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Ubiquitin-associated and SH3 domain-containing protein

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Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.

Below are the list of possible Ubiquitin-associated and SH3 domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Ubiquitin-associated and SH3 domain-containing protein A

 Ubiquitin-associated and SH3 domain-containing protein A ELISA Kit
 Ubiquitin-associated and SH3 domain-containing protein A Recombinant
 Ubiquitin-associated and SH3 domain-containing protein A Antibody
Also known as Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1).
STS2: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on
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the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytosol

Molecular Function: protein binding
 UBASH3A ELISA Kit
 UBASH3A Recombinant
 UBASH3A Antibody
 STS2 ELISA Kit
 STS2 Recombinant
 STS2 Antibody
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Ubiquitin-associated and SH3 domain-containing protein B

 Ubiquitin-associated and SH3 domain-containing protein B ELISA Kit
 Ubiquitin-associated and SH3 domain-containing protein B Recombinant
 Ubiquitin-associated and SH3 domain-containing protein B Antibody
Also known as Ubiquitin-associated and SH3 domain-containing protein B (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2).
STS-1: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified b
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y both protein tyrosine phosphorylation and ubiquitination.

Protein type: EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 11q24.1

Molecular Function: identical protein binding; protein binding
 UBASH3B ELISA Kit
 UBASH3B Recombinant
 UBASH3B Antibody
 KIAA1959 ELISA Kit
 KIAA1959 Recombinant
 KIAA1959 Antibody
 STS1 ELISA Kit
 STS1 Recombinant
 STS1 Antibody
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