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WAS protein family

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Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and is required for its membrane targeting.

Below are the list of possible WAS protein family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

WAS protein family homolog 1

 WAS protein family homolog 1 ELISA Kit
 WAS protein family homolog 1 Recombinant
 WAS protein family homolog 1 Antibody
Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and is required for its membrane targeting.
 WASH1 ELISA Kit
 WASH1 Recombinant
 WASH1 Antibody
 RCJMB04_12b7 ELISA Kit
 RCJMB04_12b7 Recombinant
 RCJMB04_12b7 Antibody
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WAS protein family homolog 2

 WAS protein family homolog 2 ELISA Kit
 WAS protein family homolog 2 Recombinant
 WAS protein family homolog 2 Antibody
Also known as WAS protein family homolog 2 (CXYorf1-like protein on chromosome 2) (Protein FAM39B).
Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Involved in endocytic trafficking of EG
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F. Its assembly in the WASH core complex seems to inhibit its NPF activity and via FAM21 is required for its membrane targeting. Involved in transferrin receptor recycling. Regulates the trafficking of endosomal alpha5beta1 integrin to the plasma membrane and involved in invasive cell migration. In T-cells involved in endosome-to-membrane recycling of receptors including T-cell receptor (TCR), CD28 and ITGAL; proposed to be implicated in T-cell proliferation and effector function. In dendritic cells involved in endosome-to-membrane recycling of major histocompatibility complex (MHC) class II probably involving retromer and subsequently allowing antigen sampling, loading and presentation during T-cell activation. Involved in Arp2/3 complex-dependent actin assembly driving Salmonella typhimurium invasion independent of ruffling. Involved in the exocytosis of MMP14 leading to matrix remodeling during invasive migration and implicating late endosome-to-plasma membrane tubular connections and cooperation with the exocyst complex. Involved in negative regulation of autophagy independently from its role in endosomal sorting by inhibiting BECN1 ubiquitination to inactivate PIK3C3/Vps34 activity ().
 WASH2P ELISA Kit
 WASH2P Recombinant
 WASH2P Antibody
 FAM39B ELISA Kit
 FAM39B Recombinant
 FAM39B Antibody
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WAS protein family homolog 6

 WAS protein family homolog 6 ELISA Kit
 WAS protein family homolog 6 Recombinant
 WAS protein family homolog 6 Antibody
Also known as WAS protein family homolog 6 (Protein FAM39A).
May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
 WASH6P ELISA Kit
 WASH6P Recombinant
 WASH6P Antibody
 CXYorf1 ELISA Kit
 CXYorf1 Recombinant
 CXYorf1 Antibody
 FAM39A ELISA Kit
 FAM39A Recombinant
 FAM39A Antibody
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WAS protein family homolog DDB_G0292878

 WAS protein family homolog DDB_G0292878 ELISA Kit
 WAS protein family homolog DDB_G0292878 Recombinant
 WAS protein family homolog DDB_G0292878 Antibody
Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization.
 DDB_G0292878 ELISA Kit
 DDB_G0292878 Recombinant
 DDB_G0292878 Antibody
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