• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Alcohol dehydrogenase

CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone + NADH. .

Below are the list of possible Alcohol dehydrogenase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Alcohol dehydrogenase [NADP

Also known as Alcohol dehydrogenase [NADP(+)] (3-DG-reducing enzyme) (Aldehyde reductase) (Aldo-keto reductase family 1 member A1).
AKR1A1: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Belongs to the aldo/keto reductase family.

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.1.1.2; Lipid Metabolism - glycerolipid; Oxidoreductase

Cellular Component: apical plasma membrane; cytosol; extracellular space

Molecular Function: aldehyde reductase activity; L-glucuronate reductase activity

Biological Process: aldehyde catabolic process; D-glucuronate catabolic process; L-ascorbic acid biosynthetic process

Alcohol dehydrogenase 4

Also known as Alcohol dehydrogenase 4 (ADH2) (Alcohol dehydrogenase class II) (Alcohol dehydrogenase II).
ADH4: class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; aldehyde reductase activity; all-trans retinal binding; benzaldehyde dehydrogenase activity; ethanol binding; NAD binding; NADPH:quinone reductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; retinol binding; retinol dehydrogenase activity; zinc ion binding

Biological Process: alcohol catabolic process; alcohol metabolic process; aldehyde metabolic process; ethanol metabolic process; ethanol oxidation; retinoid metabolic process; retinol metabolic process

Alcohol dehydrogenase 6

ADH6: class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Alcohol dehydrogenase class 4 mu/sigma chain

Also known as Alcohol dehydrogenase class 4 mu/sigma chain (ADH-C2) (Alcohol dehydrogenase 7) (Alcohol dehydrogenase class IV mu/sigma chain) (Gastric alcohol dehydrogenase) (Retinol dehydrogenase).
ADH7: Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism. Belongs to the zinc-containing alcohol dehydrogenase family. Class-IV subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Cellular Component: intracellular

Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; aldehyde oxidase activity; ethanol binding; NAD binding; oxidoreductase activity; protein homodimerization activity; receptor antagonist activity; retinol binding; retinol dehydrogenase activity; zinc ion binding

Biological Process: ethanol catabolic process; ethanol metabolic process; ethanol oxidation; fatty acid omega-oxidation; response to bacterium; response to ethanol; retinoic acid metabolic process; retinoid metabolic process; retinol metabolic process

Alcohol dehydrogenase class-3

Also known as Alcohol dehydrogenase class-3 (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase B2) (ADH-B2) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (S.
ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; EC 1.1.1.284; Energy Metabolism - methane; Lipid Metabolism - fatty acid; Mitochondrial; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450

Cellular Component: cytoplasm; mitochondrion; nucleus

Molecular Function: alcohol dehydrogenase activity; fatty acid binding; formaldehyde dehydrogenase activity; protein homodimerization activity; S-(hydroxymethyl)glutathione dehydrogenase activity; zinc ion binding

Biological Process: aging; ethanol catabolic process; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; positive regulation of blood pressure; respiratory system process; response to lipopolysaccharide; response to nitrosative stress; response to redox state; retinoid metabolic process

Alcohol dehydrogenase class-P

Also known as Alcohol dehydrogenase class-P (AtADH).
Catalyzes the reduction of acetaldehyde using NADH as reductant. Requires zinc for activity. Dimer. Anaerobic response polypeptide (ANP). Fermentation. The protein undergoes thiolation following treatment with the oxidant tert-butylhydroperoxide.

Alcohol dehydrogenase patD

Also known as Alcohol dehydrogenase patD (Patulin synthesis protein D).
Alcohol dehydrogenase; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (PubMed:19383676, PubMed:24334092). The pathway begins with the synthesis of 6-methylsalicylic acid by the polyketide synthase (PKS) patK via condensation of acetate and malonate units (PubMed:19383676). PatG then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol (PubMed:24334092). The cytochrome P450 monooxygenase patH then converts m-cresol to m-hydroxybenzyl alcohol, which is further converted to gentisyl alcohol by the cytochrome P450 monooxygenase patI (PubMed:19383676). The conversion of gentisyl alcohol to two-ring compound neopatulin remains a matter of speculation, but it involves at least two intermediates, isoepoxydon and phyllostin (PubMed:19383676). PatN catalyzes the transformation of isoepoxydon into phyllostin (PubMed:19383676). The last part of the biosynthetic pathway involves the conversion of neopatulin to ascladiol followed by the transformation of the latter into patulin (PubMed:19383676).

Alcohol dehydrogenase YqhD

AFMB Structural Genomics target Number 57 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13014]. YqhD is an NADP-dependent aldehyde dehydrogenase which may be part of a glutathione-independent response to lipid peroxidation . report that various alcohols, aldehydes, amino acids, sugars and -hydroxy acids were tested as substrates for YqhD. [More information is available at EcoCyc: G7564].

Alcohol dehydrogenase, propanol-preferring

Medium chain dehydrogenase/reductase (MDR) activity reported by Shafqat (1999). [More information is available at EcoGene: EG12622]. AdhP is an ethanol-active medium-chain alcohol dehydrogenase/reductase. [More information is available at EcoCyc: G6775].
Proteins Root Name Listing
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000