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Vitamin D 25-hydroxylase

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Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3).

Below are the list of possible Vitamin D 25-hydroxylase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Vitamin D 25-hydroxylase

 Vitamin D 25-hydroxylase ELISA Kit
 Vitamin D 25-hydroxylase Recombinant
 Vitamin D 25-hydroxylase Antibody
Also known as Vitamin D 25-hydroxylase (Cytochrome P450 2R1).
CYP2R1: Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). Defects in CYP2R1 are the cause of rickets vitamin D- dependent type 1B (VDDR1B); also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. A disorder caused by a selective deficiency of the active form of vitamin D
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(1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activityand low levels of 25-hydroxyvitamin D. Belongs to the cytochrome P450 family.

Protein type: EC 1.14.13.15; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p15.2

Cellular Component: endoplasmic reticulum membrane

Molecular Function: steroid hydroxylase activity; vitamin D3 25-hydroxylase activity

Biological Process: vitamin D metabolic process; vitamin metabolic process

Disease: Vitamin D Hydroxylation-deficient Rickets, Type 1b
 CYP2R1 ELISA Kit
 CYP2R1 Recombinant
 CYP2R1 Antibody
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