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Acyl-CoA dehydrogenase family

Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA.

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Acyl-CoA dehydrogenase family member 10

Also known as Acyl-CoA dehydrogenase family member 10 (ACAD-10).
ACAD10: Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA. Belongs to the acyl-CoA dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.3.99.-; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 12q24.12

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding

Biological Process: fatty acid beta-oxidation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; lipid homeostasis

Acyl-CoA dehydrogenase family member 11

Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat.

Acyl-CoA dehydrogenase family member 9

Also known as Acyl-CoA dehydrogenase family member 9, mitochondrial (ACAD-9).
ACAD9: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0). Belongs to the acyl-CoA dehydrogenase family.

Protein type: EC 1.3.99.-; Mitochondrial; Oxidoreductase

Cellular Component: dendrite; mitochondrion; nucleus

Molecular Function: acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding

Biological Process: fatty acid beta-oxidation using acyl-CoA dehydrogenase; lipid homeostasis; mitochondrial respiratory chain complex I assembly
Proteins Root Name Listing
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