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tRNA nuclease

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Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. The C-terminal 160 residues (CT domain) acts as a general tRNA nuclease, and inhibits growth in E.coli. Cleaves specifically within the T-loop of E.coli tRNA2(Arg). Toxic activity is neutralized by coexpression of the cognate immunity protein CdiI in E.coli, but not by non-cognate immunity proteins from other strains of B.pseudomallei.

Below are the list of possible tRNA nuclease products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

tRNA nuclease CdiA

 tRNA nuclease CdiA ELISA Kit
 tRNA nuclease CdiA Recombinant
 tRNA nuclease CdiA Antibody
Also known as tRNA nuclease CdiA (Toxin CdiA).
Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. The C-terminal 160 residues (CT domain) acts as a general tRNA nuclease, and
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inhibits growth in E.coli. Cleaves specifically within the T-loop of E.coli tRNA2(Arg). Toxic activity is neutralized by coexpression of the cognate immunity protein CdiI in E.coli, but not by non-cognate immunity proteins from other strains of B.pseudomallei.
 cdiA ELISA Kit
 cdiA Recombinant
 cdiA Antibody
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tRNA nuclease CdiA-2

 tRNA nuclease CdiA-2 ELISA Kit
 tRNA nuclease CdiA-2 Recombinant
 tRNA nuclease CdiA-2 Antibody
Also known as tRNA nuclease CdiA-2 (tRNase CdiA-2) (Toxin CdiA-2) (Toxin CdiA-II).
Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. The C-terminal 301 residues (the CT frag
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ment) cleaves near the C-terminus of E.coli tRNA1B(Ala), probably preventing tRNA charging, and inhibits growth in E.coli. A truncated CT fragment (residues 2948-3122) has tRNA endonuclease activity on several B.thailandensis tRNAs as well as tRNA2(Arg) where it cleaves after A-70 and U-71. Toxic activity is neutralized by coexpression of the cognate immunity protein CdiI in E.coli, but not by non-cognate immunity proteins from other strains of B.pseudomallei.
 cdiA2 ELISA Kit
 cdiA2 Recombinant
 cdiA2 Antibody
 BP1026B_II2207 ELISA Kit
 BP1026B_II2207 Recombinant
 BP1026B_II2207 Antibody
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tRNA nuclease WapA

 tRNA nuclease WapA ELISA Kit
 tRNA nuclease WapA Recombinant
 tRNA nuclease WapA Antibody
Also known as tRNA nuclease WapA (Cell wall-associated polypeptide CWBP200) (CWBP200) (RNase WapA) (Toxin WapA) (Wall-associated protein).
Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. A site-specific general tRNA nuclease, the C-terminus (residues 2201-2334) removes 2 or 4 nucleotides from the 3' end of at least 4 tRNAs (upon expression in E.coli), possibly endonucleolytically. The nuclease activity is neutralized by expression of the cognate immunity protein WapI from the same strain, but not its homolog
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from 2 other B.subtilis strains. The C-terminus cannot be expressed on its own in E.coli, however it can be cloned in the presence of its cognate immunity protein gene. Cell contact is necessary for growth inhibition.
 wapA ELISA Kit
 wapA Recombinant
 wapA Antibody
 BSU39230 ELISA Kit
 BSU39230 Recombinant
 BSU39230 Antibody
 N17G ELISA Kit
 N17G Recombinant
 N17G Antibody
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