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WD repeat-containing and planar cell polarity effector protein

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Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Functions cell autonomously to regulate wing cell hair polarity and number.

Below are the list of possible WD repeat-containing and planar cell polarity effector protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

WD repeat-containing and planar cell polarity effector protein fritz

 WD repeat-containing and planar cell polarity effector protein fritz ELISA Kit
 WD repeat-containing and planar cell polarity effector protein fritz Recombinant
 WD repeat-containing and planar cell polarity effector protein fritz Antibody
Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Functions cell autonomously to regulate wing cell hair polarity and number.
 frtz ELISA Kit
 frtz Recombinant
 frtz Antibody
 CG17657 ELISA Kit
 CG17657 Recombinant
 CG17657 Antibody
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WD repeat-containing and planar cell polarity effector protein fritz homolog

 WD repeat-containing and planar cell polarity effector protein fritz homolog ELISA Kit
 WD repeat-containing and planar cell polarity effector protein fritz homolog Recombinant
 WD repeat-containing and planar cell polarity effector protein fritz homolog Antibody
Also known as WD repeat-containing and planar cell polarity effector protein fritz homolog (hFRTZ) (Bardet-Biedl syndrome 15 protein) (WD repeat-containing and planar cell polarity effector protein).
LOC51057: Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Defects in WDPCP are the cause of Bardet-Biedl syndrome type 15 (BBS15). Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset o
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besity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease. Mutations in WDPCP may act as modifiers of the phenotypic expression of Bardet-Biedl syndrome and Meckel syndrome by interacting in trans with primary BBS and MKS loci. Belongs to the WD repeat fritz family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: apical plasma membrane; axoneme; cell cortex; plasma membrane

Biological Process: establishment of planar polarity; establishment of protein localization; regulation of protein localization; septin cytoskeleton organization and biogenesis; shape changes of embryonic cells

Disease: Bardet-biedl Syndrome 15; Congenital Heart Defects, Hamartomas Of Tongue, And Polysyndactyly
 WDPCP ELISA Kit
 WDPCP Recombinant
 WDPCP Antibody
 BBS15 ELISA Kit
 BBS15 Recombinant
 BBS15 Antibody
 C2orf86 ELISA Kit
 C2orf86 Recombinant
 C2orf86 Antibody
 FRITZ ELISA Kit
 FRITZ Recombinant
 FRITZ Antibody
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