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Uridine 5'-monophosphate synthase

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CATALYTIC ACTIVITY: Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.; CATALYTIC ACTIVITY: Orotidine 5'-phosphate = UMP + CO(2).PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.; PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.

Below are the list of possible Uridine 5'-monophosphate synthase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Uridine 5'-monophosphate synthase

 Uridine 5'-monophosphate synthase ELISA Kit
 Uridine 5'-monophosphate synthase Recombinant
 Uridine 5'-monophosphate synthase Antibody
Also known as Uridine 5'-monophosphate synthase (UMP synthase).
UMPS: Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1). A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformati
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ons and immune deficiencies. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.4.2.10; EC 4.1.1.23; Lyase; Nucleotide Metabolism - pyrimidine; Transferase; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 3q13

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: orotate phosphoribosyltransferase activity; orotidine-5'-phosphate decarboxylase activity

Biological Process: pyrimidine nucleoside biosynthetic process; UMP biosynthetic process

Disease: Orotic Aciduria
 UMPS ELISA Kit
 UMPS Recombinant
 UMPS Antibody
 OK/SW-cl.21 ELISA Kit
 OK/SW-cl.21 Recombinant
 OK/SW-cl.21 Antibody
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