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Adiponectin receptor protein

Adiponectin receptor. In insulin-producing cells, regulates insulin secretion and controls glucose and lipid metabolism.

Below are the list of possible Adiponectin receptor protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Adiponectin receptor protein 1

ADIPOR1: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. Belongs to the ADIPOR family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: intrinsic to plasma membrane; membrane; plasma membrane

Molecular Function: adiponectin binding; identical protein binding; protein heterodimerization activity; protein kinase binding; receptor activity

Biological Process: adiponectin-mediated signaling pathway; fatty acid oxidation; glucose homeostasis; hormone-mediated signaling; leptin-mediated signaling pathway; negative regulation of cell growth; negative regulation of JAK-STAT cascade; positive regulation of insulin receptor signaling pathway; positive regulation of JAK-STAT cascade; regulation of lipid metabolic process

Adiponectin receptor protein 2

ADIPOR2: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. Belongs to the ADIPOR family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Cellular Component: intrinsic to plasma membrane; plasma membrane

Molecular Function: adiponectin binding; identical protein binding; protein heterodimerization activity; receptor activity

Biological Process: adiponectin-mediated signaling pathway; fatty acid oxidation; G-protein coupled receptor protein signaling pathway; glucose homeostasis; hormone-mediated signaling; negative regulation of cell growth; positive regulation of glucose import

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