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U3-agatoxin

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Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV. Compared to beta/delta-agatoxin-1 to -3, this toxin appears to affect the insect sodium channel only weakly.

Below are the list of possible U3-agatoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

U3-agatoxin-Ao1a

 U3-agatoxin-Ao1a ELISA Kit
 U3-agatoxin-Ao1a Recombinant
 U3-agatoxin-Ao1a Antibody
Also known as U3-agatoxin-Ao1a (U3-AGTX-Ao1a) (Beta/delta-agatoxin-7) (Mu-2Aga_01).
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with
>>>
both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV. Compared to beta/delta-agatoxin-1 to -3, this toxin appears to affect the insect sodium channel only weakly.
Table BarTOPTable Bar
 

U3-agatoxin-Ao1b

 U3-agatoxin-Ao1b ELISA Kit
 U3-agatoxin-Ao1b Recombinant
 U3-agatoxin-Ao1b Antibody
Also known as U3-agatoxin-Ao1b (U3-AGTX-Ao1b) (Mu-2Aga_03).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated sod
>>>
ium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1c

 U3-agatoxin-Ao1c ELISA Kit
 U3-agatoxin-Ao1c Recombinant
 U3-agatoxin-Ao1c Antibody
Also known as U3-agatoxin-Ao1c (U3-AGTX-Ao1c) (Beta/delta-agatoxin-3) (Mu-2Aga_04).
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with
>>>
both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV.
Table BarTOPTable Bar
 

U3-agatoxin-Ao1d

 U3-agatoxin-Ao1d ELISA Kit
 U3-agatoxin-Ao1d Recombinant
 U3-agatoxin-Ao1d Antibody
Also known as U3-agatoxin-Ao1d (U3-AGTX-Ao1d) (Mu-2Aga_05).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated sod
>>>
ium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1e

 U3-agatoxin-Ao1e ELISA Kit
 U3-agatoxin-Ao1e Recombinant
 U3-agatoxin-Ao1e Antibody
Also known as U3-agatoxin-Ao1e (U3-AGTX-Ao1e) (Mu-2Aga_06).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated sod
>>>
ium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1f

 U3-agatoxin-Ao1f ELISA Kit
 U3-agatoxin-Ao1f Recombinant
 U3-agatoxin-Ao1f Antibody
Also known as U3-agatoxin-Ao1f (U3-AGTX-Ao1f) (Beta/delta-agatoxin-1) (Mu-2Aga_07).
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with
>>>
both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV. In vivo, induces an irreversible spastic paralysis when injected into insects.
Table BarTOPTable Bar
 

U3-agatoxin-Ao1g

 U3-agatoxin-Ao1g ELISA Kit
 U3-agatoxin-Ao1g Recombinant
 U3-agatoxin-Ao1g Antibody
Also known as U3-agatoxin-Ao1g (U3-AGTX-Ao1g) (Beta/delta-agatoxin-2) (Mu-2Aga_08).
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with
>>>
both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV.
Table BarTOPTable Bar
 

U3-agatoxin-Ao1h

 U3-agatoxin-Ao1h ELISA Kit
 U3-agatoxin-Ao1h Recombinant
 U3-agatoxin-Ao1h Antibody
Also known as U3-agatoxin-Ao1h (U3-AGTX-Ao1h) (Mu-2Aaga_09).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated so
>>>
dium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1i

 U3-agatoxin-Ao1i ELISA Kit
 U3-agatoxin-Ao1i Recombinant
 U3-agatoxin-Ao1i Antibody
Also known as U3-agatoxin-Ao1i (U3-AGTX-Ao1i) (Mu-2Aaga_10).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated so
>>>
dium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1j

 U3-agatoxin-Ao1j ELISA Kit
 U3-agatoxin-Ao1j Recombinant
 U3-agatoxin-Ao1j Antibody
Also known as U3-agatoxin-Ao1j (U3-AGTX-Ao1j) (Mu-2Aaga_11).
Insecticidal neurotoxin that induces an irreversible spastic paralysis when injected into insects. Modifies presynaptic voltage-gated so
>>>
dium channels (Nav), causing them to open at the normal resting potential of the nerve. This leads to spontaneous release of neurotransmitter and repetitive action potentials in motor neurons ().
Table BarTOPTable Bar
 

U3-agatoxin-Ao1k

 U3-agatoxin-Ao1k ELISA Kit
 U3-agatoxin-Ao1k Recombinant
 U3-agatoxin-Ao1k Antibody
Also known as U3-agatoxin-Ao1k (U3-AGTX-Ao1k) (Beta/delta-agatoxin-4) (Mu-2Aaga_12).
Insecticidal neurotoxin that modulates the insect Nav channel (DmNaV1/tipE (para/tipE)) in a unique manner, with
>>>
both the activation and inactivation processes being affected. The voltage dependence of activation is shifted toward more hyperpolarized potentials (analogous to site 4 toxins) and a non-inactivating persistent sodium current is induced (site 3-like action). Interestingly, both effects take place in a voltage-dependent manner, producing a bell-shaped curve between -80 and 0 mV. Compared to beta/delta-agatoxin-1 to -3, this toxin appears to affect the insect sodium channel only weakly.
Table BarTOPTable Bar
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