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Transcriptional coactivator

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Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3 (By similarity).

Below are the list of possible Transcriptional coactivator products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Transcriptional coactivator hfi1

 Transcriptional coactivator hfi1 ELISA Kit
 Transcriptional coactivator hfi1 Recombinant
 Transcriptional coactivator hfi1 Antibody
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter
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selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3 ().
 hfi1 ELISA Kit
 hfi1 Recombinant
 hfi1 Antibody
 SPBC887.18c ELISA Kit
 SPBC887.18c Recombinant
 SPBC887.18c Antibody
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Transcriptional coactivator HFI1/ADA1

 Transcriptional coactivator HFI1/ADA1 ELISA Kit
 Transcriptional coactivator HFI1/ADA1 Recombinant
 Transcriptional coactivator HFI1/ADA1 Antibody
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (
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GCN5) and deubiquitination (UBP8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus. HFI1/ADA1 and SPT20/ADA5 may recruit TATA binding protein (TBP) and possibly other basal factors to bind to the TATA box.
 HFI1 ELISA Kit
 HFI1 Recombinant
 HFI1 Antibody
 ADA1 ELISA Kit
 ADA1 Recombinant
 ADA1 Antibody
 SUP110 ELISA Kit
 SUP110 Recombinant
 SUP110 Antibody
 YPL254W ELISA Kit
 YPL254W Recombinant
 YPL254W Antibody
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Transcriptional coactivator YAP1

 Transcriptional coactivator YAP1 ELISA Kit
 Transcriptional coactivator YAP1 Recombinant
 Transcriptional coactivator YAP1 Antibody
Also known as Transcriptional coactivator YAP1 (Yes-associated protein 1) (65 kDa Yes-associated protein) (YAP65) (Protein yorkie homolog).
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferatio
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n and promoting apoptosis (). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation ().
 YAP1 ELISA Kit
 YAP1 Recombinant
 YAP1 Antibody
 YAP65 ELISA Kit
 YAP65 Recombinant
 YAP65 Antibody
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Transcriptional coactivator YAP1-A

 Transcriptional coactivator YAP1-A ELISA Kit
 Transcriptional coactivator YAP1-A Recombinant
 Transcriptional coactivator YAP1-A Antibody
Also known as Transcriptional coactivator YAP1-A (Yes-associated protein 1-A) (xYAP) (Protein yorkie homolog-A) (Yes-associated protein YAP65 homolog A).
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restrictin
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g proliferation and promoting apoptosis (). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (). Required for expansion of the neural plate and neural plate border zone progenitor pools. Acts as a direct regulator of pax3 expression via interaction with tead1 (PubMed:21687713).
 yap1-a ELISA Kit
 yap1-a Recombinant
 yap1-a Antibody
 yap ELISA Kit
 yap Recombinant
 yap Antibody
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Transcriptional coactivator YAP1-B

 Transcriptional coactivator YAP1-B ELISA Kit
 Transcriptional coactivator YAP1-B Recombinant
 Transcriptional coactivator YAP1-B Antibody
Also known as Transcriptional coactivator YAP1-B (Yes-associated protein 1-B) (Protein yorkie homolog-B) (Yes-associated protein YAP65 homolog B).
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proli
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feration and promoting apoptosis (). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation ().
 yap1-b ELISA Kit
 yap1-b Recombinant
 yap1-b Antibody
 yap1 ELISA Kit
 yap1 Recombinant
 yap1 Antibody
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Transcriptional coactivator yorkie

 Transcriptional coactivator yorkie ELISA Kit
 Transcriptional coactivator yorkie Recombinant
 Transcriptional coactivator yorkie Antibody
Also known as Transcriptional coactivator yorkie (Protein yorkie) (Transcriptional coactivator YAP1 homolog).
Transcriptional coactivator which is the critical downstream regulatory target in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is compose
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d of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam. Regulates the expression of G1/S-specific cyclin-E (CycE) and apoptosis 1 inhibitor (th), thereby promoting cell proliferation and inhibiting apoptosis. Required for transcriptional activity of scalloped (sd) in wing imaginal disks. Induces expression of expression of vestigial (vg) in wing and haltere disks and the expression of transcription factor E2f (E2f).
 yki ELISA Kit
 yki Recombinant
 yki Antibody
 CG4005 ELISA Kit
 CG4005 Recombinant
 CG4005 Antibody
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