Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a redox sensor to monitor oxygen levels.
Energy taxis includes aerotaxis, redox taxis and glycerol taxis. aer is up-regulated by FlhCD and CRP. aer mutants are down for genes involved in anaerobic respiration and the Entner-Doudoroff pathway. [More information is available at EcoGene: EG12955]. The flavoprotein Aer is one of two sensory proteins which mediate the aerotactic response in Escherichia coli. [More information is available at EcoCyc: G7595].