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Very low-density lipoprotein receptor

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Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.

Below are the list of possible Very low-density lipoprotein receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Very low-density lipoprotein receptor

 Very low-density lipoprotein receptor ELISA Kit
 Very low-density lipoprotein receptor Recombinant
 Very low-density lipoprotein receptor Antibody
Also known as Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R).
VLDLR: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. Defects in VLDLR are the cause of cerebellar ataxia m
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ental retardation and dysequilibrium syndrome type 1 (CMARQ1); also known as dysequilibrium syndrome (DES) or non- progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: apical part of cell; cell surface; extracellular space; membrane; nucleus; perinuclear region of cytoplasm; receptor complex

Molecular Function: apolipoprotein binding; calcium-dependent protein binding; glycoprotein binding; protein binding; very-low-density lipoprotein binding; very-low-density lipoprotein receptor activity

Biological Process: dendrite morphogenesis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein kinase activity; receptor-mediated endocytosis; ventral spinal cord development
 Vldlr ELISA Kit
 Vldlr Recombinant
 Vldlr Antibody
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