• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Achaete-scute

Transcriptional regulator (By similarity). AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Activates transcription by binding to the E box (5'-CANNTG-3').

Below are the list of possible Achaete-scute products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Achaete-scute homolog 1

Transcriptional regulator (). AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Activates transcription by binding to the E box (5'-CANNTG-3').

Achaete-scute homolog 1a

Also known as Achaete-scute homolog 1a (Zash-1a) (Pituitary-absent protein).
Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (). Involved in neurogenesis. Required for the development of neurons in the epiphysis, acting partially redundantly with neurog1 and downstream of flh. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. Also involved in pituitary development; required cell-autonomously in adenohypophyseal cells for endocrine differentiation and for survival of a subset of cells.

Achaete-scute homolog 1b

Also known as Achaete-scute homolog 1b (Zash-1b).
Transcriptional regulator. May mediate transcription activation by binding to the E box-containing promoter (). Involved in neurogenesis. Involved in maintaining rhombomere boundaries in the hindbrain, probably via up-regulation of delta expression. May mediate transcription activation by binding to the E box-containing promoter.

Achaete-scute homolog 2

Also known as Achaete-scute homolog 2 (ASH-2) (hASH2) (Class A basic helix-loop-helix protein 45) (bHLHa45) (Mash2).
ASCL2: a basic helix-loop-helix transcription factor, plays an essential role in the maintenance of adult intestinal stem cells

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; nucleus

Biological Process: negative regulation of transcription from RNA polymerase II promoter; regulation of neurogenesis; response to hypoxia; transcription, DNA-dependent

Achaete-scute homolog 3

Also known as Achaete-scute homolog 3 (ASH-3) (hASH3) (Class A basic helix-loop-helix protein 42) (bHLHa42) (bHLH transcriptional regulator Sgn-1).
ASCL3: Transcriptional repressor. Inhibits myogenesis.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 11p15.3

Molecular Function: DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent

Achaete-scute homolog 4

Also known as Achaete-scute homolog 4 (ASH-4) (hASH4) (Achaete-scute-like protein 4) (Class A basic helix-loop-helix protein 44) (bHLHa44).
ASCL4: Could be a transcriptional regulator involved in skin development.

Chromosomal Location of Human Ortholog: 12q23.3

Molecular Function: protein binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter

Achaete-scute homolog 5

Also known as Achaete-scute homolog 5 (ASH-5) (hASH5) (Class A basic helix-loop-helix protein 47) (bHLHa47).
ASCL5:

Protein type: DNA-binding; Transcription regulation

Chromosomal Location of Human Ortholog: 1q32.1

Molecular Function: transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter
Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000