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Unconventional prefoldin RPB5 interactor

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Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region (By similarity).

Below are the list of possible Unconventional prefoldin RPB5 interactor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Unconventional prefoldin RPB5 interactor

 Unconventional prefoldin RPB5 interactor ELISA Kit
 Unconventional prefoldin RPB5 interactor Recombinant
 Unconventional prefoldin RPB5 interactor Antibody
Also known as Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein).
RMP: Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromati
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n to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein. Homodimer. Component of the URI complex that contains PFDN2, POLR2E/RPB5, RUVBL2, RUVBL1 and URI1. Interacts with PPP1CC; the interaction is phosphorylation-dependent and occurs in a growth factor-dependent manner. Interacts with PFDN2, PFDN4 and STAP1; the interactions are phosphorylation-dependent and occurs in a growth-dependent manner in the mitochondrion. Interacts (via the middle C-terminus region) with GTF2F1 and GTF2F2. Interacts with DMAP1, POLR2E/RPB5 and UXT. Ubiquitous. Expressed in ovarian cancers. Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells. Belongs to the RNA polymerase II subunit 5-mediating protein family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Cellular Component: cytoplasm; DNA-directed RNA polymerase II, core complex; intracellular membrane-bound organelle; mitochondrion; nucleus

Molecular Function: chromatin binding; phosphatase inhibitor activity; phosphoprotein binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of cell growth; regulation of transcription from RNA polymerase II promoter; response to virus
 Uri1 ELISA Kit
 Uri1 Recombinant
 Uri1 Antibody
 Nnx3 ELISA Kit
 Nnx3 Recombinant
 Nnx3 Antibody
 Ppp1r19 ELISA Kit
 Ppp1r19 Recombinant
 Ppp1r19 Antibody
 Rmp ELISA Kit
 Rmp Recombinant
 Rmp Antibody
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Unconventional prefoldin RPB5 interactor 1

 Unconventional prefoldin RPB5 interactor 1 ELISA Kit
 Unconventional prefoldin RPB5 interactor 1 Recombinant
 Unconventional prefoldin RPB5 interactor 1 Antibody
Also known as Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein).
RMP: Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chroma
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tin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein. Homodimer. Component of the URI complex that contains PFDN2, POLR2E/RPB5, RUVBL2, RUVBL1 and URI1. Interacts with PPP1CC; the interaction is phosphorylation-dependent and occurs in a growth factor-dependent manner. Interacts with PFDN2, PFDN4 and STAP1; the interactions are phosphorylation-dependent and occurs in a growth-dependent manner in the mitochondrion. Interacts (via the middle C-terminus region) with GTF2F1 and GTF2F2. Interacts with DMAP1, POLR2E/RPB5 and UXT. Ubiquitous. Expressed in ovarian cancers. Expressed strongly in skeletal muscle. Expressed weakly in brain, heart, pancreas and in prostate epithelial cells. Belongs to the RNA polymerase II subunit 5-mediating protein family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 19q12

Cellular Component: cytoplasm; DNA-directed RNA polymerase II, core complex; intracellular membrane-bound organelle; mitochondrion; nucleus

Molecular Function: chromatin binding; phosphatase inhibitor activity; phosphoprotein binding; protein binding

Biological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of cell growth; regulation of transcription from RNA polymerase II promoter; response to virus
 URI1 ELISA Kit
 URI1 Recombinant
 URI1 Antibody
 C19orf2 ELISA Kit
 C19orf2 Recombinant
 C19orf2 Antibody
 NNX3 ELISA Kit
 NNX3 Recombinant
 NNX3 Antibody
 PPP1R19 ELISA Kit
 PPP1R19 Recombinant
 PPP1R19 Antibody
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