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Vam6/Vps39-like protein

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May play a role in clustering and fusion of late endosomes and lysosomes (By similarity). Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription (By similarity).

Below are the list of possible Vam6/Vps39-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Vam6/Vps39-like protein

 Vam6/Vps39-like protein ELISA Kit
 Vam6/Vps39-like protein Recombinant
 Vam6/Vps39-like protein Antibody
VPS39: May play a role in clustering and fusion of late endosomes and lysosomes. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation. Belongs to the VAM6/VPS39 family. 2 isoforms of the human protein are produced by alterna
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tive splicing.

Protein type: G protein regulator, misc.; Membrane protein, peripheral

Cellular Component: late endosome membrane; lysosomal membrane

Molecular Function: protein binding

Biological Process: autophagy; endosomal vesicle fusion; endosome to lysosome transport; vesicle-mediated transport
 Vps39 ELISA Kit
 Vps39 Recombinant
 Vps39 Antibody
 Pldn ELISA Kit
 Pldn Recombinant
 Pldn Antibody
 Vam6 ELISA Kit
 Vam6 Recombinant
 Vam6 Antibody
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