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Treslin

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Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation (By similarity).

Below are the list of possible Treslin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Treslin

 Treslin ELISA Kit
 Treslin Recombinant
 Treslin Antibody
Also known as Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein).
TICRR: Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition fro
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m pre-replication complex (pre-RC) to pre- initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. Belongs to the treslin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; DNA replication

Cellular Component: nucleoplasm; nucleus

Molecular Function: chromatin binding

Biological Process: regulation of DNA replication initiation
 Ticrr ELISA Kit
 Ticrr Recombinant
 Ticrr Antibody
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