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Vesicle-associated membrane protein-associated protein

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Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking.

Below are the list of possible Vesicle-associated membrane protein-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Vesicle-associated membrane protein-associated protein A

 Vesicle-associated membrane protein-associated protein A ELISA Kit
 Vesicle-associated membrane protein-associated protein A Recombinant
 Vesicle-associated membrane protein-associated protein A Antibody
Also known as Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A).
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle traff
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icking.
 VAPA ELISA Kit
 VAPA Recombinant
 VAPA Antibody
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Vesicle-associated membrane protein-associated protein B

 Vesicle-associated membrane protein-associated protein B ELISA Kit
 Vesicle-associated membrane protein-associated protein B Recombinant
 Vesicle-associated membrane protein-associated protein B Antibody
Also known as Vesicle-associated membrane protein-associated protein B (VAMP-B) (VAMP-associated protein B) (VAP-B).
Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
 VAPB ELISA Kit
 VAPB Recombinant
 VAPB Antibody
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Vesicle-associated membrane protein-associated protein B/C

 Vesicle-associated membrane protein-associated protein B/C ELISA Kit
 Vesicle-associated membrane protein-associated protein B/C Recombinant
 Vesicle-associated membrane protein-associated protein B/C Antibody
Also known as Vesicle-associated membrane protein-associated protein B/C (VAMP-B/VAMP-C) (VAMP-associated protein B/C) (VAP-B/VAP-C).
VAPB: Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 (ALS8). ALS8 is a familial f
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orm of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms. Defects in VAPB are a cause of spinal muscular atrophy proximal adult autosomal dominant (SMAPAD); also called late-onset spinal muscular atrophy Finkel type. A form of spinal muscular atrophy, a neuromuscular disorder characterized by degeneration of the anterior horn cells of the spinal cord, leading to symmetrical muscle weakness and atrophy. SMAPAD is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs, onset in late adulthood (after third decade) and a benign course. Most of the patients remain ambulatory 10 to 40 years after clinical onset. Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cell-cell adherens junction; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus

Molecular Function: beta-tubulin binding; enzyme binding; FFAT motif binding; microtubule binding; protein binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: cellular calcium ion homeostasis; endoplasmic reticulum organization and biogenesis; ER to Golgi vesicle-mediated transport; positive regulation of viral genome replication; sphingolipid biosynthetic process; unfolded protein response; unfolded protein response, activation of signaling protein activity; virus-host interaction

Disease: Amyotrophic Lateral Sclerosis 8; Spinal Muscular Atrophy, Late-onset, Finkel Type
 VAPB ELISA Kit
 VAPB Recombinant
 VAPB Antibody
 UNQ484/PRO983 ELISA Kit
 UNQ484/PRO983 Recombinant
 UNQ484/PRO983 Antibody
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Vesicle-associated membrane protein-associated protein C16G5.05c

 Vesicle-associated membrane protein-associated protein C16G5.05c ELISA Kit
 Vesicle-associated membrane protein-associated protein C16G5.05c Recombinant
 Vesicle-associated membrane protein-associated protein C16G5.05c Antibody
Also known as Vesicle-associated membrane protein-associated protein C16G5.05c (VAMP-associated protein C16G5.05c) (VAP homolog 1).
Targets proteins containing a FFAT motif to endoplasmic reticulum membranes.
 SPBC16G5.05c ELISA Kit
 SPBC16G5.05c Recombinant
 SPBC16G5.05c Antibody
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Vesicle-associated membrane protein-associated protein SCS2

 Vesicle-associated membrane protein-associated protein SCS2 ELISA Kit
 Vesicle-associated membrane protein-associated protein SCS2 Recombinant
 Vesicle-associated membrane protein-associated protein SCS2 Antibody
Also known as Vesicle-associated membrane protein-associated protein SCS2 (VAMP-associated protein SCS2) (Choline sensitivity suppressor protein 2) (VAP homolog 1).
Targets proteins containing a FFAT motif to endoplasmic reticulum membranes. Regulates phospholipid biosynthesis by modulating the subcellular localization of the transcriptional repressor OPI1.
 SCS2 ELISA Kit
 SCS2 Recombinant
 SCS2 Antibody
 YER120W ELISA Kit
 YER120W Recombinant
 YER120W Antibody
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Vesicle-associated membrane protein-associated protein SCS22

 Vesicle-associated membrane protein-associated protein SCS22 ELISA Kit
 Vesicle-associated membrane protein-associated protein SCS22 Recombinant
 Vesicle-associated membrane protein-associated protein SCS22 Antibody
Also known as Vesicle-associated membrane protein-associated protein SCS22 (VAMP-associated protein SCS22) (VAP homolog 2).
Targets proteins containing a FFAT motif to membranes (). Involved in regulation of phospholipid metabolism.
 SCS22 ELISA Kit
 SCS22 Recombinant
 SCS22 Antibody
 YBL091C-A ELISA Kit
 YBL091C-A Recombinant
 YBL091C-A Antibody
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