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Ubiquitin conjugation factor

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E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates presented by the ufd1-npl4-cdc48 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to downstream ERAD components, which target them to the proteasome. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.

Below are the list of possible Ubiquitin conjugation factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Ubiquitin conjugation factor E4

 Ubiquitin conjugation factor E4 ELISA Kit
 Ubiquitin conjugation factor E4 Recombinant
 Ubiquitin conjugation factor E4 Antibody
Also known as Ubiquitin conjugation factor E4 (Ubiquitin fusion degradation protein 2) (UB fusion protein 2).
E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates presented by the ufd1-npl4-cdc48 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to downstream ERAD components, which target them to the proteasome. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.
 ufd2 ELISA Kit
 ufd2 Recombinant
 ufd2 Antibody
 SPAC145.04 ELISA Kit
 SPAC145.04 Recombinant
 SPAC145.04 Antibody
 SPAC20H4.10 ELISA Kit
 SPAC20H4.10 Recombinant
 SPAC20H4.10 Antibody
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Ubiquitin conjugation factor E4 A

 Ubiquitin conjugation factor E4 A ELISA Kit
 Ubiquitin conjugation factor E4 A Recombinant
 Ubiquitin conjugation factor E4 A Antibody
Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.
 UBE4A ELISA Kit
 UBE4A Recombinant
 UBE4A Antibody
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Ubiquitin conjugation factor E4 B

 Ubiquitin conjugation factor E4 B ELISA Kit
 Ubiquitin conjugation factor E4 B Recombinant
 Ubiquitin conjugation factor E4 B Antibody
Also known as Ubiquitin conjugation factor E4 B (Homozygously deleted in neuroblastoma 1) (Ubiquitin fusion degradation protein 2).
UBE4B: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. Belongs to the ubiquitin conjugation factor E4 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 1p36.3

Cellular Component: cytoplasm; nucleus;
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ubiquitin ligase complex

Molecular Function: enzyme binding

Biological Process: ER-associated protein catabolic process; induction of apoptosis by granzyme; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process; response to UV
 UBE4B ELISA Kit
 UBE4B Recombinant
 UBE4B Antibody
 HDNB1 ELISA Kit
 HDNB1 Recombinant
 HDNB1 Antibody
 KIAA0684 ELISA Kit
 KIAA0684 Recombinant
 KIAA0684 Antibody
 UFD2 ELISA Kit
 UFD2 Recombinant
 UFD2 Antibody
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