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Actin-regulating kinase

Involved in regulation of actin cytoskeleton organization and endocytosis.

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Actin-regulating kinase PRK1

Protein kinase involved in regulation of actin cytoskeleton organization and endocytosis. Phosphorylates the endocytic protein SLA1. The CDC28-CLN3 complex phosphorylation of SLA1 enhances its further phosphorylation by PRK1, weakening SLA1 association with PAN1, an activator of the actin-nucleating ARP2/3 complex. Plays a role in cell wall regulation and required for oxidative stress survival.

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