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Zinc metalloproteinase-disintegrin-like alternagin

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Zinc metalloproteinase-disintegrin-like alternagin: hemorrhagic protease that acts as a potent inhibitor of collagen-induced adhesion by blockage of alpha-2/beta-1 (ITGA2/ITGB1) integrin.; Disintegrin alternagin-C: potent inhibitor of the collagen binding to alpha-2/beta-1 (ITGA2/ITGB1) integrin. Has a chemotactic activity on neutrophils and this effect involves actin cytoskeleton rearrangement, FAK, PI3-kinase and Erk-2 activities. Induces endothelial cell proliferation, and these effects are mediated at least in part by an increased expression of vascular endothelial growth factor (VEGF). In injured muscles, reduces both MMP-2 mRNA and gelatinolytic activity, suggesting that it changes the overall balance of extracellular matrix protein turnover during muscle regeneration. In low concentrations, induces formation of new vessels and up-regulates the expression of VEGF receptor 2 (KDR) without affecting VEGF receptor 1 (FLT1) expression. In high concentrations, strongly inhibits angiogenesis, and the expression of both receptors is down-regulated. Has very low plasma clotting activity.

Below are the list of possible Zinc metalloproteinase-disintegrin-like alternagin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Zinc metalloproteinase-disintegrin-like alternagin

 Zinc metalloproteinase-disintegrin-like alternagin ELISA Kit
 Zinc metalloproteinase-disintegrin-like alternagin Recombinant
 Zinc metalloproteinase-disintegrin-like alternagin Antibody
Also known as Zinc metalloproteinase-disintegrin-like alternagin (Snake venom metalloproteinase) (SVMP).
Zinc metalloproteinase-disintegrin-like alternagin: hemorrhagic protease that acts as a pote
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nt inhibitor of collagen-induced adhesion by blockage of alpha-2/beta-1 (ITGA2/ITGB1) integrin.
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