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WASH complex

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Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting .

Below are the list of possible WASH complex products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

WASH complex subunit CCDC53

 WASH complex subunit CCDC53 ELISA Kit
 WASH complex subunit CCDC53 Recombinant
 WASH complex subunit CCDC53 Antibody
Also known as WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53).
CCDC53: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Belongs to the CCDC53 family.

Chromosomal Location of Human Ortholog: 12q23.2

Cellular Component: actin cytoskeleton; intracellular membrane-bound organelle

Molecular Function: protein binding
 CCDC53 ELISA Kit
 CCDC53 Recombinant
 CCDC53 Antibody
 AD-016 ELISA Kit
 AD-016 Recombinant
 AD-016 Antibody
 CGI-116 ELISA Kit
 CGI-116 Recombinant
 CGI-116 Antibody
 x0009 ELISA Kit
 x0009 Recombinant
 x0009 Antibody
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WASH complex subunit CCDC53 homolog

 WASH complex subunit CCDC53 homolog ELISA Kit
 WASH complex subunit CCDC53 homolog Recombinant
 WASH complex subunit CCDC53 homolog Antibody
 DDB_G0267948 ELISA Kit
 DDB_G0267948 Recombinant
 DDB_G0267948 Antibody
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WASH complex subunit FAM21

 WASH complex subunit FAM21 ELISA Kit
 WASH complex subunit FAM21 Recombinant
 WASH complex subunit FAM21 Antibody
FAM21A: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Belongs to the FAM21 f
>>>
amily. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cytoplasm; early endosome; endosome; intracellular membrane-bound organelle; nucleolus; retromer complex

Molecular Function: phosphatidylinositol 3-phosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-5-phosphate binding

Biological Process: retrograde transport, endosome to Golgi
 Fam21 ELISA Kit
 Fam21 Recombinant
 Fam21 Antibody
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WASH complex subunit FAM21 homolog

 WASH complex subunit FAM21 homolog ELISA Kit
 WASH complex subunit FAM21 homolog Recombinant
 WASH complex subunit FAM21 homolog Antibody
Acts at least in part as component of the WASH complex which may regulate wash nucleation-promoting factor (NPF) activity and is required for its membrane targeting during endosomal sorting.
 CG16742 ELISA Kit
 CG16742 Recombinant
 CG16742 Antibody
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WASH complex subunit FAM21A

 WASH complex subunit FAM21A ELISA Kit
 WASH complex subunit FAM21A Recombinant
 WASH complex subunit FAM21A Antibody
FAM21A: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Belongs to the FAM21 f
>>>
amily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: cytoplasm; early endosome; intracellular membrane-bound organelle; nucleolus

Biological Process: retrograde transport, endosome to Golgi
 FAM21A ELISA Kit
 FAM21A Recombinant
 FAM21A Antibody
 FAM21B ELISA Kit
 FAM21B Recombinant
 FAM21B Antibody
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WASH complex subunit FAM21C

 WASH complex subunit FAM21C ELISA Kit
 WASH complex subunit FAM21C Recombinant
 WASH complex subunit FAM21C Antibody
Also known as WASH complex subunit FAM21C (Vaccinia virus penetration factor) (VPEF).
WASHC2C: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it prob
>>>
ably mediates the recruitment of the complex to endosome membranes. Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As a result, may facilitate the penetration of IMV into cells. Belongs to the FAM21 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 10q11.1

Cellular Component: cytoplasm; early endosome; endosome; intracellular membrane-bound organelle; nucleolus; retromer complex

Molecular Function: phosphatidylinositol 3-phosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-5-phosphate binding; protein binding

Biological Process: retrograde transport, endosome to Golgi
 FAM21C ELISA Kit
 FAM21C Recombinant
 FAM21C Antibody
 KIAA0592 ELISA Kit
 KIAA0592 Recombinant
 KIAA0592 Antibody
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WASH complex subunit strumpellin

 WASH complex subunit strumpellin ELISA Kit
 WASH complex subunit strumpellin Recombinant
 WASH complex subunit strumpellin Antibody
KIAA0196: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Defects in KIAA0196 are the cause of spastic paraplegia autosomal dominant type 8 (SPG8). Spastic paraplegia is
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a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Belongs to the strumpellin family.

Cellular Component: early endosome; endosome

Biological Process: endosome transport; oocyte maturation; polar body extrusion after meiotic divisions
 Kiaa0196 ELISA Kit
 Kiaa0196 Recombinant
 Kiaa0196 Antibody
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WASH complex subunit strumpellin homolog

 WASH complex subunit strumpellin homolog ELISA Kit
 WASH complex subunit strumpellin homolog Recombinant
 WASH complex subunit strumpellin homolog Antibody
 DDB_G0288569 ELISA Kit
 DDB_G0288569 Recombinant
 DDB_G0288569 Antibody
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WASH complex subunit SWIP

 WASH complex subunit SWIP ELISA Kit
 WASH complex subunit SWIP Recombinant
 WASH complex subunit SWIP Antibody
KIAA1033: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Belongs to the WASHS7 family. 2 isoforms of the human protein are produced by alternative splicing.

Prot
>>>
ein type: Unknown function

Cellular Component: endosome; nucleoplasm

Biological Process: endosome organization and biogenesis; endosome transport
 Kiaa1033 ELISA Kit
 Kiaa1033 Recombinant
 Kiaa1033 Antibody
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WASH complex subunit SWIP homolog

 WASH complex subunit SWIP homolog ELISA Kit
 WASH complex subunit SWIP homolog Recombinant
 WASH complex subunit SWIP homolog Antibody
 DDB_G0283355 ELISA Kit
 DDB_G0283355 Recombinant
 DDB_G0283355 Antibody
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