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Twisted gastrulation protein

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May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.

Below are the list of possible Twisted gastrulation protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Twisted gastrulation protein homolog 1

 Twisted gastrulation protein homolog 1 ELISA Kit
 Twisted gastrulation protein homolog 1 Recombinant
 Twisted gastrulation protein homolog 1 Antibody
TWSG1: May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regula
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ted cartilage development and chondrocyte differentiation. May play a role in thymocyte development. Belongs to the twisted gastrulation protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: protein binding

Biological Process: BMP signaling pathway; camera-type eye development; cell differentiation; embryonic development; forebrain development; hemopoiesis; mesoderm formation; negative regulation of BMP signaling pathway; negative regulation of osteoblast differentiation; ossification; positive regulation of BMP signaling pathway; salivary gland morphogenesis; tissue development
 Twsg1 ELISA Kit
 Twsg1 Recombinant
 Twsg1 Antibody
 Tsg ELISA Kit
 Tsg Recombinant
 Tsg Antibody
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Twisted gastrulation protein homolog 1-A

 Twisted gastrulation protein homolog 1-A ELISA Kit
 Twisted gastrulation protein homolog 1-A Recombinant
 Twisted gastrulation protein homolog 1-A Antibody
Involved in dorsal-ventral patterning. Appears to function predominantly as a ventralizing factor, through its actions as a BMP signaling agonist, acting through both chd-dependent and chd-independent mechanisms. May also antagonize BMP signaling, probably via formation of ternary complexes with chd and BMPs, resulting in dorsalization ().
 twsg1a ELISA Kit
 twsg1a Recombinant
 twsg1a Antibody
 tsg ELISA Kit
 tsg Recombinant
 tsg Antibody
 twsg1 ELISA Kit
 twsg1 Recombinant
 twsg1 Antibody
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Twisted gastrulation protein homolog 1-B

 Twisted gastrulation protein homolog 1-B ELISA Kit
 Twisted gastrulation protein homolog 1-B Recombinant
 Twisted gastrulation protein homolog 1-B Antibody
Involved in dorsal-ventral patterning. Appears to function predominantly as a ventralizing factor, through its actions as a BMP signaling agonist, acting through both chd-dependent and chd-independent mechanisms. May also antagonize BMP signaling, probably via formation of ternary complexes with chd and BMPs, resulting in dorsalization.
 twsg1b ELISA Kit
 twsg1b Recombinant
 twsg1b Antibody
 tsg1 ELISA Kit
 tsg1 Recombinant
 tsg1 Antibody
 tsgb ELISA Kit
 tsgb Recombinant
 tsgb Antibody
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