• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Adenosylhomocysteinase

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Below are the list of possible Adenosylhomocysteinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Adenosylhomocysteinase

Also known as Adenosylhomocysteinase (AdoHcyase) (CUBP) (Liver copper-binding protein) (S-adenosyl-L-homocysteine hydrolase).
SAHH: Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD). A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy. Belongs to the adenosylhomocysteinase family.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 3.3.1.1; Hydrolase; Other Amino Acids Metabolism - selenoamino acid

Cellular Component: cytoplasm; cytosol; neuron projection; nucleus

Molecular Function: adenosylhomocysteinase activity; adenyl nucleotide binding; copper ion binding; identical protein binding; NAD binding; protein self-association

Biological Process: chronic inflammatory response to antigenic stimulus; circadian sleep/wake cycle; response to nutrient; S-adenosylhomocysteine catabolic process; S-adenosylmethionine cycle

Adenosylhomocysteinase 1

Also known as Adenosylhomocysteinase 1 (AdoHcyase 1) (Protein EMBRYO DEFECTIVE 1395) (Protein HOMOLOGY-DEPENDENT GENE SILENCING 1) (S-adenosyl-L-homocysteine hydrolase 1) (SAH hydrolase 1).
Encodes a S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing.

Adenosylhomocysteinase 2

Also known as Adenosylhomocysteinase 2 (AdoHcyase 2) (DC-expressed AHCY-like molecule) (IP(3)Rs binding protein released with IP(3)) (IRBIT) (S-adenosyl-L-homocysteine hydrolase 2) (S-adenosylhomocysteine hydrolase-like protein 1).
AHCYL1: an inositol 1,4,5-trisphosphate receptor 1 (IP3R1)-binding protein that inhibits IP3 binding to IP3R1 and IP3-induced intracellular Ca2 release. Suppresses the activation of IP3R1 via a phosphorylation-dependent mechanism. Also binds the Na/HCO3 cotransporter 1 (SLC4A4) and may play an important role in pH regulation. Contains a domain homologous to S-adenosylhomocysteine hydrolase (SAHH), although it is reported to possess no hydrolase activity. Its expression is induced in cultured monocytes when they are differentiated into dendritic cells (DC) by exposure to GM-CSF and IL-4.

Protein type: Amino Acid Metabolism - cysteine and methionine; EC 3.3.1.1; Hydrolase; Other Amino Acids Metabolism - selenoamino acid

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: apical plasma membrane; cytoplasm; cytosol; endoplasmic reticulum membrane

Molecular Function: adenosylhomocysteinase activity; identical protein binding; protein binding

Biological Process: mRNA polyadenylation; regulation of ion transmembrane transporter activity; regulation of mRNA 3'-end processing; response to calcium ion; S-adenosylmethionine cycle

Adenosylhomocysteinase 3

Also known as Adenosylhomocysteinase 3 (AdoHcyase 3) (IP(3)Rs binding protein released with IP(3) 2) (IRBIT2) (Long-IRBIT).
May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg2+-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate ().

Adenosylhomocysteinase A

Also known as Adenosylhomocysteinase A (AdoHcyase A) (S-adenosyl-L-homocysteine hydrolase A).
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Adenosylhomocysteinase B

Also known as Adenosylhomocysteinase B (AdoHcyase B) (S-adenosyl-L-homocysteine hydrolase B).
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000