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U18-theraphotoxin

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Inhibits TTX-sensitive and TTX-insensitive sodium currents (IC(50) is 0.6 uM and 0.95 uM respectively) on rat dorsal root ganglion (DRG) neurons .

Below are the list of possible U18-theraphotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

U18-theraphotoxin-Cg1a

 U18-theraphotoxin-Cg1a ELISA Kit
 U18-theraphotoxin-Cg1a Recombinant
 U18-theraphotoxin-Cg1a Antibody
Also known as U18-theraphotoxin-Cg1a (U18-TRTX-Cg1a) (Jingzhaotoxin-32) (JZTX-32) (Jingzhaotoxin-9) (JzTx-9) (Jingzhaotoxin-IX) (JzTx-IX) (Peptide F6-16.24).
Inhibits TTX-sensitive and TTX-insensit
>>>
ive sodium currents (IC50 is 0.6 µM and 0.95 µM respectively) on rat dorsal root ganglion (DRG) neurons (PubMed:18581053, PubMed:19409400). Inhibits muscular subtypes sodium channels Nav1.4/SCN4A and Nav1.5/SCN5A transiently transfected in to HEK293 cells (IC50 is 5.42 µM and 0.45 µM respectively). Also blocks Kv2.1/KCNB1 potassium channels expressed in X.laevis oocytes with an IC50 of 604 nM. Injection of the toxin in mice was immediately followed by general ataxia, lack of response to stimuli and semiparalysis (PubMed:19409400).
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