| Very low-density lipoprotein receptor ELISA Kit|
Very low-density lipoprotein receptor Recombinant
Very low-density lipoprotein receptor Antibody
|Also known as Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R). |
VLDLR: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. Defects in VLDLR are the cause of cerebellar ataxia m
ental retardation and dysequilibrium syndrome type 1 (CMARQ1); also known as dysequilibrium syndrome (DES) or non- progressive cerebellar disorder with mental retardation. CMARQ1 is a congenital, non-progressive cerebellar ataxia associated with disturbed equilibrium, delayed ambulation, mental retardation and cerebellar hypoplasia. Additional features include short stature, strabismus, pes planus and, rarely, seizures. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: apical part of cell; cell surface; extracellular space; membrane; nucleus; perinuclear region of cytoplasm; receptor complex
Molecular Function: apolipoprotein binding; calcium-dependent protein binding; glycoprotein binding; protein binding; very-low-density lipoprotein binding; very-low-density lipoprotein receptor activity
Biological Process: dendrite morphogenesis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of protein kinase activity; receptor-mediated endocytosis; ventral spinal cord development
| Vldlr ELISA Kit|