• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Actin filament-associated protein

Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Below are the list of possible Actin filament-associated protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Actin filament-associated protein 1

Also known as Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110).
AFAP: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: focal adhesion

Actin filament-associated protein 1-like 2

Also known as Actin filament-associated protein 1-like 2 (AFAP1-like protein 2).
AFAP1L2: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Activator; Cell cycle regulation

Cellular Component: cytoplasm; plasma membrane

Molecular Function: protein tyrosine kinase activator activity; SH2 domain binding; SH3 domain binding

Biological Process: inflammatory response; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of interleukin-8 production; positive regulation of transcription, DNA-dependent; regulation of interleukin-6 production; regulation of mitotic cell cycle

Go back to Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000