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UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase

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Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc).

Below are the list of possible UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase

 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase ELISA Kit
 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase Recombinant
 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase Antibody
Also known as UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase (GlOGT) (O-linked GlcNAc transferase) (O-linked N-acetylglucosaminyltransferase).
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc).
 GL50803_12081 ELISA Kit
 GL50803_12081 Recombinant
 GL50803_12081 Antibody
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UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit ELISA Kit
 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Recombinant
 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Antibody
Also known as UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT).
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylg
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lucosamine (O-GlcNAc). Glycosylates a large and diverse number of proteins including histone H2B, AKT1, EZH2, PFKL, KMT2E/MLL5, MAPT/TAU and HCFC1. Can regulate their cellular processes via cross-talk between glycosylation and phosphorylation or by affecting proteolytic processing. Involved in insulin resistance in muscle and adipocyte cells via glycosylating insulin signaling components and inhibiting the 'Thr-308' phosphorylation of AKT1, enhancing IRS1 phosphorylation and attenuating insulin signaling. Involved in glycolysis regulation by mediating glycosylation of 6-phosphofructokinase PFKL, inhibiting its activity. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. Plays a key role in chromatin structure by mediating O-GlcNAcylation of 'Ser-112' of histone H2B: recruited to CpG-rich transcription start sites of active genes via its interaction with TET proteins (TET1, TET2 or TET3). As part of the NSL complex indirectly involved in acetylation of nucleosomal histone H4 on several lysine residues. O-GlcNAcylation of 'Ser-75' of EZH2 increases its stability, and facilitating the formation of H3K27me3 by the PRC2/EED-EZH2 complex. Regulates circadian oscillation of the clock genes and glucose homeostasis in the liver. Stabilizes clock proteins ARNTL/BMAL1 and CLOCK through O-glycosylation, which prevents their ubiquitination and subsequent degradation. Promotes the CLOCK-ARNTL/BMAL1-mediated transcription of genes in the negative loop of the circadian clock such as PER1/2 and CRY1/2.
 OGT ELISA Kit
 OGT Recombinant
 OGT Antibody
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