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Very long-chain acyl-CoA synthetase

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Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

Below are the list of possible Very long-chain acyl-CoA synthetase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Very long-chain acyl-CoA synthetase

 Very long-chain acyl-CoA synthetase ELISA Kit
 Very long-chain acyl-CoA synthetase Recombinant
 Very long-chain acyl-CoA synthetase Antibody
Also known as Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (Solute carrier family 27 member 2) (THCA-CoA liga.
SLC27A2: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving fr
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om the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.2.1.3; Ligase; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: endoplasmic reticulum lumen; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; integral to peroxisomal membrane; peroxisomal membrane

Molecular Function: enzyme binding; long-chain-fatty-acid-CoA ligase activity; phytanate-CoA ligase activity; receptor binding; very-long-chain-fatty-acid-CoA ligase activity

Biological Process: bile acid biosynthetic process; fatty acid alpha-oxidation; fatty acid beta-oxidation; long-chain fatty acid metabolic process
 SLC27A2 ELISA Kit
 SLC27A2 Recombinant
 SLC27A2 Antibody
 ACSVL1 ELISA Kit
 ACSVL1 Recombinant
 ACSVL1 Antibody
 FACVL1 ELISA Kit
 FACVL1 Recombinant
 FACVL1 Antibody
 FATP2 ELISA Kit
 FATP2 Recombinant
 FATP2 Antibody
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