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Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store.

Below are the list of possible Wolframin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.


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WFS1: Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store. Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.

Protein type: Endoplasmic reticulum; Membra
ne protein, integral; Membrane protein, multi-pass

Cellular Component: endoplasmic reticulum; integral to endoplasmic reticulum membrane; proteasome complex

Molecular Function: ATPase binding; calcium-dependent protein binding; calmodulin binding; transcription activator binding; ubiquitin protein ligase binding

Biological Process: calcium ion homeostasis; endoplasmic reticulum calcium ion homeostasis; ER-associated protein catabolic process; glucose homeostasis; kidney development; negative regulation of neuron apoptosis; negative regulation of programmed cell death; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; neurological system process; positive regulation of adenylate cyclase activity; positive regulation of calcium ion transport; positive regulation of growth; positive regulation of protein metabolic process; positive regulation of protein ubiquitination; protein stabilization; renal water homeostasis; sensory perception of sound; unfolded protein response; visual perception
 Wfs1 ELISA Kit
 Wfs1 Recombinant
 Wfs1 Antibody
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