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Alpha-1,3-galactosyltransferase

Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Synthesis of iGb3 is the initial step in the formation of the isoglobo-series glycolipid pathway and is the precursor to isogloboside 4 (iGb4) and isoForssman glycolipids. Can glycosylate only lipids and not proteins and is solely responsible for initiating the synthesis of isoglobo-series glycosphingolipids.

Below are the list of possible Alpha-1,3-galactosyltransferase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the reer's specifications.

Alpha-1,3-galactosyltransferase 2

Also known as Alpha-1,3-galactosyltransferase 2 (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S).
A3GALT2: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures. Belongs to the glycosyltransferase 6 family.

Protein type: EC 2.4.1.87; Transferase

Cellular Component: Golgi apparatus; vesicle

Molecular Function: alpha-1,3-galactosyltransferase activity; transferase activity, transferring glycosyl groups

Biological Process: glycosphingolipid biosynthetic process; lipid glycosylation

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