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Vascular endothelial growth factor receptor

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Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the regulation of angiogenesis, cell survival, cell migration, macrophage function, and chemotaxis. Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates PLCG1. Promotes phosphorylation of AKT1 and CBL (By similarity).

Below are the list of possible Vascular endothelial growth factor receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Vascular endothelial growth factor receptor 1

 Vascular endothelial growth factor receptor 1 ELISA Kit
 Vascular endothelial growth factor receptor 1 Recombinant
 Vascular endothelial growth factor receptor 1 Antibody
Also known as Vascular endothelial growth factor receptor 1 (VEGFR-1).
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the regulation of angiogenesis, cell survival, cell migration, macrophage function, and chemotaxis. Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regu
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lator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates PLCG1. Promotes phosphorylation of AKT1 and CBL ().
 FLT1 ELISA Kit
 FLT1 Recombinant
 FLT1 Antibody
 VEGFR1 ELISA Kit
 VEGFR1 Recombinant
 VEGFR1 Antibody
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Vascular endothelial growth factor receptor 2

 Vascular endothelial growth factor receptor 2 ELISA Kit
 Vascular endothelial growth factor receptor 2 Recombinant
 Vascular endothelial growth factor receptor 2 Antibody
Also known as Vascular endothelial growth factor receptor 2 (VEGFR-2) (Endothelial kinase receptor EK1) (Quek 1) (Quek1).
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and/or VEGFD and plays an essential role in the regulation of angiogenesis and vascular development. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Binding of vascular growth factors leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling
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molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells ().
 KDR ELISA Kit
 KDR Recombinant
 KDR Antibody
 EK1 ELISA Kit
 EK1 Recombinant
 EK1 Antibody
 FLK-1 ELISA Kit
 FLK-1 Recombinant
 FLK-1 Antibody
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Vascular endothelial growth factor receptor 3

 Vascular endothelial growth factor receptor 3 ELISA Kit
 Vascular endothelial growth factor receptor 3 Recombinant
 Vascular endothelial growth factor receptor 3 Antibody
Also known as Vascular endothelial growth factor receptor 3 (VEGFR-3).
Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis.
 flt4 ELISA Kit
 flt4 Recombinant
 flt4 Antibody
 flt-4 ELISA Kit
 flt-4 Recombinant
 flt-4 Antibody
 vegfr3 ELISA Kit
 vegfr3 Recombinant
 vegfr3 Antibody
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Vascular endothelial growth factor receptor kdr-like

 Vascular endothelial growth factor receptor kdr-like ELISA Kit
 Vascular endothelial growth factor receptor kdr-like Recombinant
 Vascular endothelial growth factor receptor kdr-like Antibody
Also known as Vascular endothelial growth factor receptor kdr-like (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor-A) (Kinase insert domain receptor-like) (Protein-tyrosine kinase receptor flk-1) (Vascular endothelial growth factor receptor.
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be requi
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red for hematopoiesis.
 kdrl ELISA Kit
 kdrl Recombinant
 kdrl Antibody
 flk ELISA Kit
 flk Recombinant
 flk Antibody
 flk-1 ELISA Kit
 flk-1 Recombinant
 flk-1 Antibody
 flk1 ELISA Kit
 flk1 Recombinant
 flk1 Antibody
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