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Zinc metalloproteinase-disintegrin-like acurhagin

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Snake venom zinc metalloprotease that causes hemorrhage and dose-dependently inhibits platelet aggregation triggered by collagen. This inhibition is due to its binding to glycoprotein VI (GP6) and collagen. The binding to GP6 results in inhibition of the signaling pathway (decrease of tyrosine phosphorylation of signaling proteins such as Syk, LAT, PI3-K and PLCgamma2). Preferentially cleaves alpha chain (FGA) of fibrinogen, followed by beta chain (FGB). Also degrades the extracellular matrix protein fibronectin (FN1), and cleaves collagen and von Willebrand factor (VWF).

Below are the list of possible Zinc metalloproteinase-disintegrin-like acurhagin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Zinc metalloproteinase-disintegrin-like acurhagin

 Zinc metalloproteinase-disintegrin-like acurhagin ELISA Kit
 Zinc metalloproteinase-disintegrin-like acurhagin Recombinant
 Zinc metalloproteinase-disintegrin-like acurhagin Antibody
Also known as Zinc metalloproteinase-disintegrin-like acurhagin (Acur) (Acutolysin e2) (Snake venom metalloproteinase) (SVMP) (Zinc metalloproteinase-disintegrin-like acutolysin-E).
Snake venom zin
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c metalloprotease that causes hemorrhage and dose-dependently inhibits platelet aggregation triggered by collagen. This inhibition is due to its binding to glycoprotein VI (GP6) and collagen. The binding to GP6 results in inhibition of the signaling pathway (decrease of tyrosine phosphorylation of signaling proteins such as Syk, LAT, PI3-K and PLCgamma2). Preferentially cleaves alpha chain (FGA) of fibrinogen, followed by beta chain (FGB). Also degrades the extracellular matrix protein fibronectin (FN1), and cleaves collagen and von Willebrand factor (VWF).
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