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Tyrosyl-DNA phosphodiesterase

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DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue.

Below are the list of possible Tyrosyl-DNA phosphodiesterase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Tyrosyl-DNA phosphodiesterase 1

 Tyrosyl-DNA phosphodiesterase 1 ELISA Kit
 Tyrosyl-DNA phosphodiesterase 1 Recombinant
 Tyrosyl-DNA phosphodiesterase 1 Antibody
Also known as Tyrosyl-DNA phosphodiesterase 1 (AtTDP) (Tyr-DNA phosphodiesterase 1).
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue.
 TDP1 ELISA Kit
 TDP1 Recombinant
 TDP1 Antibody
 At5g15170 ELISA Kit
 At5g15170 Recombinant
 At5g15170 Antibody
 F8M21.60 ELISA Kit
 F8M21.60 Recombinant
 F8M21.60 Antibody
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Tyrosyl-DNA phosphodiesterase 2

 Tyrosyl-DNA phosphodiesterase 2 ELISA Kit
 Tyrosyl-DNA phosphodiesterase 2 Recombinant
 Tyrosyl-DNA phosphodiesterase 2 Antibody
Also known as Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase).
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2
>>>
) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1.
 TDP2 ELISA Kit
 TDP2 Recombinant
 TDP2 Antibody
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