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Wings apart-like protein

Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair (By similarity).

Below are the list of possible Wings apart-like protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Wings apart-like protein homolog

 Wings apart-like protein homolog ELISA Kit
 Wings apart-like protein homolog Recombinant
 Wings apart-like protein homolog Antibody
Also known as Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2) (WAPL cohesin release factor).
WAPL: a chromatin-associated protein partner of Epstein-Barr nuclear protein 2. Associated with cervical carcinogenesis and tumor progression.

Protein type: DNA-binding

Cellular Component: chromatin; cohesin complex; cytoplasm; intracellular membrane-bound organelle; microtubule cytoskeleton; nucleoplasm; nucleus; synaptonemal complex

Biological Process: meiotic chromosome segregation; mitosis; mitotic sister chromatid cohesion; negative regulation of DNA re
plication; negative regulation of sister chromatid cohesion; positive regulation of fibroblast proliferation; regulation of chromosome segregation; response to toxin
 Wapl ELISA Kit
 Wapl Recombinant
 Wapl Antibody
 Kiaa0261 ELISA Kit
 Kiaa0261 Recombinant
 Kiaa0261 Antibody
 Wapal ELISA Kit
 Wapal Recombinant
 Wapal Antibody
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Wings apart-like protein homolog 1

 Wings apart-like protein homolog 1 ELISA Kit
 Wings apart-like protein homolog 1 Recombinant
 Wings apart-like protein homolog 1 Antibody
Regulator of meiotic chromosome structure and function, playing a role in sister chromatid cohesion, possibly via antagonizing the coh-3/-4 association with axial elements in nuclei during late prophase, cohesin association with chromatin, DNA double strand break repair and polar body positioning following meiotic divisions during oogenesis. Regulates the morphogenesis and temporal assembly of axi
al elements to control the organization of meiotic chromosomes in pachytene nuclei and is also involved in meiotic chromosomal remodeling in late pachytene nuclei.
 wapl-1 ELISA Kit
 wapl-1 Recombinant
 wapl-1 Antibody
 R08C7.10 ELISA Kit
 R08C7.10 Recombinant
 R08C7.10 Antibody
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