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Acyl-CoA wax alcohol acyltransferase

Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).

Below are the list of possible Acyl-CoA wax alcohol acyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Acyl-CoA wax alcohol acyltransferase 1

Also known as Acyl-CoA wax alcohol acyltransferase 1 (Diacylglycerol O-acyltransferase 2-like protein 3) (Diacylglycerol acyltransferase 2) (Long-chain-alcohol O-fatty-acyltransferase 1).
DGAT2L3: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20). Belongs to the diacylglycerol acyltransferase family.

Protein type: EC 2.3.1.75; Membrane protein, integral; Membrane protein, multi-pass; Transferase

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: long-chain-alcohol O-fatty-acyltransferase activity

Biological Process: arachidonic acid metabolic process; wax biosynthetic process

Acyl-CoA wax alcohol acyltransferase 2

Also known as Acyl-CoA wax alcohol acyltransferase 2 (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (Diacylglycerol O-acyltransferase 2-like protein 4) (Diacylglycerol O-acyltransferase candidate 4) (hDC4.
DGAT2L4: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl- CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo. Belongs to the diacylglycerol acyltransferase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; EC 2.3.1.75; EC 2.3.1.76; Lipid Metabolism - glycerolipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: endoplasmic reticulum membrane

Molecular Function: 2-acylglycerol O-acyltransferase activity; long-chain-alcohol O-fatty-acyltransferase activity; retinol O-fatty-acyltransferase activity

Biological Process: cellular lipid metabolic process; wax biosynthetic process
Proteins Root Name Listing
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