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Acyl-CoA:lysophosphatidylglycerol acyltransferase

Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor.

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Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

LPGAT1: Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: EC 2.3.1.-; Membrane protein, integral; Membrane protein, multi-pass; Transferase

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: cytoplasm; endoplasmic reticulum membrane; membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity
Proteins Root Name Listing
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