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Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear.

Below are the list of possible Whirlin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.


 Whirlin ELISA Kit
 Whirlin Recombinant
 Whirlin Antibody
WHRN: Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Defects in WHRN are the cause of deafness autosomal recessive type 31 (DFNB31). DFNB31 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Defects in WHRN are the cause of Usher syndrome type 2D (USH2D). USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa a
nd sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH2 is characterized by congenital mild hearing impairment with normal vestibular responses. 4 isoforms of the human protein are produced by alternative splicing.

Cellular Component: actin filament; axon; cell soma; cilium; cytoplasm; dendrite; dendritic shaft; membrane; photoreceptor connecting cilium; photoreceptor inner segment; stereocilium; stereocilium bundle; stereocilium bundle tip; synapse

Molecular Function: protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: auditory receptor cell stereocilium organization and biogenesis; cerebellar Purkinje cell layer formation; establishment of protein localization; inner ear receptor stereocilium organization and biogenesis; retinal homeostasis; sensory perception of light stimulus; sensory perception of sound
 Whrn ELISA Kit
 Whrn Recombinant
 Whrn Antibody
 Dfnb31 ELISA Kit
 Dfnb31 Recombinant
 Dfnb31 Antibody
 Kiaa1526 ELISA Kit
 Kiaa1526 Recombinant
 Kiaa1526 Antibody
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