4 (Lqh IV) (LqhIV) (Toxin IV).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby bloc
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king neuronal transmission (). Intracerebroventricular injection into mice induces immediate convulsions and urination followed by death. Is toxic to insects and mice.
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Toxin LyeTx 1

 Toxin LyeTx 1 ELISA Kit
 Toxin LyeTx 1 Recombinant
 Toxin LyeTx 1 Antibody
Has antimicrobial activity against Gram-positive bacterium S.aureus (MIC=3.79 µM), Gram-negative bacterium E.coli (MIC=7.81 µM) and yeasts C.krusei (MIC=26.3 µM) and C.neoformans (MIC=13.2 µM). Ha
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s hemolytic activity against rabbit erythrocytes. Forms pores in lipid bilayers in vitro; pore formation is reduced when cholesterol is present in the bilayers.
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Toxin MIT1

 Toxin MIT1 ELISA Kit
 Toxin MIT1 Recombinant
 Toxin MIT1 Antibody
Also known as Toxin MIT1 (MIT 1) (Black mamba intestinal toxin 1) (Black mamba venom protein A).
Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2 (PubMed:12054613). Potently contracts gastrointe
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stinal (GI) smooth muscle (PubMed:10567694).
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Toxin MT0934

 Toxin MT0934 ELISA Kit
 Toxin MT0934 Recombinant
 Toxin MT0934 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin MT0933 ().
 MT0934 ELISA Kit
 MT0934 Recombinant
 MT0934 Antibody
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Toxin MT2730

 Toxin MT2730 ELISA Kit
 Toxin MT2730 Recombinant
 Toxin MT2730 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin MT2731 ().
 MT2730 ELISA Kit
 MT2730 Recombinant
 MT2730 Antibody
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Toxin OAIP 5

 Toxin OAIP 5 ELISA Kit
 Toxin OAIP 5 Recombinant
 Toxin OAIP 5 Antibody
Probable ion channel inhibitor. Shows insecticidal activity when injected into mealworms.
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Toxin OcyKTx3

 Toxin OcyKTx3 ELISA Kit
 Toxin OcyKTx3 Recombinant
 Toxin OcyKTx3 Antibody
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Toxin Os1

 Toxin Os1 ELISA Kit
 Toxin Os1 Recombinant
 Toxin Os1 Antibody
Also known as Toxin Os1 (Os-1).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmis
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sion (). This toxin possesses a high paralytic activity against mice.
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Toxin ParE

 Toxin ParE ELISA Kit
 Toxin ParE Recombinant
 Toxin ParE Antibody
Also known as Toxin ParE (Gyrase inhibitor ParE).
Toxin component of a toxin-antitoxin (TA) module involved in plasmid partition. Acts by inhibiting DNA gyrase, converting supercoiled plasmid DNA into a singly cleaved linear form in an ATP-dependent fashion. To do so it probably interacts with one of the gyrase subunits. Gyrase inhibition is prevented by antitoxin ParD, and is reversed in vitro
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by incubation with ParD. In cells that have lost the plasmid filamentation and growth inhibition occur; this is suppressed when ParD is supplied in trans. The parDE operon alone is capable of stabilizing an RK2-derived minireplicon under defined growth conditions in several different Gram-negative bacteria. It does so by the post-segregational killing (PSK) of plasmid-free cells, also referred to as a plasmid addiction system.
 parE ELISA Kit
 parE Recombinant
 parE Antibody
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Toxin ParE1

 Toxin ParE1 ELISA Kit
 Toxin ParE1 Recombinant
 Toxin ParE1 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD1 but no other ParD or RelB antitoxin. Low levels of wild-type toxin in the absence of antitoxin decreases the rate of cell growth, and results in death or loss of colony formation abilities and greatly elongated cells. Low levels of a mutant missing the last 4 residues lead
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s to loss of cell division while cell elongation continues.
 parE1 ELISA Kit
 parE1 Recombinant
 parE1 Antibody
 CC_0873 ELISA Kit
 CC_0873 Recombinant
 CC_0873 Antibody
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Toxin ParE2

 Toxin ParE2 ELISA Kit
 Toxin ParE2 Recombinant
 Toxin ParE2 Antibody
Toxic component of a toxin-antitoxin (TA) module. Upon expression in E.coli inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD2.
 parE2 ELISA Kit
 parE2 Recombinant
 parE2 Antibody
 Rv2142c ELISA Kit
 Rv2142c Recombinant
 Rv2142c Antibody
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Toxin ParE3

 Toxin ParE3 ELISA Kit
 Toxin ParE3 Recombinant
 Toxin ParE3 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD3 but no other ParD or RelB antitoxin.
 parE3 ELISA Kit
 parE3 Recombinant
 parE3 Antibody
 CC_2756 ELISA Kit
 CC_2756 Recombinant
 CC_2756 Antibody
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Toxin ParE4

 Toxin ParE4 ELISA Kit
 Toxin ParE4 Recombinant
 Toxin ParE4 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin ParD4 but no other ParD or RelB antitoxin.
 parE4 ELISA Kit
 parE4 Recombinant
 parE4 Antibody
 CC_2984 ELISA Kit
 CC_2984 Recombinant
 CC_2984 Antibody
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Toxin PAU_02230

 Toxin PAU_02230 ELISA Kit
 Toxin PAU_02230 Recombinant
 Toxin PAU_02230 Antibody
Also known as Toxin PAU_02230 (Photorhabdus asymbiotica toxin) (PaTox).
Toxin that acts on host cells by modifying Rho proteins by tyrosine GlcNAcylation and heterotrimeric G alpha proteins by deamidation. Catalyzes the mono-O-GlcNAcylation of small GTPases of the Rho family (RhoA, RhoB, RhoC, Rac1, Rac2, Rac3, Cdc42) in eukaryotic host cells at the conserved tyrosine residue located in the swi
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tch I region (Tyr-32/34), using UDP-N-acetylglucosamine (UDP-GlcNAc) as the sugar donor; other GTPases of the Rho, Ras or Rab families are not substrates. Tyrosine glycosylation inhibits Rho activation and prevents interaction with downstream effectors, resulting in actin disassembly, inhibition of phagocytosis, cell rounding, and toxicity toward insects and mammalian cells. Also catalyzes the deamidation of the catalytic glutamine in heterotrimeric G alpha proteins (Gi, Gq/11), which blocks GTP hydrolysis and arrests the G proteins in a permanent active state leading to activation of Rho GTPases. Thus, PaTox hijacks host GTPase signaling in a bidirectional manner by deamidation-induced activation and glycosylation-induced inactivation of GTPases.
 PAU_02230 ELISA Kit
 PAU_02230 Recombinant
 PAU_02230 Antibody
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Toxin PBITx1

 Toxin PBITx1 ELISA Kit
 Toxin PBITx1 Recombinant
 Toxin PBITx1 Antibody
Also known as Toxin PBITx1 (sITx10).
Toxin with unknown function in healthy organisms. On glioma cells, interacts with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cel
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ls. This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation ().
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Toxin PezT

 Toxin PezT ELISA Kit
 Toxin PezT Recombinant
 Toxin PezT Antibody
Also known as Toxin PezT (UDP-N-acetylglucosamine kinase) (UNAG kinase) (Zeta toxin).
Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Upon expression in E.coli results in
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decreased cell growth and viability, followed 3 hours later by growth restoration; the toxic effect and phosphorylation of UNAG are neutralized by coexpression with cognate antitoxin PezA. A mutant lacking the last 11 residues is stably maintained in E.coli, unlike the wild-type which undergoes spontaneous mutation. Expression of the deletion mutant in rapidly growing liquid cultures leads to cell bulging, permeabilization and massive lysis by 1 hour. Cells that survive are not able to undergo cytokinesis. Expression in slowly growing cells leads to bulging but not lysis.
 pezT ELISA Kit
 pezT Recombinant
 pezT Antibody
 SP_1051 ELISA Kit
 SP_1051 Recombinant
 SP_1051 Antibody
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Toxin Pg8

 Toxin Pg8 ELISA Kit
 Toxin Pg8 Recombinant
 Toxin Pg8 Antibody
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
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Toxin PgKL2

 Toxin PgKL2 ELISA Kit
 Toxin PgKL2 Recombinant
 Toxin PgKL2 Antibody
Also known as Toxin PgKL2 (Kurtoxin-like 2) (Kurtoxin-like II) (KLII).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated chann
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els, thereby blocking neuronal transmission. This toxin inhibits cardiac sodium channels and voltage-gated T-type calcium channels (Cav3.3/CACNA1I) ().
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Toxin Plt

 Toxin Plt ELISA Kit
 Toxin Plt Recombinant
 Toxin Plt Antibody
Shows moderate insect toxicity coupled with mild effect on mice.
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Toxin Ptu1

 Toxin Ptu1 ELISA Kit
 Toxin Ptu1 Recombinant
 Toxin Ptu1 Antibody
Binds reversibly and blocks N-type voltage-gated calcium channels (Cav).
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Toxin RelE

 Toxin RelE ELISA Kit
 Toxin RelE Recombinant
 Toxin RelE Antibody
Also known as Toxin RelE (Putative endoribonuclease RelE).
Toxic component of a toxin-antitoxin (TA) module. Has RNase activity (). Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB (shown only for M.smegmatis).
 relE ELISA Kit
 relE Recombinant
 relE Antibody
 relE1 ELISA Kit
 relE1 Recombinant
 relE1 Antibody
 Rv1246c ELISA Kit
 Rv1246c Recombinant
 Rv1246c Antibody
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Toxin RelE1

 Toxin RelE1 ELISA Kit
 Toxin RelE1 Recombinant
 Toxin RelE1 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB1 but no other ParD or RelB antitoxin.
 relE1 ELISA Kit
 relE1 Recombinant
 relE1 Antibody
 CC_0802 ELISA Kit
 CC_0802 Recombinant
 CC_0802 Antibody
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Toxin RelE2

 Toxin RelE2 ELISA Kit
 Toxin RelE2 Recombinant
 Toxin RelE2 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB2 but no other ParD or RelB antitoxin.
 relE2 ELISA Kit
 relE2 Recombinant
 relE2 Antibody
 CC_2513 ELISA Kit
 CC_2513 Recombinant
 CC_2513 Antibody
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Toxin RelE3

 Toxin RelE3 ELISA Kit
 Toxin RelE3 Recombinant
 Toxin RelE3 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB3 but no other ParD or RelB antitoxin.
 relE3 ELISA Kit
 relE3 Recombinant
 relE3 Antibody
 CC_2880 ELISA Kit
 CC_2880 Recombinant
 CC_2880 Antibody
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Toxin RelE4

 Toxin RelE4 ELISA Kit
 Toxin RelE4 Recombinant
 Toxin RelE4 Antibody
Toxic component of a toxin-antitoxin (TA) module. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB4 but no other ParD or RelB antitoxin.
 relE4 ELISA Kit
 relE4 Recombinant
 relE4 Antibody
 CC_3131 ELISA Kit
 CC_3131 Recombinant
 CC_3131 Antibody
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Toxin RelG

 Toxin RelG ELISA Kit
 Toxin RelG Recombinant
 Toxin RelG Antibody
Also known as Toxin RelG (Putative endoribonuclease RelG).
Toxic component of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides (). Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with cognate antitoxin RelB2 (shown only for M.smegmatis). Overexpression also increases the number of gentamicin-tolerant and levofloxacin-tolerant persister cells.
 relG ELISA Kit
 relG Recombinant
 relG Antibody
 relE2 ELISA Kit
 relE2 Recombinant
 relE2 Antibody
 Rv2866 ELISA Kit
 Rv2866 Recombinant
 Rv2866 Antibody
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Toxin RelK

 Toxin RelK ELISA Kit
 Toxin RelK Recombinant
 Toxin RelK Antibody
Also known as Toxin RelK (Endoribonuclease YoeB) (Putative mRNA interferase RelE3) (Putative mRNA interferase YoeB) (Toxin YoeB).
Toxic component of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides (). Overexpression in M.tuberculosis or M.smegmatis inhibits colony formation in a bacteriostatic rather than bacteriocidal fashion. Its toxic effect is neutralized by coexpression with antitoxin RelJ (shown only for M.smegmatis). Overexpression also increases the number of rifampcin-tolerant persister cells.
 relK ELISA Kit
 relK Recombinant
 relK Antibody
 relE3 ELISA Kit
 relE3 Recombinant
 relE3 Antibody
 yoeB ELISA Kit
 yoeB Recombinant
 yoeB Antibody
 Rv3358 ELISA Kit
 Rv3358 Recombinant
 Rv3358 Antibody
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Toxin Rv0299

 Toxin Rv0299 ELISA Kit
 Toxin Rv0299 Recombinant
 Toxin Rv0299 Antibody
Toxic component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312.
 Rv0299 ELISA Kit
 Rv0299 Recombinant
 Rv0299 Antibody
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Toxin Rv0910

 Toxin Rv0910 ELISA Kit
 Toxin Rv0910 Recombinant
 Toxin Rv0910 Antibody
Toxic component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0909. Does not exert its toxic effect via translation.
 Rv0910 ELISA Kit
 Rv0910 Recombinant
 Rv0910 Antibody
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Toxin Rv2653c

 Toxin Rv2653c ELISA Kit
 Toxin Rv2653c Recombinant
 Toxin Rv2653c Antibody
Toxic component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv2654c.
 Rv2653c ELISA Kit
 Rv2653c Recombinant
 Rv2653c Antibody
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Toxin S4C8

 Toxin S4C8 ELISA Kit
 Toxin S4C8 Recombinant
 Toxin S4C8 Antibody
This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions.
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Toxin S5C1

 Toxin S5C1 ELISA Kit
 Toxin S5C1 Recombinant
 Toxin S5C1 Antibody
Inhibits ADP-induced platelet aggregation and inhibits the binding of purified platelet fibrinogen receptor alpha-IIb/beta-3 (ITGA2B/ITGB3) to immobilized fibrinogen.
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Toxin S5C10

 Toxin S5C10 ELISA Kit
 Toxin S5C10 Recombinant
 Toxin S5C10 Antibody
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
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Toxin S5C4

 Toxin S5C4 ELISA Kit
 Toxin S5C4 Recombinant
 Toxin S5C4 Antibody
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Toxin S6C6

 Toxin S6C6 ELISA Kit
 Toxin S6C6 Recombinant
 Toxin S6C6 Antibody
May enhance presynaptic acetylcholine release.
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Toxin Tb1

 Toxin Tb1 ELISA Kit
 Toxin Tb1 Recombinant
 Toxin Tb1 Antibody
Also known as Toxin Tb1 (PT-Mice-beta* NaTx6.2) (Tb-gamma).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potent
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ials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (). Is lethal to mice (PubMed:8611151).
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Toxin Tb2

 Toxin Tb2 ELISA Kit
 Toxin Tb2 Recombinant
 Toxin Tb2 Antibody
Also known as Toxin Tb2 (P-beta* NaTx5.3) (Toxin III-8).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potential
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s thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active on mammals ().
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Toxin Tb2-II

 Toxin Tb2-II ELISA Kit
 Toxin Tb2-II Recombinant
 Toxin Tb2-II Antibody
Also known as Toxin Tb2-II (P-Mice-Ins-beta* NaTx5.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials
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thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (). This toxin is active against both mammals and insects.
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Toxin Tb3

 Toxin Tb3 ELISA Kit
 Toxin Tb3 Recombinant
 Toxin Tb3 Antibody
Also known as Toxin Tb3 (P-Mice-alpha* NaTx3.3) (TbTx IV-5).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, there
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by blocking neuronal transmission (). Is lethal to mice (PubMed:8611151).
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Toxin Tb4

 Toxin Tb4 ELISA Kit
 Toxin Tb4 Recombinant
 Toxin Tb4 Antibody
Also known as Toxin Tb4 (TbTx-VI) (TbTx6).
Not toxic to mice.
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Toxin TbTx5

 Toxin TbTx5 ELISA Kit
 Toxin TbTx5 Recombinant
 Toxin TbTx5 Antibody
Also known as Toxin TbTx5 (T-alpha* NaTx3.4).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neu
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ronal transmission.
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Toxin Tco-gamma

 Toxin Tco-gamma ELISA Kit
 Toxin Tco-gamma Recombinant
 Toxin Tco-gamma Antibody
Also known as Toxin Tco-gamma (T-beta* NaTx6.4) (Toxin gamma-like).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negativ
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e potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td1

 Toxin Td1 ELISA Kit
 Toxin Td1 Recombinant
 Toxin Td1 Antibody
Also known as Toxin Td1 (PT-beta* NaTx13.1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td10

 Toxin Td10 ELISA Kit
 Toxin Td10 Recombinant
 Toxin Td10 Antibody
Also known as Toxin Td10 (T-beta* NaTx13.5).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td11

 Toxin Td11 ELISA Kit
 Toxin Td11 Recombinant
 Toxin Td11 Antibody
Also known as Toxin Td11 (T-beta* NaTx13.6).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td12

 Toxin Td12 ELISA Kit
 Toxin Td12 Recombinant
 Toxin Td12 Antibody
Also known as Toxin Td12 (T-beta* NaTx13.7).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing.
Table BarTOPTable Bar
 

Toxin Td2

 Toxin Td2 ELISA Kit
 Toxin Td2 Recombinant
 Toxin Td2 Antibody
Also known as Toxin Td2 (P*T-beta* NaTx13.2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby a
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ffecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td3

 Toxin Td3 ELISA Kit
 Toxin Td3 Recombinant
 Toxin Td3 Antibody
Also known as Toxin Td3 (P*T-beta NaTx13.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
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fecting sodium channel activation and promoting spontaneous and repetitive firing.
Table BarTOPTable Bar
 

Toxin Td4

 Toxin Td4 ELISA Kit
 Toxin Td4 Recombinant
 Toxin Td4 Antibody
Also known as Toxin Td4 (P*T-beta* NaTx14.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby a
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ffecting sodium channel activation and promoting spontaneous and repetitive firing.
Table BarTOPTable Bar
 

Toxin Td5

 Toxin Td5 ELISA Kit
 Toxin Td5 Recombinant
 Toxin Td5 Antibody
Also known as Toxin Td5 (P*T-beta* NaTx14.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby a
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ffecting sodium channel activation and promoting spontaneous and repetitive firing.
Table BarTOPTable Bar
 

Toxin Td6

 Toxin Td6 ELISA Kit
 Toxin Td6 Recombinant
 Toxin Td6 Antibody
Also known as Toxin Td6 (T-beta* NaTx13.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td7

 Toxin Td7 ELISA Kit
 Toxin Td7 Recombinant
 Toxin Td7 Antibody
Also known as Toxin Td7 (T-beta* NaTx14.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td8

 Toxin Td8 ELISA Kit
 Toxin Td8 Recombinant
 Toxin Td8 Antibody
Also known as Toxin Td8 (PT-beta* NaTx14.6).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
>>>
fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Td9

 Toxin Td9 ELISA Kit
 Toxin Td9 Recombinant
 Toxin Td9 Antibody
Also known as Toxin Td9 (T-beta* NaTx14.7).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin TdII-1

 Toxin TdII-1 ELISA Kit
 Toxin TdII-1 Recombinant
 Toxin TdII-1 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
>>>
spontaneous and repetitive firing (). This toxin is active against mammals and crustaceans.
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Toxin TdII-2

 Toxin TdII-2 ELISA Kit
 Toxin TdII-2 Recombinant
 Toxin TdII-2 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
>>>
spontaneous and repetitive firing (). This toxin is active against mammals and crustaceans.
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Toxin TdII-3

 Toxin TdII-3 ELISA Kit
 Toxin TdII-3 Recombinant
 Toxin TdII-3 Antibody
Binds voltage-independently to sodium channels (Nav) and shifts the voltage of activation toward more negative potentials (). This toxin is active against mammals and also affects neuromuscular prepar
>>>
ations of frog.
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Toxin TdII-4

 Toxin TdII-4 ELISA Kit
 Toxin TdII-4 Recombinant
 Toxin TdII-4 Antibody
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting
>>>
spontaneous and repetitive firing (). This toxin is active against mammals and also affects neuromuscular preparations of frog.
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Toxin TdNa1

 Toxin TdNa1 ELISA Kit
 Toxin TdNa1 Recombinant
 Toxin TdNa1 Antibody
Also known as Toxin TdNa1 (PT-Arthr*-beta* NaTx2.2).
Inhibits the sodium (Nav) currents in an apparent irreversible manner. Produces small depolarization and induces repetitive firing in squid axon
>>>
s. Is specific for arthropods (crickets, triatomides, crabs and squids), but is non-toxic to mice ().
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Toxin TdNa10

 Toxin TdNa10 ELISA Kit
 Toxin TdNa10 Recombinant
 Toxin TdNa10 Antibody
Also known as Toxin TdNa10 (T-alpha* NaTx7.2).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking ne
>>>
uronal transmission. This toxin binds, in vitro, to sodium channels and inhibits the inactivation of the activated channels. Seems not toxic to mice, crickets and sweet-water shrimps ().
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Toxin TdNa2

 Toxin TdNa2 ELISA Kit
 Toxin TdNa2 Recombinant
 Toxin TdNa2 Antibody
Also known as Toxin TdNa2 (T-Arthr*-beta* NaTx2.3).
Inhibits the sodium currents (Nav) in an apparent irreversible manner. Produces small depolarization and induces repetitive firing in squid axons
>>>
. Is specific for arthropods (crickets, triatomides, crabs and squids), but is non-toxic to mice ().
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Toxin TdNa3

 Toxin TdNa3 ELISA Kit
 Toxin TdNa3 Recombinant
 Toxin TdNa3 Antibody
Also known as Toxin TdNa3 (PT-Arthr*-beta* NaTx2.4).
Inhibits the sodium currents (Nav) in an apparent irreversible manner. Produces small depolarization and induces repetitive firing in squid axon
>>>
s. Is specific for arthropods (crickets, triatomides, crabs and squids), but is non-toxic to mice ().
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Toxin TdNa5

 Toxin TdNa5 ELISA Kit
 Toxin TdNa5 Recombinant
 Toxin TdNa5 Antibody
Also known as Toxin TdNa5 (T-Arthr*-beta* NaTx2.5).
Inhibits the sodium currents (Nav) in an apparent irreversible manner. Produces small depolarization and induces repetitive firing in squid axons
>>>
. Is specific for arthropods (crickets, triatomides, crabs and squids), but is non-toxic to mice ().
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Toxin TdNa6

 Toxin TdNa6 ELISA Kit
 Toxin TdNa6 Recombinant
 Toxin TdNa6 Antibody
Also known as Toxin TdNa6 (PT-Arthr*-beta* NaTx1.2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials th
>>>
ereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Is toxic to arthropods ().
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Toxin TdNa7

 Toxin TdNa7 ELISA Kit
 Toxin TdNa7 Recombinant
 Toxin TdNa7 Antibody
Also known as Toxin TdNa7 (PT-beta* NaTx13.8).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby
>>>
affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin TdNa8

 Toxin TdNa8 ELISA Kit
 Toxin TdNa8 Recombinant
 Toxin TdNa8 Antibody
Also known as Toxin TdNa8 (P*T-alpha* NaTx3.6).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking n
>>>
euronal transmission.
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Toxin TdNa9

 Toxin TdNa9 ELISA Kit
 Toxin TdNa9 Recombinant
 Toxin TdNa9 Antibody
Also known as Toxin TdNa9 (PT-alpha* NaTx7.1).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking ne
>>>
uronal transmission. This toxin binds, in vitro, to sodium channels and inhibits the inactivation of the activated channels. Seems not toxic to mice, crickets and sweet-water shrimps ().
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Toxin To1

 Toxin To1 ELISA Kit
 Toxin To1 Recombinant
 Toxin To1 Antibody
Also known as Toxin To1 (PT-not alpha NaTx12.1) (Toxin Tc49b) (Toxin To49b).
Affects the sodium (Nav) current permeability of rat cerebellum granular cells. This effect is partially reversible. Doe
>>>
s not modify the function of the Shaker B potassium channels.
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Toxin To10

 Toxin To10 ELISA Kit
 Toxin To10 Recombinant
 Toxin To10 Antibody
Also known as Toxin To10 (T-alpha* NaTx3.9).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neur
>>>
onal transmission.
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Toxin To11

 Toxin To11 ELISA Kit
 Toxin To11 Recombinant
 Toxin To11 Antibody
Also known as Toxin To11 (T NaTx14.9).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affectin
>>>
g sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To12

 Toxin To12 ELISA Kit
 Toxin To12 Recombinant
 Toxin To12 Antibody
Also known as Toxin To12 (T-beta* NaTx5.5).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To13

 Toxin To13 ELISA Kit
 Toxin To13 Recombinant
 Toxin To13 Antibody
Also known as Toxin To13 (T NaTx8.1).
Inhibits voltage-gated sodium channels (Nav).
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Toxin To14

 Toxin To14 ELISA Kit
 Toxin To14 Recombinant
 Toxin To14 Antibody
Also known as Toxin To14 (T-alpha* NaTx3.10).
Inhibits voltage-gated sodium channels (Nav).
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Toxin To15

 Toxin To15 ELISA Kit
 Toxin To15 Recombinant
 Toxin To15 Antibody
Also known as Toxin To15 (T-beta* NaTx1.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To27

 Toxin To27 ELISA Kit
 Toxin To27 Recombinant
 Toxin To27 Antibody
Also known as Toxin To27 (Toxin Tc27).
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Toxin To29

 Toxin To29 ELISA Kit
 Toxin To29 Recombinant
 Toxin To29 Antibody
Also known as Toxin To29 (Toxin Tc29).
Table BarTOPTable Bar
 

Toxin To3

 Toxin To3 ELISA Kit
 Toxin To3 Recombinant
 Toxin To3 Antibody
Also known as Toxin To3 (PT-alpha' NaTx14.2) (Toxin Tc48b/Tc49a) (Toxin To48b/To49a).
Affects sodium-permeability in pituitary GH3 cells in culture. Inhibits the inactivation of sodium activated ch
>>>
annels (Nav). Slightly delays the activation time course, and consequently the time to peak. Shifts the voltage dependence of the activation to more negative potentials. Does not reduce the peak sodium-current amplitude.
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Toxin To31

 Toxin To31 ELISA Kit
 Toxin To31 Recombinant
 Toxin To31 Antibody
Also known as Toxin To31 (Toxin Tc31).
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Toxin To33

 Toxin To33 ELISA Kit
 Toxin To33 Recombinant
 Toxin To33 Antibody
Also known as Toxin To33 (Toxin Tc33).
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Toxin To35

 Toxin To35 ELISA Kit
 Toxin To35 Recombinant
 Toxin To35 Antibody
Also known as Toxin To35 (Toxin Tc35).
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Toxin To37

 Toxin To37 ELISA Kit
 Toxin To37 Recombinant
 Toxin To37 Antibody
Also known as Toxin To37 (Toxin Tc37).
Table BarTOPTable Bar
 

Toxin To39

 Toxin To39 ELISA Kit
 Toxin To39 Recombinant
 Toxin To39 Antibody
Also known as Toxin To39 (Toxin Tc39).
Table BarTOPTable Bar
 

Toxin To4

 Toxin To4 ELISA Kit
 Toxin To4 Recombinant
 Toxin To4 Antibody
Also known as Toxin To4 (PT-beta* NaTx13.9) (Toxin Tc54) (Toxin To54).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more nega
>>>
tive potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To40

 Toxin To40 ELISA Kit
 Toxin To40 Recombinant
 Toxin To40 Antibody
Also known as Toxin To40 (Toxin Tc40).
Table BarTOPTable Bar
 

Toxin To41

 Toxin To41 ELISA Kit
 Toxin To41 Recombinant
 Toxin To41 Antibody
Also known as Toxin To41 (Toxin Tc41).
Table BarTOPTable Bar
 

Toxin To46

 Toxin To46 ELISA Kit
 Toxin To46 Recombinant
 Toxin To46 Antibody
Also known as Toxin To46 (Toxin Tc46).
Table BarTOPTable Bar
 

Toxin To5

 Toxin To5 ELISA Kit
 Toxin To5 Recombinant
 Toxin To5 Antibody
Also known as Toxin To5 (PT-Arthr*-beta* NaTx2.7) (Toxin Tc66) (Toxin To66).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward mor
>>>
e negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To56

 Toxin To56 ELISA Kit
 Toxin To56 Recombinant
 Toxin To56 Antibody
Also known as Toxin To56 (Toxin Tc56).
Table BarTOPTable Bar
 

Toxin To58

 Toxin To58 ELISA Kit
 Toxin To58 Recombinant
 Toxin To58 Antibody
Also known as Toxin To58 (Toxin Tc58).
Table BarTOPTable Bar
 

Toxin To6

 Toxin To6 ELISA Kit
 Toxin To6 Recombinant
 Toxin To6 Antibody
Also known as Toxin To6 (PT-alpha* NaTx7.5) (Toxin Tc43) (Toxin To43).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more nega
>>>
tive potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To61

 Toxin To61 ELISA Kit
 Toxin To61 Recombinant
 Toxin To61 Antibody
Also known as Toxin To61 (Toxin Tc61).
Table BarTOPTable Bar
 

Toxin To64

 Toxin To64 ELISA Kit
 Toxin To64 Recombinant
 Toxin To64 Antibody
Also known as Toxin To64 (Toxin Tc64).
Table BarTOPTable Bar
 

Toxin To7

 Toxin To7 ELISA Kit
 Toxin To7 Recombinant
 Toxin To7 Antibody
Also known as Toxin To7 (PT-alpha* NaTx7.6) (Toxin Tc50) (Toxin To50).
Inhibits voltage-gated sodium channels (Nav).
Table BarTOPTable Bar
 

Toxin To8

 Toxin To8 ELISA Kit
 Toxin To8 Recombinant
 Toxin To8 Antibody
Also known as Toxin To8 (PT-beta* NaTx10.1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
>>>
fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin To83

 Toxin To83 ELISA Kit
 Toxin To83 Recombinant
 Toxin To83 Antibody
Also known as Toxin To83 (Toxin Tc83).
Table BarTOPTable Bar
 

Toxin To9

 Toxin To9 ELISA Kit
 Toxin To9 Recombinant
 Toxin To9 Antibody
Also known as Toxin To9 (T-alpha* NaTx3.8).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuro
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nal transmission.
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Toxin tox21A

 Toxin tox21A ELISA Kit
 Toxin tox21A Recombinant
 Toxin tox21A Antibody
Also known as Toxin tox21A (Insect-selective neurotoxin TxP-I homolog).
Has contracting-paralyzing activity in insect larvae.
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Toxin Tpa3

 Toxin Tpa3 ELISA Kit
 Toxin Tpa3 Recombinant
 Toxin Tpa3 Antibody
Unknown. Is not toxic to mammals.
Table BarTOPTable Bar
 

Toxin Tpa4

 Toxin Tpa4 ELISA Kit
 Toxin Tpa4 Recombinant
 Toxin Tpa4 Antibody
Also known as Toxin Tpa4 (T-alpha* NaTx3.7).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neur
>>>
onal transmission.
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Toxin Tpa5

 Toxin Tpa5 ELISA Kit
 Toxin Tpa5 Recombinant
 Toxin Tpa5 Antibody
Also known as Toxin Tpa5 (T-alpha* NaTx7.2).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
>>>
fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Tpa6

 Toxin Tpa6 ELISA Kit
 Toxin Tpa6 Recombinant
 Toxin Tpa6 Antibody
Also known as Toxin Tpa6 (T-alpha* NaTx7.4).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
>>>
fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Tpa7

 Toxin Tpa7 ELISA Kit
 Toxin Tpa7 Recombinant
 Toxin Tpa7 Antibody
Also known as Toxin Tpa7 (T-beta* NaTx1.3).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby aff
>>>
ecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Tpa8

 Toxin Tpa8 ELISA Kit
 Toxin Tpa8 Recombinant
 Toxin Tpa8 Antibody
Also known as Toxin Tpa8 (T NaTx9.1).
Excitatory insect beta-toxins induce a spastic paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activatio
>>>
n toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing ().
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Toxin Ts16

 Toxin Ts16 ELISA Kit
 Toxin Ts16 Recombinant
 Toxin Ts16 Antibody
Also known as Toxin Ts16 (Tityustoxin-16).
Blocks potassium channels.
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Toxin Ts4

 Toxin Ts4 ELISA Kit
 Toxin Ts4 Recombinant
 Toxin Ts4 Antibody
Also known as Toxin Ts4 (Non-toxic protein TsNTxP) (NTxP) (P-Allerg-alpha* NaTx4.1) (PT-Immun-alpha* NaTx4.2) (Tityustoxin VI) (Ts VI) (TsTX-VI) (TsTXVI) (TsVI) (Tityustoxin-6) (Ts-6).
Not toxic. I
>>>
nduces an immune response similar to that induced by whole venom. Induces a dose dependent release of the neurotransmitters glutamic acid and gamma aminobutyric acid from rat brain synaptosomes. Thus, polyclonal antibodies raised against this protein can neutralize the effects of the venom.
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Toxin Tst1

 Toxin Tst1 ELISA Kit
 Toxin Tst1 Recombinant
 Toxin Tst1 Antibody
Also known as Toxin Tst1 (PT-Mice-beta* NaTx6.3) (Tst-gamma).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative pote
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ntials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals (). Is toxic to mice (PubMed:8611151).
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Toxin Tst2

 Toxin Tst2 ELISA Kit
 Toxin Tst2 Recombinant
 Toxin Tst2 Antibody
Also known as Toxin Tst2 (P-Mice-beta* NaTx5.2) (Tityustoxin II) (TsTX-II) (Toxin III-8).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of
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the activated channels, thereby blocking neuronal transmission (). Is toxic to mice (PubMed:8611151).
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Toxin Tst3

 Toxin Tst3 ELISA Kit
 Toxin Tst3 Recombinant
 Toxin Tst3 Antibody
Also known as Toxin Tst3 (P-alpha* NaTx3.5).
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neur
>>>
onal transmission.
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Toxin Tx1

 Toxin Tx1 ELISA Kit
 Toxin Tx1 Recombinant
 Toxin Tx1 Antibody
Also known as Toxin Tx1 (PpTx1).
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Toxin Tx7335

 Toxin Tx7335 ELISA Kit
 Toxin Tx7335 Recombinant
 Toxin Tx7335 Antibody
Activates bacterial pH-gated potassium channel KcsA by binding to its extracellular domain, probably at a site different from channel inhibitors. Increases both mean open time and open probability of
>>>
KscA.
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Toxin TxP-I

 Toxin TxP-I ELISA Kit
 Toxin TxP-I Recombinant
 Toxin TxP-I Antibody
Also known as Toxin TxP-I (Tox34).
Part of a complex mixture of neurotoxins which P.tritici utilizes to capture prey. It has contracting-paralyzing activity in insects.
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Toxin Tz2

 Toxin Tz2 ELISA Kit
 Toxin Tz2 Recombinant
 Toxin Tz2 Antibody
Also known as Toxin Tz2 (P*T-beta* NaTx1.1).
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby af
>>>
fecting sodium channel activation and promoting spontaneous and repetitive firing.
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Toxin Up-1

 Toxin Up-1 ELISA Kit
 Toxin Up-1 Recombinant
 Toxin Up-1 Antibody
Also known as Toxin Up-1 (UpI).
This toxin is a potent hemolysin devoid of enzymatic activity. Its hemolytic activity is inhibited by sphingomyelin but not by cholesterol. In erythrocyte membranes,
>>>
it causes numerous cell membrane ruptures. It also exerces cytotoxicity to different cell lines. It exerces a positive inotropic effect. Also causes hemorrhage and necrosis by dilation of the blood vessels in the skin, and vascular leakage of fluids and rupture of alveolar walls of the lungs. Is a potent ichtyotoxin. May act as a pore-forming toxin.
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Toxin VapC4

 Toxin VapC4 ELISA Kit
 Toxin VapC4 Recombinant
 Toxin VapC4 Antibody
Also known as Toxin VapC4 (Ribonuclease VapC4) (RNase VapC4) (VapC-mt4).
Toxic component of a type II toxin-antitoxin (TA) module. Probably exerts its toxic effect by binding to mRNA, inhibiting translation. Binds to, recognizes and cleaves ssRNA at ACGC and AC(A/U)GC sequences, usually between the G and C; cleavage is not very efficient, nor is cleavage required to inhibit protein synthesis. U
>>>
pon expression in situ, in M.smegmatis or E.coli inhibits cell growth and colony formation; in at least E.coli also causes increased levels of cellular RNA. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB4.
 vapC4 ELISA Kit
 vapC4 Recombinant
 vapC4 Antibody
 Rv0595c ELISA Kit
 Rv0595c Recombinant
 Rv0595c Antibody
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Toxin YhaV

 Toxin YhaV ELISA Kit
 Toxin YhaV Recombinant
 Toxin YhaV Antibody
Also known as Toxin YhaV (Ribonuclease YhaV).
Toxic component of a toxin-antitoxin (TA) module. Has RNase activity in vitro. Overexpression leads to growth arrest after 30 minutes; these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon, probably negatively r
>>>
egulating its expression.
 yhaV ELISA Kit
 yhaV Recombinant
 yhaV Antibody
 b3130 ELISA Kit
 b3130 Recombinant
 b3130 Antibody
 JW3099 ELISA Kit
 JW3099 Recombinant
 JW3099 Antibody
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Toxin YkfI

 Toxin YkfI ELISA Kit
 Toxin YkfI Recombinant
 Toxin YkfI Antibody
Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation; these effects are overcome by concomitant expression of antitoxin YafW, which leads to toxin loss by an unknown mechanism.
 ykfI ELISA Kit
 ykfI Recombinant
 ykfI Antibody
 b0245 ELISA Kit
 b0245 Recombinant
 b0245 Antibody
 JW0234 ELISA Kit
 JW0234 Recombinant
 JW0234 Antibody
Table BarTOPTable Bar
 

Toxin YoeB

 Toxin YoeB ELISA Kit
 Toxin YoeB Recombinant
 Toxin YoeB Antibody
Also known as Toxin YoeB (Endoribonuclease YoeB) (Putative mRNA interferase YoeB).
Toxic component of a toxin-antitoxin (TA) module. Has RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides ().
 yoeB ELISA Kit
 yoeB Recombinant
 yoeB Antibody
 ssr2754.1 ELISA Kit
 ssr2754.1 Recombinant
 ssr2754.1 Antibody
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Toxin zeta

 Toxin zeta ELISA Kit
 Toxin zeta Recombinant
 Toxin zeta Antibody
Also known as Toxin zeta (UDP-N-acetylglucosamine kinase) (UNAG kinase).
Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group
>>>
of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death ().
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Toxin-5

 Toxin-5 ELISA Kit
 Toxin-5 Recombinant
 Toxin-5 Antibody
Also known as Toxin-5 (Tityustoxin V) (Ts V) (TsV) (Toxin V).
Binds voltage-dependently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking
>>>
neuronal transmission. This toxin is active against mammals (mice).
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Toxin-like TcoNTxP1

 Toxin-like TcoNTxP1 ELISA Kit
 Toxin-like TcoNTxP1 Recombinant
 Toxin-like TcoNTxP1 Antibody
Also known as Toxin-like TcoNTxP1 (Insect-like toxic peptide Tco 38.32-2) (PT-alpha* NaTx4.5).
This protein is not toxic. It induces an immune response similar to that induced by whole venom. Thus,
>>>
polyclonal antibodies raised against this protein can neutralize the effects of the venom ().
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Proteins Root Name Listing
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