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Tumor necrosis factor receptor superfamily

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Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Below are the list of possible Tumor necrosis factor receptor superfamily products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Tumor necrosis factor receptor superfamily member 10A

 Tumor necrosis factor receptor superfamily member 10A ELISA Kit
 Tumor necrosis factor receptor superfamily member 10A Recombinant
 Tumor necrosis factor receptor superfamily member 10A Antibody
Also known as Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261).
TRAIL-R1: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B.

Protein type: Membrane
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protein, integral

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: cell surface; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: death receptor activity; protease binding; protein binding; transcription factor binding; tumor necrosis factor receptor activity

Biological Process: caspase activation; cell surface receptor linked signal transduction; immune response; inflammatory response; multicellular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; signal transduction
 TNFRSF10A ELISA Kit
 TNFRSF10A Recombinant
 TNFRSF10A Antibody
 APO2 ELISA Kit
 APO2 Recombinant
 APO2 Antibody
 DR4 ELISA Kit
 DR4 Recombinant
 DR4 Antibody
 TRAILR1 ELISA Kit
 TRAILR1 Recombinant
 TRAILR1 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 10B

 Tumor necrosis factor receptor superfamily member 10B ELISA Kit
 Tumor necrosis factor receptor superfamily member 10B Recombinant
 Tumor necrosis factor receptor superfamily member 10B Antibody
Also known as Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (MK) (CD antigen CD262).
TRAIL-R1: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B.

Protein type: Membrane protein, integral

Cellular Component: cell surface; integral to plasm
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a membrane; membrane

Molecular Function: caspase activator activity; protease binding; TRAIL binding; transcription factor binding; tumor necrosis factor receptor activity

Biological Process: apoptosis; immune response; induction of apoptosis via death domain receptors; inflammatory response; multicellular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
 Tnfrsf10b ELISA Kit
 Tnfrsf10b Recombinant
 Tnfrsf10b Antibody
 Dr5 ELISA Kit
 Dr5 Recombinant
 Dr5 Antibody
 Killer ELISA Kit
 Killer Recombinant
 Killer Antibody
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Tumor necrosis factor receptor superfamily member 10C

 Tumor necrosis factor receptor superfamily member 10C ELISA Kit
 Tumor necrosis factor receptor superfamily member 10C Recombinant
 Tumor necrosis factor receptor superfamily member 10C Antibody
Also known as Tumor necrosis factor receptor superfamily member 10C (Antagonist decoy receptor for TRAIL/Apo-2L) (Decoy TRAIL receptor without death domain) (Decoy receptor 1) (DcR1) (Lymphocyte inhibitor of TRAIL) (TNF-related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (TRAIL receptor without an intracellular domain) (CD antigen CD263).
TRAIL-R3: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to
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the ligand. Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 8p22-p21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity; tumor necrosis factor receptor activity

Biological Process: immune response; induction of apoptosis via death domain receptors; inflammatory response; multicellular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; signal transduction
 TNFRSF10C ELISA Kit
 TNFRSF10C Recombinant
 TNFRSF10C Antibody
 DCR1 ELISA Kit
 DCR1 Recombinant
 DCR1 Antibody
 LIT ELISA Kit
 LIT Recombinant
 LIT Antibody
 TRAILR3 ELISA Kit
 TRAILR3 Recombinant
 TRAILR3 Antibody
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Tumor necrosis factor receptor superfamily member 10D

 Tumor necrosis factor receptor superfamily member 10D ELISA Kit
 Tumor necrosis factor receptor superfamily member 10D Recombinant
 Tumor necrosis factor receptor superfamily member 10D Antibody
Also known as Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264).
TRAIL-R4: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce t
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he NF-kappa-B pathway. Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: transmembrane receptor activity; tumor necrosis factor receptor activity

Biological Process: immune response; induction of apoptosis via death domain receptors; inflammatory response; multicellular organismal development; negative regulation of apoptosis; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; signal transduction
 TNFRSF10D ELISA Kit
 TNFRSF10D Recombinant
 TNFRSF10D Antibody
 DCR2 ELISA Kit
 DCR2 Recombinant
 DCR2 Antibody
 TRAILR4 ELISA Kit
 TRAILR4 Recombinant
 TRAILR4 Antibody
 TRUNDD ELISA Kit
 TRUNDD Recombinant
 TRUNDD Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 11A

 Tumor necrosis factor receptor superfamily member 11A ELISA Kit
 Tumor necrosis factor receptor superfamily member 11A Recombinant
 Tumor necrosis factor receptor superfamily member 11A Antibody
Also known as Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor) (ODFR) (Receptor activator of NF-KB) (CD antigen CD265).
TNFRSF11A: Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. Binds to the clefts between the subunits of the
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TNFSF11 ligand trimer to form a heterohexamer. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Interacts (via cytoplasmic domain) with GAB2. Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q22.1

Cellular Component: external side of plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: cytokine binding; protein binding; receptor activity; transmembrane receptor activity; tumor necrosis factor receptor activity

Biological Process: activation of NF-kappaB transcription factor; adaptive immune response; cell-cell signaling; circadian thermoregulation; inflammatory response; osteoclast differentiation; positive regulation of cell proliferation; positive regulation of JNK activity; positive regulation of transcription factor activity; regulation of apoptosis; response to cytokine stimulus; response to lipopolysaccharide; signal transduction; tumor necrosis factor-mediated signaling pathway

Disease: Familial Expansile Osteolysis; Osteopetrosis, Autosomal Recessive 7; Paget Disease Of Bone
 TNFRSF11A ELISA Kit
 TNFRSF11A Recombinant
 TNFRSF11A Antibody
 RANK ELISA Kit
 RANK Recombinant
 RANK Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 11B

 Tumor necrosis factor receptor superfamily member 11B ELISA Kit
 Tumor necrosis factor receptor superfamily member 11B Recombinant
 Tumor necrosis factor receptor superfamily member 11B Antibody
Also known as Tumor necrosis factor receptor superfamily member 11B (Osteoclastogenesis inhibitory factor) (Osteoprotegerin).
TNFRSF11B: Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. Defects in TNFRSF11B are the cause o
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f juvenile Paget disease (JPD); also known as hyperostosis corticalis deformans juvenilis or hereditary hyperphosphatasia or chronic congenital idiopathic hyperphosphatasia. JPD is a rare autosomal recessive osteopathy that presents in infancy or early childhood. The disorder is characterized by rapidly remodeling woven bone, osteopenia, debilitating fractures, and deformities due to a markedly accelerated rate of bone remodeling throughout the skeleton. Approximately 40 cases of JPD have been reported worldwide. Unless it is treated with drugs that block osteoclast- mediated skeletal resorption, the disease can be fatal.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; integral to plasma membrane; proteinaceous extracellular matrix

Molecular Function: tumor necrosis factor receptor activity

Biological Process: extracellular matrix organization and biogenesis; immune response; inflammatory response; negative regulation of bone resorption; negative regulation of odontogenesis of dentine-containing teeth; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
 Tnfrsf11b ELISA Kit
 Tnfrsf11b Recombinant
 Tnfrsf11b Antibody
 Ocif ELISA Kit
 Ocif Recombinant
 Ocif Antibody
 Opg ELISA Kit
 Opg Recombinant
 Opg Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 12A

 Tumor necrosis factor receptor superfamily member 12A ELISA Kit
 Tumor necrosis factor receptor superfamily member 12A Recombinant
 Tumor necrosis factor receptor superfamily member 12A Antibody
Also known as Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Fibroblast growth factor-regulated protein 2) (Tweak-receptor) (TweakR) (CD antigen CD266).
TweakR: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Associates with TRAF1 and TRAF2, and probably also with TRAF3. By FGF1 and phorbol ester. Highly expressed in heart, placenta and kidney. Interme
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diate expression in lung, skeletal muscle and pancreas. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.

Cellular Component: cell surface; plasma membrane; ruffle

Molecular Function: protein binding

Biological Process: cell adhesion; positive regulation of apoptosis; positive regulation of axon extension; regulation of angiogenesis; substrate-bound cell migration, cell attachment to substrate
 Tnfrsf12a ELISA Kit
 Tnfrsf12a Recombinant
 Tnfrsf12a Antibody
 Fgfrp2 ELISA Kit
 Fgfrp2 Recombinant
 Fgfrp2 Antibody
 Fn14 ELISA Kit
 Fn14 Recombinant
 Fn14 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 13B

 Tumor necrosis factor receptor superfamily member 13B ELISA Kit
 Tumor necrosis factor receptor superfamily member 13B Recombinant
 Tumor necrosis factor receptor superfamily member 13B Antibody
Also known as Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD antigen CD267).
TNFRSF13B: Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell
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function and the regulation of humoral immunity. Defects in TNFRSF13B are the cause of immunodeficiency common variable type 2 (CVID2). CVID2 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Defects in TNFRSF13B are a cause of immunoglobulin A deficiency 2 (IGAD2). Selective deficiency of immunoglobulin A (IGAD) is the most common form of primary immunodeficiency, with an incidence of approximately 1 in 600 individuals in the western world. Individuals with symptomatic IGAD often have deficiency of IgG subclasses or decreased antibody response to carbohydrate antigens such as pneumococcal polysaccharide vaccine. Individuals with IGAD also suffer from recurrent sinopulmonary and gastrointestinal infections and have an increased incidence of autoimmune disorders and of lymphoid and non-lymphoid malignancies. In vitro studies have suggested that some individuals with IGAD have impaired isotype class switching to IgA and others may have a post-switch defect. IGAD and CVID have been known to coexist in families. Some individuals initially present with IGAD1 and then develop CVID. These observations suggest that some cases of IGAD and CVID may have a common etiology. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: B cell homeostasis; cell surface receptor linked signal transduction; hemopoietic progenitor cell differentiation; negative regulation of B cell proliferation; tumor necrosis factor-mediated signaling pathway

Disease: Immunodeficiency, Common Variable, 2; Immunoglobulin A Deficiency 2
 TNFRSF13B ELISA Kit
 TNFRSF13B Recombinant
 TNFRSF13B Antibody
 TACI ELISA Kit
 TACI Recombinant
 TACI Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 13C

 Tumor necrosis factor receptor superfamily member 13C ELISA Kit
 Tumor necrosis factor receptor superfamily member 13C Recombinant
 Tumor necrosis factor receptor superfamily member 13C Antibody
Also known as Tumor necrosis factor receptor superfamily member 13C (B-cell maturation defect) (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268).
BAFF-R: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4); also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an
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inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cell surface; Membrane protein, integral; Receptor, misc.

Cellular Component: external side of plasma membrane; integral to membrane

Biological Process: B cell costimulation; B cell homeostasis; positive regulation of B cell proliferation; positive regulation of germinal center formation; positive regulation of interferon-gamma biosynthetic process; positive regulation of T cell proliferation; regulation of immune response; T cell costimulation
 Tnfrsf13c ELISA Kit
 Tnfrsf13c Recombinant
 Tnfrsf13c Antibody
 Baffr ELISA Kit
 Baffr Recombinant
 Baffr Antibody
 Bcmd ELISA Kit
 Bcmd Recombinant
 Bcmd Antibody
 Br3 ELISA Kit
 Br3 Recombinant
 Br3 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 14

 Tumor necrosis factor receptor superfamily member 14 ELISA Kit
 Tumor necrosis factor receptor superfamily member 14 Recombinant
 Tumor necrosis factor receptor superfamily member 14 Antibody
Also known as Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270).
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by Ref
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Seq, Jul 2014]
 TNFRSF14 ELISA Kit
 TNFRSF14 Recombinant
 TNFRSF14 Antibody
 HVEA ELISA Kit
 HVEA Recombinant
 HVEA Antibody
 HVEM ELISA Kit
 HVEM Recombinant
 HVEM Antibody
 UNQ329/PRO509 ELISA Kit
 UNQ329/PRO509 Recombinant
 UNQ329/PRO509 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 16

 Tumor necrosis factor receptor superfamily member 16 ELISA Kit
 Tumor necrosis factor receptor superfamily member 16 Recombinant
 Tumor necrosis factor receptor superfamily member 16 Antibody
Also known as Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD).
NGFR: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells (By similarity)

Protein type: Membrane protein, integral; R
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eceptor, misc.
 NGFR ELISA Kit
 NGFR Recombinant
 NGFR Antibody
 TNFRSF16 ELISA Kit
 TNFRSF16 Recombinant
 TNFRSF16 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 17

 Tumor necrosis factor receptor superfamily member 17 ELISA Kit
 Tumor necrosis factor receptor superfamily member 17 Recombinant
 Tumor necrosis factor receptor superfamily member 17 Antibody
Also known as Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269).
TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.

Protein type: Membrane protein, integral; Oncoprotein; Receptor, misc.

Chromosomal Location of Human Ortholog: 16p13.1

Cellular Component
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: plasma membrane

Biological Process: cell proliferation; multicellular organismal development; signal transduction; tumor necrosis factor-mediated signaling pathway
 TNFRSF17 ELISA Kit
 TNFRSF17 Recombinant
 TNFRSF17 Antibody
 BCM ELISA Kit
 BCM Recombinant
 BCM Antibody
 BCMA ELISA Kit
 BCMA Recombinant
 BCMA Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 18

 Tumor necrosis factor receptor superfamily member 18 ELISA Kit
 Tumor necrosis factor receptor superfamily member 18 Recombinant
 Tumor necrosis factor receptor superfamily member 18 Antibody
Also known as Tumor necrosis factor receptor superfamily member 18 (Activation-inducible TNFR family receptor) (Glucocorticoid-induced TNFR-related protein) (CD antigen CD357).
TNFRSF18: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Receptor, cytokine

Chromosomal Location of Human Ortholog: 1p36.3 >>>
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Cellular Component: integral to plasma membrane; plasma membrane

Biological Process: immune response; induction of apoptosis via death domain receptors; inflammatory response; multicellular organismal development; positive regulation of cell adhesion; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of Stat1 protein; regulation of cell proliferation; response to lipopolysaccharide; signal transduction; tumor necrosis factor-mediated signaling pathway
 TNFRSF18 ELISA Kit
 TNFRSF18 Recombinant
 TNFRSF18 Antibody
 AITR ELISA Kit
 AITR Recombinant
 AITR Antibody
 GITR ELISA Kit
 GITR Recombinant
 GITR Antibody
 UNQ319/PRO364 ELISA Kit
 UNQ319/PRO364 Recombinant
 UNQ319/PRO364 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 19

 Tumor necrosis factor receptor superfamily member 19 ELISA Kit
 Tumor necrosis factor receptor superfamily member 19 Recombinant
 Tumor necrosis factor receptor superfamily member 19 Antibody
Also known as Tumor necrosis factor receptor superfamily member 19 (TRADE) (Toxicity and JNK inducer).
TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: plasma membrane

Molecular Function: receptor activity

Biological Process: hair follicle development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade
 Tnfrsf19 ELISA Kit
 Tnfrsf19 Recombinant
 Tnfrsf19 Antibody
 Taj ELISA Kit
 Taj Recombinant
 Taj Antibody
 Troy ELISA Kit
 Troy Recombinant
 Troy Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 19L

 Tumor necrosis factor receptor superfamily member 19L ELISA Kit
 Tumor necrosis factor receptor superfamily member 19L Recombinant
 Tumor necrosis factor receptor superfamily member 19L Antibody
RELT: Mediates activation of NF-kappa-B. May play a role in T- cell activation. Belongs to the RELT family.

Protein type: Membrane protein, integral

Cellular Component: integral to plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: immune response; inflammatory response; multicellular organismal development; positive regulati
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on of MAPKKK cascade; programmed cell death; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
 Relt ELISA Kit
 Relt Recombinant
 Relt Antibody
 Tnfrsf19l ELISA Kit
 Tnfrsf19l Recombinant
 Tnfrsf19l Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 1A

 Tumor necrosis factor receptor superfamily member 1A ELISA Kit
 Tumor necrosis factor receptor superfamily member 1A Recombinant
 Tumor necrosis factor receptor superfamily member 1A Antibody
Also known as Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a).
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DI
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SC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis ().
 TNFRSF1A ELISA Kit
 TNFRSF1A Recombinant
 TNFRSF1A Antibody
 TNFR1 ELISA Kit
 TNFR1 Recombinant
 TNFR1 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 1B

 Tumor necrosis factor receptor superfamily member 1B ELISA Kit
 Tumor necrosis factor receptor superfamily member 1B Recombinant
 Tumor necrosis factor receptor superfamily member 1B Antibody
Also known as Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b).
TNF-R2: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it reg
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ulates TNF-alpha function by antagonizing its biological activity. Binds to TRAF2. Interacts with BMX. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: axon; cell soma; integral to plasma membrane; lipid raft; membrane; nucleus; perinuclear region of cytoplasm

Molecular Function: protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: cell proliferation; cell surface receptor linked signal transduction; DNA damage response, signal transduction resulting in induction of apoptosis; immune response; inflammatory response; multicellular organismal development; negative regulation of inflammatory response; positive regulation of MAPKKK cascade; positive regulation of membrane protein ectodomain proteolysis; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; RNA destabilization
 Tnfrsf1b ELISA Kit
 Tnfrsf1b Recombinant
 Tnfrsf1b Antibody
 Tnfr-2 ELISA Kit
 Tnfr-2 Recombinant
 Tnfr-2 Antibody
 Tnfr2 ELISA Kit
 Tnfr2 Recombinant
 Tnfr2 Antibody
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Tumor necrosis factor receptor superfamily member 21

 Tumor necrosis factor receptor superfamily member 21 ELISA Kit
 Tumor necrosis factor receptor superfamily member 21 Recombinant
 Tumor necrosis factor receptor superfamily member 21 Antibody
Also known as Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358).
Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid pepti
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des derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21; this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. Negatively regulates T-cell responses and the release of cytokines such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells. Negatively regulates the production of IgG, IgM and IgM in response to antigens. May inhibit the activation of JNK in response to T-cell stimulation (). Negatively regulates oligodendrocyte survival, maturation and myelination.
 Tnfrsf21 ELISA Kit
 Tnfrsf21 Recombinant
 Tnfrsf21 Antibody
 Dr6 ELISA Kit
 Dr6 Recombinant
 Dr6 Antibody
Table BarTOPTable Bar
 

Tumor necrosis factor receptor superfamily member 22

 Tumor necrosis factor receptor superfamily member 22 ELISA Kit
 Tumor necrosis factor receptor superfamily member 22 Recombinant
 Tumor necrosis factor receptor superfamily member 22 Antibody
Also known as Tumor necrosis factor receptor superfamily member 22 (Decoy TRAIL receptor 2) (TNF receptor family member SOBa) (TNF receptor homolog 2) (Tumor necrosis factor receptor p60 homolog 2).
TNFRSF22: Receptor for the cytotoxic ligand TNFSF10/TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis possibly through ligand competition. Cannot induce the NF-kappa-B pathway.

Cellular Component: external side of plasma membrane

Molecular Function: protein binding; receptor activity; TRAIL bindin
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g
 Tnfrsf22 ELISA Kit
 Tnfrsf22 Recombinant
 Tnfrsf22 Antibody
 Dctrailr2 ELISA Kit
 Dctrailr2 Recombinant
 Dctrailr2 Antibody
 Tnfrh2 ELISA Kit
 Tnfrh2 Recombinant
 Tnfrh2 Antibody
 Tnfrsf1al2 ELISA Kit
 Tnfrsf1al2 Recombinant
 Tnfrsf1al2 Antibody
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Tumor necrosis factor receptor superfamily member 23

 Tumor necrosis factor receptor superfamily member 23 ELISA Kit
 Tumor necrosis factor receptor superfamily member 23 Recombinant
 Tumor necrosis factor receptor superfamily member 23 Antibody
Also known as Tumor necrosis factor receptor superfamily member 23 (Decoy TRAIL receptor 1) (TNF receptor family member SOB) (TNF receptor homolog 1) (Tumor necrosis factor receptor p60 homolog 1).
TNFRSF23: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis through ligand competition. Cannot induce the NF-kappa-B pathway.

Cellular Component: anchored to external side of plasma membrane

Molecular Function: protein binding
 Tnfrsf23 ELISA Kit
 Tnfrsf23 Recombinant
 Tnfrsf23 Antibody
 Dctrailr1 ELISA Kit
 Dctrailr1 Recombinant
 Dctrailr1 Antibody
 Tnfrh1 ELISA Kit
 Tnfrh1 Recombinant
 Tnfrh1 Antibody
 Tnfrsf1al1 ELISA Kit
 Tnfrsf1al1 Recombinant
 Tnfrsf1al1 Antibody
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Tumor necrosis factor receptor superfamily member 25

 Tumor necrosis factor receptor superfamily member 25 ELISA Kit
 Tumor necrosis factor receptor superfamily member 25 Recombinant
 Tumor necrosis factor receptor superfamily member 25 Antibody
Also known as Tumor necrosis factor receptor superfamily member 25 (Apo-3) (Apoptosis-inducing receptor AIR) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death receptor 3) (Lymphocyte-associated receptor of death) (LARD) (Protein WSL) (Protein WSL-1).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The s
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ignal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008]
 TNFRSF25 ELISA Kit
 TNFRSF25 Recombinant
 TNFRSF25 Antibody
 APO3 ELISA Kit
 APO3 Recombinant
 APO3 Antibody
 DDR3 ELISA Kit
 DDR3 Recombinant
 DDR3 Antibody
 DR3 ELISA Kit
 DR3 Recombinant
 DR3 Antibody
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Tumor necrosis factor receptor superfamily member 26

 Tumor necrosis factor receptor superfamily member 26 ELISA Kit
 Tumor necrosis factor receptor superfamily member 26 Recombinant
 Tumor necrosis factor receptor superfamily member 26 Antibody
Also known as Tumor necrosis factor receptor superfamily member 26 (TNF receptor homolog 3).
TNFRSF26:

Cellular Component: integral to plasma membrane; mitochondrion

Molecular Function: tumor necrosis factor binding; tumor necrosis factor receptor activity

Biological Process: immune response; induction of apoptosis via death domain receptors; inflammatory response; multice
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llular organismal development; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
 Tnfrsf26 ELISA Kit
 Tnfrsf26 Recombinant
 Tnfrsf26 Antibody
 Tnfrh3 ELISA Kit
 Tnfrh3 Recombinant
 Tnfrh3 Antibody
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Tumor necrosis factor receptor superfamily member 27

 Tumor necrosis factor receptor superfamily member 27 ELISA Kit
 Tumor necrosis factor receptor superfamily member 27 Recombinant
 Tumor necrosis factor receptor superfamily member 27 Antibody
Also known as Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).
EDA2R: Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: intracellular; plasma membrane

Molecular Function: receptor activity

Biological Process: activation of NF-kappaB transcription f
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actor; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; programmed cell death; tissue development
 Eda2r ELISA Kit
 Eda2r Recombinant
 Eda2r Antibody
 Tnfrsf27 ELISA Kit
 Tnfrsf27 Recombinant
 Tnfrsf27 Antibody
 Xedar ELISA Kit
 Xedar Recombinant
 Xedar Antibody
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Tumor necrosis factor receptor superfamily member 3

 Tumor necrosis factor receptor superfamily member 3 ELISA Kit
 Tumor necrosis factor receptor superfamily member 3 Recombinant
 Tumor necrosis factor receptor superfamily member 3 Antibody
Also known as Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor).
LTBR: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Protein type: Membrane protein, integral

Cellular Component: integral to plasma membrane

Molecular Function: protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: immune response; inflammatory response; lymph node development;
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myeloid dendritic cell differentiation; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide
 Ltbr ELISA Kit
 Ltbr Recombinant
 Ltbr Antibody
 Tnfcr ELISA Kit
 Tnfcr Recombinant
 Tnfcr Antibody
 Tnfrsf3 ELISA Kit
 Tnfrsf3 Recombinant
 Tnfrsf3 Antibody
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Tumor necrosis factor receptor superfamily member 4

 Tumor necrosis factor receptor superfamily member 4 ELISA Kit
 Tumor necrosis factor receptor superfamily member 4 Recombinant
 Tumor necrosis factor receptor superfamily member 4 Antibody
Also known as Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134).
TNFRSF4: Receptor for TNFSF4/OX40L/GP34.

Protein type: Apoptosis; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cell surface; integral t
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o plasma membrane; plasma membrane

Molecular Function: tumor necrosis factor receptor activity

Biological Process: immune response; inflammatory response; multicellular organismal development; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; positive regulation of B cell proliferation; positive regulation of immunoglobulin secretion; positive regulation of MAPKKK cascade; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; T cell proliferation; tumor necrosis factor-mediated signaling pathway

Disease: Immunodeficiency 16
 TNFRSF4 ELISA Kit
 TNFRSF4 Recombinant
 TNFRSF4 Antibody
 TXGP1L ELISA Kit
 TXGP1L Recombinant
 TXGP1L Antibody
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Tumor necrosis factor receptor superfamily member 5

 Tumor necrosis factor receptor superfamily member 5 ELISA Kit
 Tumor necrosis factor receptor superfamily member 5 Recombinant
 Tumor necrosis factor receptor superfamily member 5 Antibody
Also known as Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CD antigen CD40).
CD40: a member of the TNF-receptor superfamily. This receptor for CD40L mediates a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. Defect
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s in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3). HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. Two alternatively spliced isoforms have been reported. Isoform I is a type I membrane protein; isoform II is secreted.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: cell soma; cell surface; cytoplasm; external side of plasma membrane; extracellular space; intracellular membrane-bound organelle; plasma membrane

Molecular Function: antigen binding; enzyme binding; protein binding; protein domain specific binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: activation of NF-kappaB transcription factor; B cell activation; cellular calcium ion homeostasis; defense response to protozoan; defense response to virus; immune response-regulating cell surface receptor signaling pathway; inflammatory response; positive regulation of B cell proliferation; positive regulation of GTPase activity; positive regulation of interleukin-12 production; positive regulation of isotype switching to IgG isotypes; positive regulation of MAP kinase activity; positive regulation of MAPKKK cascade; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of tyrosine phosphorylation of Stat1 protein; protein kinase B signaling cascade; regulation of apoptosis; regulation of immune response; regulation of immunoglobulin secretion; response to lipopolysaccharide
 Cd40 ELISA Kit
 Cd40 Recombinant
 Cd40 Antibody
 Tnfrsf5 ELISA Kit
 Tnfrsf5 Recombinant
 Tnfrsf5 Antibody
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Tumor necrosis factor receptor superfamily member 6

 Tumor necrosis factor receptor superfamily member 6 ELISA Kit
 Tumor necrosis factor receptor superfamily member 6 Recombinant
 Tumor necrosis factor receptor superfamily member 6 Antibody
Also known as Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95).
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cel
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ls, or both ().
 FAS ELISA Kit
 FAS Recombinant
 FAS Antibody
 APT1 ELISA Kit
 APT1 Recombinant
 APT1 Antibody
 TNFRSF6 ELISA Kit
 TNFRSF6 Recombinant
 TNFRSF6 Antibody
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Tumor necrosis factor receptor superfamily member 6B

 Tumor necrosis factor receptor superfamily member 6B ELISA Kit
 Tumor necrosis factor receptor superfamily member 6B Recombinant
 Tumor necrosis factor receptor superfamily member 6B Antibody
Also known as Tumor necrosis factor receptor superfamily member 6B (Decoy receptor 3) (DcR3) (Decoy receptor for Fas ligand) (M68).
TNFRSF6B: Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of
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Human Ortholog: 20q13.3

Cellular Component: extracellular region; integral to plasma membrane

Molecular Function: protein binding; receptor activity; tumor necrosis factor receptor activity

Biological Process: immune response; inflammatory response; multicellular organismal development; negative regulation of apoptosis; positive regulation of MAPKKK cascade; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway
 TNFRSF6B ELISA Kit
 TNFRSF6B Recombinant
 TNFRSF6B Antibody
 DCR3 ELISA Kit
 DCR3 Recombinant
 DCR3 Antibody
 TR6 ELISA Kit
 TR6 Recombinant
 TR6 Antibody
 UNQ186/PRO212 ELISA Kit
 UNQ186/PRO212 Recombinant
 UNQ186/PRO212 Antibody
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Tumor necrosis factor receptor superfamily member 8

 Tumor necrosis factor receptor superfamily member 8 ELISA Kit
 Tumor necrosis factor receptor superfamily member 8 Recombinant
 Tumor necrosis factor receptor superfamily member 8 Antibody
Also known as Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect
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the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
 TNFRSF8 ELISA Kit
 TNFRSF8 Recombinant
 TNFRSF8 Antibody
 CD30 ELISA Kit
 CD30 Recombinant
 CD30 Antibody
 D1S166E ELISA Kit
 D1S166E Recombinant
 D1S166E Antibody
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Tumor necrosis factor receptor superfamily member 9

 Tumor necrosis factor receptor superfamily member 9 ELISA Kit
 Tumor necrosis factor receptor superfamily member 9 Recombinant
 Tumor necrosis factor receptor superfamily member 9 Antibody
Also known as Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TR
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AF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
 TNFRSF9 ELISA Kit
 TNFRSF9 Recombinant
 TNFRSF9 Antibody
 CD137 ELISA Kit
 CD137 Recombinant
 CD137 Antibody
 ILA ELISA Kit
 ILA Recombinant
 ILA Antibody
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Tumor necrosis factor receptor superfamily member EDAR

 Tumor necrosis factor receptor superfamily member EDAR ELISA Kit
 Tumor necrosis factor receptor superfamily member EDAR Recombinant
 Tumor necrosis factor receptor superfamily member EDAR Antibody
Also known as Tumor necrosis factor receptor superfamily member EDAR (Anhidrotic ectodysplasin receptor 1) (Downless homolog) (EDA-A1 receptor) (Ectodermal dysplasia receptor) (Ectodysplasin-A receptor).
EDAR: Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. Defects in EDAR are a cause of ectoderm
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al dysplasia anhidrotic (EDA); also known ectodermal dysplasia hypohidrotic autosomal recessive (HED). Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EDA is characterized by sparse hair (atrichosis or hypotrichosis), abnormal or missing teeth and the inability to sweat due to the absence of sweat glands. Defects in EDAR are the cause of ectodermal dysplasia type 3 (ED3); also known as ectodermal dysplasia hypohidrotic autosomal dominant or EDA3. ED3 is an autosomal dominant condition characterized by hypotrichosis, abnormal or missing teeth, and hypohidrosis due to the absence of sweat glands.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: epidermis development; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; tumor necrosis factor-mediated signaling pathway

Disease: Ectodermal Dysplasia 10a, Hypohidrotic/hair/nail Type, Autosomal Dominant; Ectodermal Dysplasia 10b, Hypohidrotic/hair/tooth Type, Autosomal Recessive; Hair Morphology 1
 EDAR ELISA Kit
 EDAR Recombinant
 EDAR Antibody
 DL ELISA Kit
 DL Recombinant
 DL Antibody
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Tumor necrosis factor receptor superfamily member wengen

 Tumor necrosis factor receptor superfamily member wengen ELISA Kit
 Tumor necrosis factor receptor superfamily member wengen Recombinant
 Tumor necrosis factor receptor superfamily member wengen Antibody
Receptor for egr (PubMed:12084706, PubMed:12894227). Involved in induction of apoptosis by triggering JNK signaling (PubMed:12894227). Mediates the tumor suppressor activity of egr which eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity (PubMed:19289090). Following UV-induced epidermal damage, binds to egr released from apoptotic epidermal cells and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious (PubMed:19375319). Together with Moe, involved in control of axon targe
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ting of R8 and R2-R5 photoreceptors, independent of egr (PubMed:23544124).
 wgn ELISA Kit
 wgn Recombinant
 wgn Antibody
 Vader ELISA Kit
 Vader Recombinant
 Vader Antibody
 CG6531 ELISA Kit
 CG6531 Recombinant
 CG6531 Antibody
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Proteins Root Name Listing
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